Trichomycterus rosablanca: 134310092
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Entry
134310092 CDS
T09921
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
trn
Trichomycterus rosablanca
Brite
KEGG Orthology (KO) [BR:
trn00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
trn01001
]
134310092 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
trn04131
]
134310092 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
trn04147
]
134310092 (lrrk2)
Enzymes [BR:
trn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
134310092 (lrrk2)
Protein kinases [BR:
trn01001
]
Serine/threonine kinases: TKL group
LRRK family
134310092 (lrrk2)
Membrane trafficking [BR:
trn04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
134310092 (lrrk2)
Exosome [BR:
trn04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
134310092 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
COR
Roc
Ras
LRR_14
WD40_CDC20-Fz
WDR55
LRR_13
Arf
Beta-prop_EML_2
LRR_6
T2SSE
nSTAND3
AAA_22
LRR_LRWD1
AAA_16
AAA_18
FtsK_SpoIIIE
TrwB_AAD_bind
AAA_7
G-alpha
NACHT
ABC_tran
SRPRB
cobW
MMR_HSR1
WD40_Prp19
Motif
Other DBs
NCBI-GeneID:
134310092
NCBI-ProteinID:
XP_062847682
LinkDB
All DBs
Position
1:33150667..33207658
Genome browser
AA seq
2537 aa
AA seq
DB search
MVNKQDLEESLKKLLVRLRNNLEEGRQLGSMVQIVQDLLFLAHTDDCEELFKDKNVHEPL
MLVLTSCSNSKLQQVGLSLLCRLMEICPATLDKLVYPLQAGKDWEVLGVHKQILKVLTNY
HKDFKVIIVALRALALLLRSDELALLVLEEDLDVFELVVESMKEFSHSEELQLQGCSALH
LLLERVPEEHLQEFIERKDHTVVLSVLSRFKDSENVVLAALQTLIPLAGPASNVEILMSK
TEKCYSLVCQALEACSQSEAVQETGCCLLQKFTSESYFNILVLNDVHRVAVQACLSYPKN
AKIQAAALSCLAALTKTIVDNKGLERHSSEDEDVVEGINREEEENVEEEGLVWREACCTA
LERHADNVVVQEAACWALNSLLLYGSARNHIYMESKDRPPVHIHLITVMLHSSSVGVFQA
AATTLSTLIRRHSKMRSNLLSCGIHYNIVELMKKHALSSTVCESACRLLFTLFQGGRRMS
LDEGTMALGQILIAMKDHSFLPEVQLEGLRASLVLLNPDRSLREEGTSVADPDTLDVSLK
VLKNQCVIEGAHAVYLEALNRFISSEEIQECGLVVLTALADCSGAVDLMCQQGAIDTVLH
TLQMFPHKRDIHYWALSLLYHLMSKKKLLHMMVRVLVSVLIVSVRQHKEDAEMLHKGFQV
LWKLLDTCPNAAAELDKEGFEKEIFQQLRESSSDKRYDPLQKLSRMCLSKMAVDSEICYR
LLERACEERDVVMAECLIHLGADVNKKTKTESLIYQVCERGGPLPLVELLVSSGVHEQQL
RGALSVCVRERDGPLVVLLLARLGLDHTNNALCLGGFRLGHLEATWLSALLSERRAPPTT
PKRNSKGQCLARWIKSMQNRRSHVVSCPGYYSDEGSDDSSYTSLDDSVFLTLEDSDGSDS
SVWGMRSFCDSPELRGRSKTRQEGQRRRASSEARSDVPDVTDSFSNRLNKNGIFQRGMIF
SESSSPGGLLSSMDRDRIRLLDLSGNELNSLLCLMDDSVVLQQLEHLLHLDLSSNSLSEF
PPALCESLRSLTRLDLQGNQLHTLPAELLSLPSLSMLNVSQNSVGPELCLDPYVCCPCLR
