KEGG   Thiothrix subterranea: HMY34_07910
Entry
HMY34_07910       CDS       T07831                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tsb  Thiothrix subterranea
Pathway
tsb00290  Valine, leucine and isoleucine biosynthesis
tsb00620  Pyruvate metabolism
tsb01100  Metabolic pathways
tsb01110  Biosynthesis of secondary metabolites
tsb01210  2-Oxocarboxylic acid metabolism
tsb01230  Biosynthesis of amino acids
Module
tsb_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tsb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HMY34_07910 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HMY34_07910 (leuA)
Enzymes [BR:tsb01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HMY34_07910 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer Nuc_deoxyri_tr2 DUF3515
Other DBs
NCBI-ProteinID: QQZ28686
LinkDB
Position
complement(1609331..1611010)
AA seq 559 aa
MLKQPSTKYKPFPPVVLTDRQWPSRTITHPPIWMSTDLRDGNQALFEPMNVERKMRMFHT
LCDIGFKEIEVAFPSASQTDFDFVRELIEGKHIPADVTIEVLTQAREHLIRRTMESLRGA
RRAIVHVYNATSQPFRDTVFGMSKADVLGMAVSAVELIKHLAADQPETEWVLEYSPETFS
ATELDFAREVCDAVTAAWGATPANPVIINLPATVEMATPNVYADQIEWMHRHLARRDSVI
LSVHPHNDRGTAVAAAELALLAGADRVEGCLFGSGERTGNVDIVTLALNLYTQGIASGLD
FSDINAVARTAEYCTQLPIHPRHPYVGDLVFTAFSGSHQDAIKKGLAVQTPESFWNVPYL
PIDPADVGRSYDSVIRVNSQSGKGGIAYLLESAYGIVMPRRLQVEFSSVVKDHTDQHGCE
VNASDIWGIFAATYLQTAKPVRYCEHHLFEQGNAQGIRLVIERDGIQHELTGTGNGPIDA
AVHALQGAGIRVQVRSYEERSIGASVDAGDAQACAFIELRQAGAGSSAECYGVGIDGNII
TASIKALVSGVNRLVKEVG
NT seq 1680 nt   +upstreamnt  +downstreamnt
atgttgaaacagccttccaccaaatataagccgttcccgcccgtcgtcttgactgaccgc
caatggccgagccgcactattacccatccaccaatttggatgagtaccgatttgcgcgac
ggcaatcaggcgctgttcgagccgatgaatgttgaacgcaaaatgcgcatgttccacacc
ttgtgtgacatcggtttcaaggaaatcgaagtggcgttcccgtccgcgtcgcaaaccgat
ttcgattttgtgcgcgaattgatcgaaggcaaacacatccctgccgatgtcactatcgaa
gtgctgacgcaagcgcgggaacacctgattcggcgcacgatggaatccttacgcggcgca
cggcgggcgattgtgcatgtctacaatgcgacttcccagccgttccgcgacaccgtgttt
ggcatgagcaaggcggatgtgttgggcatggcagtgtcggcagtggaattgatcaagcac
ttggcagccgaccaaccggaaaccgaatgggtgttggaatacagccccgaaacctttagc
gccaccgagttggactttgcccgcgaggtgtgcgatgccgtgaccgctgcatggggtgcg
acacctgcgaatccggtgattatcaatttgcccgcgacggtcgaaatggcaacgccgaat
gtgtacgccgaccagattgaatggatgcaccgccaccttgcccgccgcgacagcgtgatt
ctcagcgtgcatccgcacaacgatcgtggcacagccgttgccgctgctgaattggcgctg
ttagccggggccgatcgggtggaaggttgcttgttcggcagcggcgaacgcactggcaac
gtcgacattgtgaccttggcgttaaacctttacacccaaggcatagcgtccggtttggac
ttttccgacatcaacgcagtggcacgcacggcggaatattgcacgcaattgccgattcac
ccgcgtcacccgtatgtgggcgacttggtgtttaccgcgttttctggctcgcatcaggat
gcaatcaagaaaggcttggcggtgcaaacgccagagtcgttctggaacgtgccgtacttg
ccgattgatccggcggacgtgggccgcagttacgattcagtgattcgcgtcaacagccag
tcgggtaaaggcggcattgcgtatttgctggaaagtgcttatggcattgtgatgccgcgc
cgcttgcaggtcgaattttccagcgtggtaaaagaccacaccgaccaacacggctgcgaa
gtgaacgccagcgacatctggggcatttttgcggcgacgtatttgcaaaccgccaagccc
gtgcgttattgcgaacaccatttgtttgaacagggtaacgcacaaggcatccgcttggtg
attgagcgggatggcattcagcacgaattgacaggtacgggtaatgggccaattgatgcg
gcagttcatgccttgcagggggcggggattcgggtgcaagtgcggagttacgaggagcgt
tctattggtgcaagcgtggatgcgggtgatgcgcaagcctgcgctttcattgaattgcgg
caggcaggcgcgggcagcagtgccgaatgttacggcgtgggcattgacggcaatattatt
accgcgtccatcaaagccttggtcagcggggtgaatcgtttggtgaaggaagtgggttaa

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