KEGG   Thermomicrobium roseum: trd_0365
Entry
trd_0365          CDS       T00845                                 
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tro  Thermomicrobium roseum
Pathway
tro00290  Valine, leucine and isoleucine biosynthesis
tro00620  Pyruvate metabolism
tro01100  Metabolic pathways
tro01110  Biosynthesis of secondary metabolites
tro01210  2-Oxocarboxylic acid metabolism
tro01230  Biosynthesis of amino acids
Module
tro_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tro00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    trd_0365
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    trd_0365
Enzymes [BR:tro01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     trd_0365
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2
Other DBs
NCBI-ProteinID: ACM05033
UniProt: B9KY22
LinkDB
Position
366185..367873
AA seq 562 aa
MTMRRPPRRGEAAERFREGRRERMSENGERRVVIYDTTLRDGTQGSGVSLTTEDKLKIAR
ALDELGVAYIEGGWPGSNPKDMAFFERARHQQWRHARITAFGSTRRAGGTVEEDVNLRLL
LEAETPAVTIVGKASPFQVRVILGTTLDENLRMVAESVAFLKAAGREVIFDAEHFFDGYA
EDPDYALAVLRAACDAGADAVVLCDTNGGTLTDPLVRAVRHALSSVSCTVGIHTHNDCEL
AVANTIAAVLAGAMHVQGTMNGLGERIGNANLCSIIPILEYKLGYRCLPPGNLRKLTETS
RYVAEVANLAHDPRLPFVGAFAFTHKAGLHVNAIAKHPSAYEHIPPEVVGNTRHVLVSEL
SGRSNIVVKARSFGIELGDKPEVVRRVLEQIKELEFHGYWFEDADASLELLIRRNLPDYR
PPFEVLDYTVLTEYRNGRGMLAEAMVKLRIGQHVFHTAAEGNGPVNALDRATRKALQEFY
PEIAAVDLEDYKVRVLDDHHGTGAKVRVWIRSGDAHGSWNTVGSSENIIEASWLALADSL
AYPLVTRPELAARIPELVSAVS
NT seq 1689 nt   +upstreamnt  +downstreamnt
atgacgatgaggcggcctccccgacgcggggaggccgccgagcgtttccgagaaggaagg
agggagcggatgagcgagaacggcgaacgacgagtggtcatctacgatacgacgttgcgg
gatgggacgcagggatccggtgtctccctaacgacagaagataaattgaagatcgcccgg
gcattggacgaactgggtgtggcctatatcgagggtggctggcccggctccaatccgaag
gacatggcgtttttcgagcgtgcccgacaccagcagtggcgacacgccaggatcactgcc
ttcggaagcacacgccgagccggcggaacggtcgaagaggacgtcaacttgcgtctcctg
ttggaagcggagacaccggcggtgacgatcgtcggcaaagcgtcaccgtttcaagtgcgc
gtaatcctcggcacgaccctcgatgagaatctccggatggttgcggaatcggtcgccttt
ctcaaggcggcaggacgcgaagtgatcttcgatgccgagcacttcttcgatgggtatgcg
gaggatccggactacgcgctcgccgttctacgggcggcctgcgatgctggcgcggacgcg
gtggtgctgtgcgacaccaacggtggaacactgacggacccactcgtgcgggcagtgcgg
catgcgctctcctcggtctcctgtactgtgggcattcacacacacaacgactgcgaactg
gctgtcgccaacacgatcgccgcagttctggctggtgccatgcatgttcaggggacgatg
aatgggctcggggaacggatcgggaacgccaatctctgttcgatcatcccgattctcgag
tacaagctgggctatcgctgcttgccgccgggtaatctgcgtaagctcaccgagacgtct
cgatacgttgcggaggtcgccaacctggcgcacgatcctcgcctcccattcgtgggagcc
ttcgcgttcacgcacaaggccggactgcacgtgaatgcgatcgccaagcacccctcggcc
tacgagcacattccgccggaagtagtgggcaatactcggcacgtcctcgtcagcgaactg
agcggtcggagcaacattgtcgtgaaggcgaggagcttcggcatcgagctcggcgacaag
ccggaggtcgtgcgacgtgtcctggagcagatcaaggaactcgagtttcacggttattgg
ttcgaggacgctgatgcatcattggaactcttgatccgccgcaacctgcccgactaccga
ccaccgttcgaggtgctcgactatacggtcctgaccgaatatcgcaatgggcgcggcatg
ctcgctgaggcgatggtgaagttgcgcatcggccagcacgtcttccacaccgcggccgag
ggtaacggaccagtgaacgccctggaccgggctactcgcaaggcgctgcaggagttctat
ccggagatcgctgcggtagacctcgaggactataaggtacgcgtcctcgatgatcatcac
ggaacgggcgcgaaggtgcgcgtctggatccgctccggtgacgcgcatggcagttggaac
acggtcggttcctcggagaacatcatcgaggcgtcctggttggcattggctgatagcctg
gcctatccgctggtgacccggccagaactcgccgctcgcattcctgagctcgtatcagct
gtttcgtga

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