QLNLSYNNITAFPYQLGKAMENLRELSLEGNQISELSLPLSLPELKVLDVSKNNLMMISD
DVLSLCIKLETFSASNNKLSYLSPLPSKLTTLKLSRNNYKSVPEAIVNLPNLRSLDMTNN
SITVLPGPEIWGSANLRELMFSKNQISVLELREPVFKWARLEKLHLSDNKLTELPPQIGL
LEELTSLDVSGNEGLHSFPDEIGKLGRLWDLPLDRLQLQMDLKLIGNKTKDIVRYFQHRL
KKAVPYYRMKLIVVGTTGSGKTTLIHQLMKLKRSQWYCGTHISSITIKDWTIRNYKKNMV
LNFWDFSGGEKYSGSHPHFMSSRALYLVLYDLSKGVSELDAVRPWLFNIKALAPLSPVIL
VGTHLDECEEGLLLQCEHKLRDEVLSMPGFPTIRENFMLCACEESVLISRLRKVIVREAS
DFKIQGQPVMGQLVPDSYVELERRILQEKNRVLAEFPVLRHQRLIELIEESQLQLEEGEL
AHAIRFLSETGVLLHFDDPAFQLQDLYFIDPQWLCNIITQILTLRSLCESPRGVVQHSVV
ERFLNESRCFPKEQLMQYFKLLEKFQIALPFGDKQLLVPSSLSDNKPVIELPHCENSEII
VRLYEMPYFPMGFWSRLISRLLEFSLLMLSERDKTTRPNRIYWRTGVYLNWSSEAYYLVE
ACLMKNKPVSYVKITVPCSRKGHMLLGQVVDHIDSLLEEWFPGLLATDVHGDGESLLKKW
ACYSFDDTQDWNQMLLEDLLKHIEKDGRLVNPENPHCTIPISQICPDLMLCDQPASIMLN
HEELEMELSKEYLLGDGGFGSVYRAIYRNEDVAVKIFKKHASHYYVHRLLRQELTVLGRL
HHPSLVGLLAAGSFPHLLVMELAPCGSLDSRFEHENGRLNRKLQHRIALQVADGLSYLHS
SMIIYRDLKPHNVLLFSLKADSEIIAKLTDYGISQYCCSMGVKSSEGTPGFRAPEVAHGN
VIYNVQADMYSFGLLLYDLLTCGERISDGVKFPSEFDEIAVQGKLPDPVKHYKCSPWPMF
QSLMKQCLRENPESRLTSAKVFDYLNSGEMLCLNSELTVRGLSSECFTASHSNGGVNGSV
NMGSLSQVWMGSGSSSQGLGRVTCVDVETEKISTLEVDQSPVLCLVTVRVPEQTHDWLVA
GTQRGSLVVMDTRSITVLHCLRSVKDAVTSLFFHTQRSCLKNYLLVGTADGTLVIYEDSV
IKCADGGPVKVVQVGNVNTPLMCVAPSGHHLDRTTLWAGCGTKVLSLTMDYNICKSIDTR
PSFYHKQRIASSEACISRLVVEKFVYLSKNGGHTVEVWDKKTGKMIDFIDCAQLLRSSSN
KKNRAASSDIFREVESSWARVKALLVQHNGTLWIGTRAGIILLVDMTTHQLLQAINSGCH
SVRSMASVLIETQNRRSVVLMLGRRVRKSSDQIKSPLGEDSVLITWSSTMPQEVKDLNRH
TELREQITAKMREQNHD
NT seq
7614 nt
NT seq
+upstream
nt +downstream
nt
atggtgaacaaacaggatttggaggaaagcttaaaaaagctgcttgtgcgactgaggaac
aacctcgaagaggggaggcagttgggcagcatggtccagatcgttcaggatcttctgttc
cttgcacacactgacgactgtgaagaactgtttaaggacaaaaacgtccatgagccactg
atgctggttctcacgtcttgcagcaacagtaaacttcagcaggtgggattgtccctgctc
tgccggctgatggagatctgtcctgccactctggacaagctggtttatcccctccaagct
gggaaagattgggaagttctaggggtgcataagcagattctgaaggtgctgaccaattat
cacaaagactttaaagtaataatagtagcactacgagcgctggccctgctgctgagatcc
gatgagctggcactgctggttctggaggaggacttggatgtgtttgagctggtggtggaa
tctatgaaggaattttctcatagtgaggagctgcagcttcagggctgctctgctctgcat
ctgctgctagagagagttccagaggaacatctgcaggagtttattgaaagaaaggatcat
actgtggttctgagtgtgctcagtaggtttaaggacagtgaaaatgtagtgttggctgca
ctgcagacgcttataccattagctggtcctgcaagcaatgtggaaattctcatgtccaaa
acggaaaagtgctacagcttggtgtgccaggcattggaagcgtgctcacagtcggaggct
