Takifugu rubripes (torafugu): 101071196
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Entry
101071196 CDS
T02386
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tru
Takifugu rubripes (torafugu)
Pathway
tru00270
Cysteine and methionine metabolism
tru00480
Glutathione metabolism
tru01100
Metabolic pathways
tru01240
Biosynthesis of cofactors
tru04216
Ferroptosis
Module
tru_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
tru00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101071196 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101071196 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101071196 (gclc)
Enzymes [BR:
tru01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101071196 (gclc)
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GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
101071196
NCBI-ProteinID:
XP_003964217
Ensembl:
ENSTRUG00000015144
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Position
4:complement(13381806..13388213)
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AA seq
630 aa
AA seq
DB search
MGLLSVGSPLNWEETKKYADHIRKHGIIQFLNIYNKVKERQKDVLKWGDEVEYMLVEFDD
EEEKVRLTLNSGHLLETLQDQGERINPNHPTLWRPEYASYMIEGTPGQPYGGTMSEFNTV
EGNMAKRRREASSLLDHNQTLCTITSFPRLGCPGFTKPEYRPSPVESRVAKSLFFPDEAI
NKHPRFSNITRNIRHRRGEKVVINVPIFKDKCTPSPFVEEFPEDDGEAAKAALPDHIYMD
AMGFGMGNCCLQVTFQACSINEARYLYDQLATFCPIVMALSAASPFYRGFVSDIDCRWGV
ISASVDDRTPEERGLMPLKHNKYRIFKSRYDSIDSYLSTCGEKYNDIDLTIDEEIYAQLL
DAGIDKLLAQHIAHLFIRDPISVFKERLNLDDENDSDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
LEGMFYFRKDIFKGCNPVLDGSGSAQNGLEGECANEEYTLMSIDNIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTTAKWMREFVANHPQYKEDSVITDKI
NYDLMVKCNQIAKGDEMCPELIGNPVNKFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcagtgggctctccgcttaactgggaggaaaccaagaagtatgccgac
cacataagaaagcacggcatcatccagttcctgaacatctacaataaggtgaaggagcgg
cagaaagatgtgctgaagtggggcgatgaggtcgagtacatgttggtggaatttgacgac
gaggaagaaaaggttcggctcacgctgaacagcggacatcttctggaaaccctccaagac
caaggggaaaggataaaccccaatcacccgacgctctggagaccggagtacgccagctac
atgatcgaaggaactccaggacagccttacggcggcaccatgtcagagttcaacaccgtg
gagggcaacatggcgaagagacggcgagaggcctcttctctcctggaccacaaccaaacc
ctctgcaccatcacctcctttccaaggttaggttgtccaggttttaccaagccagagtat
cgaccaagtcccgttgaaagcagagtggccaagtcgctctttttcccagatgaagccatc
aacaaacacccaagattcagtaacattaccagaaacattcgtcacagaagaggagagaaa
gtggtgataaatgtccccatcttcaaagacaagtgcactccatctccatttgtggaggag
ttccccgaggacgacggggaagctgccaaggcagcgctgcctgatcacatctacatggac
gccatgggcttcggcatgggcaactgttgcctgcaggtgacattccaggcttgcagcatc
aatgaggcaagatacctttatgaccagctagcaacattctgcccaatagtgatggcgctg
agcgccgcctcgcccttctacagaggctttgtgtcggacatcgattgccgctggggagtt
atctctgcatcggttgacgaccggacgccggaggaacgggggctaatgcccctgaaacac
aacaaatacaggatcttcaagtcgagatacgactccatcgacagctacctgtcgacctgc
ggggagaagtacaacgacatcgatttgaccatagacgaggagatctacgcacagctgctt
gacgcaggaatcgacaagctgttggcgcagcacatcgctcacctgttcatccgagatccc
atctccgtctttaaggagagactcaacttggatgacgagaacgactccgatcatttcgag
aacctgcagtccaccaactggcagacgatgaggttcaaaccgccgcctcccaactctgat
atcggctggagggtcgagttccgccccatggaggtgcagctgaccgactttgaaaacgct
gcctatgtggtctttgtggtcctgctcaccagagtgatcttatcctacaaactggacttc
ctgattcctttgtcaaaggtcgacgagaacatgaaggtcgcccagaagagaaacgctgtc
cttgaggggatgttttacttcagaaaggatatctttaaaggttgcaacccggttcttgac
ggctctggttccgcccaaaacggcctggagggggagtgtgctaatgaggagtacacgctg
atgagcatcgacaacatcatcaacggaaaggagggggtgttccagggactcattcccatc
ctcaactgctacttggagaacatggaagtcgacgtggacacccgctgcacgattttaaac
tatctgaagctcatcaaaaagcgtgcctcaggagagctgatgaccacggccaagtggatg
agggagtttgttgccaaccatccgcagtataaggaggacagcgtcataacggacaagatc
aactacgacctaatggtgaagtgcaaccagatcgccaagggcgacgagatgtgcccggag
ctcatcgggaaccctgtcaacaagtttaaatga
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