Thermomicrobium roseum: trd_1693
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Entry
trd_1693 CDS
T00845
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
tro
Thermomicrobium roseum
Pathway
tro00290
Valine, leucine and isoleucine biosynthesis
tro00660
C5-Branched dibasic acid metabolism
tro01100
Metabolic pathways
tro01110
Biosynthesis of secondary metabolites
tro01210
2-Oxocarboxylic acid metabolism
tro01230
Biosynthesis of amino acids
Module
tro_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
trd_1693 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
trd_1693 (leuB)
Enzymes [BR:
tro01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
trd_1693 (leuB)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
ACM04721
UniProt:
B9L0Y3
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Position
1695697..1696818
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AA seq
373 aa
AA seq
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MSEVHVLLLPGDGIGPEVVAAAQRVLELVGHRTGYRFVFSEDLVGGAAIDAYGTPLRDET
IEMALRSDAVFLGAVGGPKWDHLPKATRPEAGLLRLRKELGLFANLRPVRVFDPLADATP
LKPEIVRGVDLIVVRELTGGLYFGQPSELRREPTGRWAIDTLPYREEEIARIVDLAFQLA
RARRRKVTSVDKANVLNTSALWREVASEIGQRYPDVTLEHALVDSCAMRLVARPRDFDVL
VMENLFGDILSDEAAVLAGSLGMLPSASLHGQPPQRPGSPAVRFGLYEPVHGSAPDIAGK
GIANPIGAILSAALLVRWTLGNERAATAIEQAVEETLASGARTADLARPGEPAMGTEAFT
DRLLERLASILSA
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaggtgcacgtgctcctcctgcccggcgacggtatcggcccagaggtggtcgcc
gcagcccagcgtgtcctcgaactggtcggccaccggactggttatcgtttcgtcttctcg
gaggacctcgtcggtggggcagcgatcgatgcctatggcacgccgctccgcgacgagacg
atcgaaatggcgcttcgctccgatgccgttttcctcggggcggtcggtggccccaagtgg
gatcatctcccaaaggccacacgcccggaggccggtctcttgcgcttacggaaggagctc
gggctcttcgccaacctgcggccagtacgcgtcttcgacccgctcgccgatgccacgccg
ctcaagccggagatcgtgcgcggcgtcgaccttatcgtggtccgcgagctgaccggggga
ctctacttcggtcagccgtccgagctgcgccgcgagccaactggccgctgggcaatcgac
acccttccctatcgagaggaggagatcgcgcggatcgtcgacctcgcgttccagcttgcc
cgggcacgtcgccgcaaggtgacgagcgtcgacaaggcgaatgtactcaacacctcggcg
ctgtggcgcgaagtcgccagtgagatcggtcagcgctacccagacgtcacgctcgagcat
gccctggtcgattcctgcgcgatgcgtctggtcgcccggccgcgcgatttcgacgttctc
gtcatggagaatctcttcggcgacatcttgagcgacgaggcagcggtcttggccggctcg
ctcggcatgctcccttcggcgagcttgcacgggcagccaccgcaacggcctggctcgccg
gcggtccgcttcgggctgtacgaaccggtgcatggctcggcacctgacattgctggcaag
gggatcgccaatcccatcggcgccatcctgagcgcggccctgctcgttcgctggacactg
gggaacgagcgcgctgcgacggcgatcgagcaggcagtcgaggaaacgctcgcctccggt
gcacggacggccgacctggcccgtcctggagagccagccatggggaccgaggccttcacc
gatcggttactggagcgactcgcgtcgatcctttctgcctga
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