gtacaggagacgggatgctgcctgctgcaaaaatttacttcagagagttacttcaatatc
ctggtgctgaacgatgtgcacagagtggctgtacaagcttgtctttcctaccctaaaaat
gccaaaatccaggctgctgctctttcctgtctggctgcactcacaaagacaattgtggac
aataagggtcttgagagacacagcagtgaggatgaggatgtggttgaggggattaacaga
gaggaagaggaaaatgttgaagaggaaggcttggtttggagagaggcttgctgtacagct
ttagagagacatgccgacaatgtagtcgtgcaggaggctgcctgttgggctttaaacagc
ttgctgctttacggcagtgcacgcaatcatatatacatggaatccaaagacaggcctcct
gtacacattcacttaatcactgtgatgcttcactcctcaagtgttggtgtgtttcaggca
gcagcaaccacactgagcacacttatacgtcggcacagtaaaatgaggtccaatctgctg
agctgtggtattcactacaatattgtagaacttatgaagaaacatgcactctccagcaca
gtgtgtgagagtgcttgcagacttctcttcacactttttcaaggaggcaggaggatgagt
ctggatgaagggaccatggctctgggtcaaatcctgatcgccatgaaagatcatagcttt
ctgcctgaagtacagcttgagggactaagagccagtctggtgctcctcaacccagaccgc
agtttgagggaggaaggtacatctgtagcagatccagacactttagatgtatctttgaaa
gttttgaagaatcagtgtgtgatagagggagcacatgctgtttacctggaagccctaaac
aggttcatcagcagtgaggagatccaagagtgtgggcttgttgttctgacagctttggct
gattgctctggagctgttgatctcatgtgccaacagggggcgatagatacagtgctgcac
acactacagatgtttcctcacaaacgagatatccattactgggctctaagcctcctgtat
catctcatgtcaaagaagaagctcttacatatgatggtgcgcgtgctggtatctgttcta
attgtctctgtgagacagcataaagaggatgcagagatgcttcacaaaggttttcaggtg
ctgtggaagctgttggacacatgtccaaacgcagcagccgagctggataaagagggcttt
gagaaggagatcttccaacagttgagggaaagctcttcagataagagatatgatccactg
caaaagcttagccggatgtgtctgtcaaagatggcagtggacagcgagatctgttaccgg
ctactagaaagggcatgtgaggaaagggatgtggtcatggctgagtgtcttatacatttg
ggagctgacgtcaataaaaaaaccaagacagagtctttgatatatcaggtgtgtgagcgt
ggtgggccactgccgttggttgagctgctagttagcagtggtgtacatgagcaacagctg
cgaggcgctctgagcgtatgcgtgagagaacgagacggaccactggtcgtccttctgctg
gctcgactgggtctggaccacaccaacaacgctctgtgtctgggagggttcaggcttgga
catttggaagccacatggcttagtgcacttctgtcggagcgcagagctccccctactacc
ccgaagaggaatagtaaggggcagtgtctggccagatggataaagtccatgcagaatagg
agaagtcatgttgtgagctgtcctgggtattactctgatgaggggagtgatgactcctct
tacacctcactagatgacagtgtgtttcttacacttgaagacagcgatggaagtgacagt
tctgtttgggggatgagaagtttctgtgattcaccggagctgagggggcgatctaaaaca
aggcaagagggtcagcgaagacgtgcttcctctgaggcaaggagtgatgttcccgacgtt
accgattccttttcaaataggttgaacaagaatggcatatttcaaagaggaatgattttt
tcagagagctcttcccccggtggtttactgtcaagtatggacagagatcgtattagactg
ctggatctgtcagggaatgagctgaactctctgttatgcttgatggatgacagtgtagtt
ctgcagcagcttgagcatctattacatcttgatctgagcagcaacagcctgtcagagttt
