Thermomicrobium roseum: trd_0749
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Entry
trd_0749 CDS
T00845
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tro
Thermomicrobium roseum
Pathway
tro00230
Purine metabolism
tro01100
Metabolic pathways
tro01110
Biosynthesis of secondary metabolites
Module
tro_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
trd_0749 (purL)
Enzymes [BR:
tro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
trd_0749 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACM05316
UniProt:
B9KZ38
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Position
737695..739896
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AA seq
733 aa
AA seq
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MPIVPEILREVALTEEEYARAVALLGREPNLIELGMIGALWSEHCGYKHSRPLLRKLPTS
GPHVVQGPGENAGAVELGDGLVVVLKIESHNHPSAVEPFQGAATGVGGIVRDIFAMGARP
IALADSLRFGPLEEPRQQYLFHGVVGGIGWYGNCLGIPTVAGDVFFAPEYRQNPLVNAMC
VGIAERSALIRARATGPGNLVVLVGADTGRDGIHGATFASVEDPERSHRGVVQVGNPFLE
KLLLEACLEVLETGAVVAMQDLGAAGLTSASAEIAARGGTGIELDVALVPRRETGMTPYE
VMLSESQERMLLVVDPEGIDRVLAIFRRWELHAVVIGRVTDDGLLRVLEDGQVVAELPVW
LLTDACPTYVREAREAGEIRERRAFDPDALPDLQPAEVAEMLAALLRSPNIASRRPIYRT
YDHTILTNTVLPPGAADAAVLRIKGQRFGIALKTDCNPRYCLLDPRLGTMHAVAEAARNV
SCVGAEPLAITDCLNFGNPERPEIYYQLVQAIEGMAEACTVLGIPVVSGNVSLYNETEGR
SIPPTPVVGIVGRLADVRRCVGMGFRGEGKVFLLGSELATLGGSEFLAQRHGLVAGAPPP
LDLELERRVQACVREGIARGIVLAAHDCSEGGLLIALAESCMVGRIGGRFTTESLIAANG
RLDRALFGESASRVIVQVAEGAEGALLGLARAHGVPVQELGRTGGDRFVVGELVDQPLSE
LIELWTTGLVESA
NT seq
2202 nt
NT seq
+upstream
nt +downstream
nt
atgccgattgttccggagatcttgcgtgaggtcgcactgaccgaggaggagtacgcgcgt
gcggtcgcgctactcggacgagagccgaacctcatcgaactcggcatgatcggtgcgctg
tggagtgagcattgtggctacaagcattcccggccgctgctccgcaaactgccgacgagc
gggccacatgtcgtgcaagggccgggggagaacgcgggagcagtcgaactcggtgatggg
ttggtggtcgtgctcaagatcgagtctcacaaccaccccagcgcggtcgagccgtttcag
ggagcggcgaccggcgtcggagggattgtccgcgacatctttgccatgggagcacgaccg
atcgcattggcggattcgctccgcttcggaccgctggaagagccgcgtcaacaatatctt
ttccacggcgttgtcggaggtattggctggtacgggaactgtctgggtattccgaccgtg
gcaggggatgtcttcttcgcgcccgagtaccggcagaatcccttggtcaatgcgatgtgt
gtcgggatcgctgaacgctcggccttgatccgggcgcgtgcgaccggaccaggcaacctg
gttgtcctggtcggggcagacaccggacgggacggcattcacggcgcgacttttgcatcg
gtcgaggatcctgaacgctcgcatcgaggggtcgtccaggtcggtaacccatttttggag
aagctcctgctcgaagcatgcctggaagtgctggagactggtgcggtggtcgcgatgcag
gatctcggcgcggcgggcttgaccagtgcgagtgcggaaatcgcggcacgcggtgggaca
gggatcgagctcgatgtggcactcgtaccgcgccgggagaccggaatgacgccgtacgag
gtgatgctctccgagagtcaggaacggatgctcctggtcgtcgatcctgagggaatcgac
cgtgtgctcgcgatcttccggcgctgggaactccatgcggtcgtcattggccgggtgacg
gatgatggactgctccgggtgctcgaggacgggcaagttgttgctgagctgccggtctgg
cttctcaccgacgcttgcccgacttatgtccgcgaagctcgcgaagcgggtgagatcagg
gagcgtcgtgccttcgatccggatgcgctacccgatcttcagcccgccgaagtagccgaa
atgctcgcggcactgcttcgttcgcccaatatcgcgtcgcgtcggccgatctatcgtacg
tatgaccacacgatcctcaccaacacggtgctgccgcctggtgcggccgatgcggcagtg
ctccggatcaaagggcaacgattcgggatcgcgctgaaaacagactgcaatccccgctat
tgcctgctcgaccctcggctcggtaccatgcacgcggtcgctgaggcagcgaggaatgtc
agctgtgtcggagcagagccgctggcgattaccgattgtctcaacttcggtaatcccgag
cggccggagatctattaccagctcgttcaggccatcgaaggaatggcggaggcctgtacg
gtactcggtattcccgtcgtgagtggaaatgtcagtctctacaacgaaacggaagggcga
tccatccctcctacgccggtcgttgggatcgtcggtcggctggccgacgtgcggcggtgt
gtcggtatggggtttagaggtgagggaaaagtctttctgctcggttcagagctggcgacg
ctcggcggttccgagttcctcgcccaacgtcatggactggttgccggtgccccaccgccg
ctcgatctggaactggagcgacgagttcaagcatgcgtgcgggaggggatcgctcgtgga
atcgtcctggctgcccacgactgcagcgagggaggcttgctcatcgcactggccgaatcc
tgcatggtcggacggatcggcggtcgcttcaccaccgagtcactcatcgccgccaatggg
cgattggaccgggcgctcttcggagagagcgcatcgcgcgtgatcgttcaagttgctgag
ggggccgaaggagcgttgctggggctggcacgggcccacggggtaccggtacaggaattg
gggcggacgggtggagatcgcttcgtcgtcggtgagctggtcgatcagccgctcagcgag
cttatcgagctgtggacgaccggcttagtggaatcggcgtga
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