Treponema ruminis: DYE50_03370
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Entry
DYE50_03370 CDS
T07166
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tri
Treponema ruminis
Pathway
tri00300
Lysine biosynthesis
tri00550
Peptidoglycan biosynthesis
tri01100
Metabolic pathways
tri01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tri00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DYE50_03370 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DYE50_03370 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DYE50_03370 (murF)
Enzymes [BR:
tri01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DYE50_03370 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QSI01618
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Position
761170..762657
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AA seq
495 aa
AA seq
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MTDALCVENIESLLKLSETLEAVGGVLLNGNFPEQNFCFTSVQTDSRLIAEKSLFVPLIG
EFQDGHSYIPQALEKGASAVFISKKTSKNLLEALKKEAADNKNVAFILVENTMQALQKAA
AAYVRKFPRLIRCAVTGSSGKTTTKEITASILRQKFSVIATKGNFNSETGLPLSVFNIRS
EHELGLFEMGMNRVNEIGEIAEVFKPNYAIITNIGTAHIGILGSRQNIANEKKKIFTYID
SFGAAFIPEKDDFASFLEKGVKGKVVKYGVDCDESVKLIADEGLSGTVFSVDGLEMRLSL
PGKYNFLNALGAIALAKTLGCTAEQIKTGIESLKPLGGRSTIKKGKFTVLEDCYNANPDS
MEKALDLCADTKIQGKKIYVLGDMLELGEESEKEHARIGEKALFSDADMIVFFGFEMNFA
FEKAIEIAERKSSLADEKISSVRLVYIGNKDEAAVNDAAKEISEFAESGDLIMLKGSRGM
GLERILPLIGMGGES
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
atgacagacgctctttgtgtcgaaaatatagaaagtctcttgaaattgtcagaaaccctt
gaagcagtgggaggagttcttcttaacgggaatttcccggagcagaacttttgcttcacg
agcgtgcagactgacagccgtttgatcgcggaaaaatctctctttgttcccctcatcggt
gaatttcaggacgggcattcctatattcctcaggcacttgaaaaaggcgcgtctgccgtt
tttatttctaaaaaaacatctaaaaatctccttgaggccttgaaaaaagaggccgctgat
aacaaaaatgtagcctttattctggtggagaacacaatgcaggccctgcagaaagcggcg
gctgcctatgtccgtaagtttccccgtcttattcgctgtgctgtgactggttcaagcggc
aaaacaacgactaaggaaattacggcatcaatcctccgccagaaattttctgtcattgcc
acaaaaggcaacttcaattcagagactggtcttcctctttccgtcttcaatatccgcagc
gagcatgagctgggactttttgagatgggaatgaaccgcgtaaacgaaatcggtgagatt
gcagaagtcttcaagcctaattacgcaatcataaccaacatcggtacagcccacatcgga
attttgggaagccgacagaacattgcaaacgaaaagaaaaagattttcacttatatagat
tcattcggggctgcctttatccctgaaaaagacgattttgcatctttccttgaaaaagga
gttaagggcaaggtcgtaaaatacggcgtcgactgcgatgaaagcgtaaagcttattgct
gatgaaggactttccggtactgtctttagcgttgacggtcttgaaatgcgcctttccctt
cctggaaaatataatttcctcaatgccctcggagcaatcgccctggcaaagactctgggc
tgcactgcagagcagattaagactggaattgaaagcctcaagcctctcggtggccgctct
acaatcaaaaagggcaaatttactgtccttgaggactgctacaacgcaaatcctgactca
atggaaaaagccctcgacctctgcgctgacacaaaaatccagggcaaaaaaatctatgtt
ctgggcgatatgctggagcttggcgaggaatcagaaaaagagcacgctagaatcggcgaa
aaagccctcttttctgatgctgacatgattgtcttcttcggttttgagatgaattttgct
tttgaaaaggcaattgaaatcgccgagagaaaatcttcccttgcagacgagaaaatttct
tccgtccgcctggtttatatcggaaacaaagacgaagcggctgtaaatgatgccgcaaaa
gaaatatctgaatttgccgaaagcggtgacctgattatgctcaagggctctcgtggaatg
ggccttgagcggattctgcctctgatcggaatggggggcgagtcgtga
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