ccccctgctctctgtgagagcttgagaagcctcactcgactggatctacaaggcaaccag
ttgcacacacttcctgctgaactgctgagcctaccctcattaagcatgctcaacgtctca
cagaactccgttggtccagagctctgtttggacccatacgtgtgctgtccgtgtctgcgg
cagcttaacctttcctacaacaacatcactgcctttccataccagctgggcaaagccatg
gaaaaccttcgtgagctctcactggaggggaatcaaatctctgaactctccttacctctc
tctctccctgaactgaaagtgttagatgtatccaaaaataatttaatgatgatctctgat
gatgtcctgtctttatgcattaagctggaaacattcagcgcctccaacaacaaacttagt
tatttgtcaccactgccatctaaattaacaacactgaaattatcccggaacaattataaa
agtgtgcctgaagcaatcgtcaacctaccaaatttgcgatcgttggacatgacgaataat
agtatcactgtcctgcctggtccagagatctggggcagtgctaatctgagagagctgatg
ttcagcaagaaccagatatctgtgctggagctgagagaacctgtttttaagtgggctcgt
ctggagaagctgcatctgagtgataacaagctcactgagcttccccctcaaattgggctg
ctggaggagttgacctcattagatgtgagtggtaatgagggcctgcattcttttcctgat
gaaattggtaagctggggcggctgtgggatttgcccctggacagacttcagcttcagatg
gaccttaaacttattggaaacaagaccaaagacattgtcaggtactttcagcaccgccta
aagaaggctgttccatattaccggatgaagctgatagtggtgggaactacaggcagtgga
aagaccacactgatccatcagctaatgaagctcaaacgttcccagtggtactgtggcaca
catatctccagcatcaccatcaaagactggaccatccgaaactacaagaaaaacatggtc
ttgaacttttgggacttctcaggtggagagaagtacagtggctctcaccctcactttatg
agctctcgagctctctacttggtactgtatgacctgagtaagggagtcagtgagttggat
gcagtcagaccctggctctttaacatcaaagctttagcccctctctcccctgtaattctg
gttggcactcatctggatgagtgtgaagagggtttgttgcttcagtgcgagcataagctc
cgtgacgaagtgctgtccatgcccggtttcccaaccattagagaaaacttcatgctctgt
gcctgtgaggagtccgtcctgatcagcagacttcgcaaggtcatcgtcagagaggccagc
gactttaagatccaagggcagccagtgatggggcagctggttcctgattcttatgttgag
ctggagaggaggattctgcaagagaaaaatcgtgtgcttgctgaatttcctgtgcttaga
caccagcgtcttattgagcttattgaggagagccagctgcagttggaggagggagaactt
gctcatgccattcgctttctaagtgagactggtgtactcctgcactttgatgaccctgca
ttccaacttcaagatttgtatttcatcgatccacagtggctgtgcaacataattactcag
atcctgactctaagaagcctatgtgagagtcccagaggagtggtgcagcactcagtggtg
gagagattcctcaatgagagccgctgttttcccaaggaacagctcatgcagtactttaaa
ctgctggagaagttccaaattgctctgccttttggggataaacaactgctggtgcccagc
agtctgtctgataacaagccagtaattgagcttcctcactgtgagaattctgagatcatt
gtgaggctttatgagatgccctattttcccatgggtttttggtccaggctgatcagccgt
ctgctggagttctccctgttaatgctgtcagagagagataaaactacaagaccaaaccga
atctactggaggaccggggtgtacctgaactggtcttctgaggcgtactacctagtggaa
gcctgtttaatgaagaacaagcctgttagctatgttaaaatcactgtgccctgctcacgt
aaaggtcacatgctattaggccaagtggttgatcatatagactctttgctggaggagtgg
