KEGG   Thermomicrobium roseum: trd_0229
Entry
trd_0229          CDS       T00845                                 
Symbol
rfbB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
tro  Thermomicrobium roseum
Pathway
tro00521  Streptomycin biosynthesis
tro00523  Polyketide sugar unit biosynthesis
tro00525  Acarbose and validamycin biosynthesis
tro00541  Biosynthesis of various nucleotide sugars
tro01100  Metabolic pathways
tro01110  Biosynthesis of secondary metabolites
tro01250  Biosynthesis of nucleotide sugars
Module
tro_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:tro00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    trd_0229 (rfbB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    trd_0229 (rfbB)
   01055 Biosynthesis of vancomycin group antibiotics
    trd_0229 (rfbB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    trd_0229 (rfbB)
   00525 Acarbose and validamycin biosynthesis
    trd_0229 (rfbB)
Enzymes [BR:tro01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     trd_0229 (rfbB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 NAD_binding_4 adh_short NmrA Sacchrp_dh_NADP KR
Other DBs
NCBI-ProteinID: ACM06140
UniProt: B9KXP2
LinkDB
Position
240059..241093
AA seq 344 aa
MSDAVFRRILITGGAGFIGSHFVRLALAAGIPSVVVLDKLTYAGSLLNLEEVLDDPRVRF
LEGDIADPAAVAEAMAGCDAVVNFAAETHVDRSLLEPAAFIRTNVWGTMVLLEQALRLGV
GRFLHVSTDEVYGEVLSGSVSEDEPLRPRNPYAASKAAAEHFVFAYWTSYGLPVLVTRGC
NTYGPYQHPEKFIPLAITNLLTGRPIPLYGDGLHERDWLYVEDHCRAIWTVLVRGEPGQA
YNIGAGQHRPNIAVARALVRLLGADPSAIVHVADRPGHDRRYAVDWSRLRALGWRPMVDF
EDGLARTVAWYRARTDWWSARRDAAFAAYYARNYQGREGYRNQP
NT seq 1035 nt   +upstreamnt  +downstreamnt
gtgagcgacgcggtgttccgacgcatcttgataaccggcggggctggcttcatcgggagt
cacttcgtccgtctcgcgctcgcagctggcatcccgagcgttgtcgttctcgacaagctc
acctatgccgggagtcttctgaacctggaagaggtgctcgacgatccgcgtgtccgtttc
ctcgagggagatatcgctgatccagcggcagtggccgaagcgatggccggctgcgacgca
gtggtcaatttcgcggccgagacgcatgtggatcgctccctcctggagccggcggccttt
atccggacgaacgtgtggggcaccatggtgcttctcgagcaggcgctccggttgggtgtc
ggtcgttttcttcacgtgagcactgacgaagtctacggtgaggtgctcagcggttcagtc
agcgaggacgagccgctgcggccccgcaatccctacgcggcgagcaaggcagccgcagag
cacttcgtcttcgcctattggacgagttacggcctccccgtgctggtgactcgtggctgc
aatacctacggtccttaccagcatccggaaaaattcattcccttggccatcaccaatctt
ctcactggccgaccgatccctctctatggtgacggactgcacgagcgcgactggctctac
gtcgaggatcactgccgagccatctggaccgtgctggtgcgcggtgagcctggtcaggcc
tacaacatcggagcagggcagcatcgaccgaacatcgcggtggcgcgagcgttggttcgt
ctgctcggcgccgacccgagtgccatcgtgcatgtcgccgatcggcccggacacgatcgg
cgctatgccgtcgattggagtcgcttgcgggcgctgggctggcggccgatggtcgacttc
gaggacggtttggcgcggacggtcgcttggtatcgggcgcggacggattggtggtcggca
cgccgcgatgccgcgttcgccgcgtattacgcgcgcaattaccagggacgagaaggatac
cgcaaccagccgtga

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