tttcctggtctcctcgccactgatgtacacggggatggggagtctcttctgaagaagtgg
gcttgttacagctttgacgacacacaagactggaatcagatgctgctggaggatctgctc
aaacatattgagaaagatggtcggttggtgaatccagaaaaccctcactgtacaataccc
atctcacaaatatgccctgatctaatgctgtgtgaccaacctgctagtatcatgctgaac
catgaggagcttgagatggagctttccaaagagtacctgcttggtgatggaggctttggc
tcagtgtacagagcaatatacagaaatgaagatgttgctgtgaagatttttaagaagcac
gcttcccattattatgttcatagactactaagacaggagctgacagtgttgggcaggctg
catcaccccagtctggtgggtctgctggctgcagggagctttcctcatctactagtgatg
gaactggcaccatgcggttctcttgactcacggtttgaacatgagaatggcagattgaac
cgcaaactgcaacatagaatagcattgcaagtggctgatggcctcagttatttgcactct
tctatgataatctaccgggacttaaaacctcacaatgttctgctgttcagtttgaaggct
gactctgagataatagcaaaactgactgattatggcatctctcagtactgctgcagtatg
ggagtcaagagctctgagggcactccaggtttccgggcacctgaggttgctcatggaaat
gttatttataacgttcaggcagacatgtattcttttggtttgctcctatatgatcttttg
acgtgtggagaaagaatatcagatggagtgaagtttcccagcgagtttgatgaaatagct
gtgcagggaaaactaccagacccagttaagcactacaaatgttctccatggccaatgttt
cagagtctgatgaagcaatgtctgagggaaaacccagagagcagactcacctctgcaaag
gtgtttgactatttaaactcgggggagatgctttgtctgaatagtgagctgacggtgcgt
gggctgtctagtgagtgtttcactgcgtcacatagcaatggaggtgtaaatgggagtgtg
aacatgggttcattgtctcaagtttggatgggaagtggcagtagcagccaggggctcggc
cgtgtcacgtgtgttgatgtagagacggagaaaatttccacactggaggttgaccaaagt
cctgtgctctgcctggtgactgtcagagtacctgaacagacccatgactggctggttgct
ggaacacagcgcggatcactagtggttatggatacaaggagcattacagttttgcactgt
ttgcgaagtgtaaaggatgcggtgacctcgttgttctttcacactcagcgcagctgtttg
aagaactacttattagtgggaactgcagatgggactcttgtcatttatgaggattcagta
ataaagtgtgctgatggtggtccagtaaaggtggtgcaggttgggaacgtgaacactcct
ctgatgtgtgtggctccatcaggtcaccatctggaccgtaccacgctgtgggctggctgt
ggcaccaaagtgctgtcactaactatggattacaacatctgcaagagcattgacaccagg
cccagcttctatcataagcagcggatagccagcagcgaggcatgtatctctcgactagtg
gtggagaagtttgtgtatctcagtaaaaatggaggacatactgtggaggtgtgggataaa
aagactgggaagatgattgacttcatcgactgcgcacagttactcaggtccagctcgaac
aagaaaaacagggctgccagttctgacatttttagagaggtggagtcatcatgggctcga
gtaaaggcactgttggttcagcacaatggcacgctatggatcggtaccagagctggaatc
atcctgctggtggatatgactactcatcagctactacaggccatcaattccggctgccac
tcagtgcgcagtatggcctctgtactcattgagacacagaacagaagaagtgtggtcctg
atgttgggcagacgcgttcgcaagtcttcggaccagatcaagtctccgttaggtgaggac
tcagtgctaataacgtggagtagcactatgcctcaggaagtcaaggatctgaacagacac
actgagctaagagaacagattacagccaaaatgagagaacagaaccatgactaa
DBGET
integrated database retrieval system
