Thermus scotoductus: TSC_c08430
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Entry
TSC_c08430 CDS
T01414
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tsc
Thermus scotoductus
Pathway
tsc00290
Valine, leucine and isoleucine biosynthesis
tsc00620
Pyruvate metabolism
tsc01100
Metabolic pathways
tsc01110
Biosynthesis of secondary metabolites
tsc01210
2-Oxocarboxylic acid metabolism
tsc01230
Biosynthesis of amino acids
Module
tsc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tsc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TSC_c08430
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TSC_c08430
Enzymes [BR:
tsc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TSC_c08430
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
TMP-TENI
Motif
Other DBs
NCBI-ProteinID:
ADW21469
UniProt:
E8PNJ4
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All DBs
Position
792398..794050
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AA seq
550 aa
AA seq
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MGVPGRGVRLSEEGHKAAQGDEEMVEILDTTLRDGTQGEGISLSVDDKVAIAKRLAAFGV
HLIEGGWPGSNPKDAEFFQRMKGVDLGEAKLSAFGATRRKGLLPEEDPSVLALLEAETPV
VVLFGKSWTLHVLEALETTLEENLRMIQDTVAFFVRRGKRVVYDAEHFFDGYKEDSGYAL
ATLEAAAEGGADTLVLCDTNGGTLPEEVYAITKAVVERFPHLRIGIHPHNDAELAVANAL
AAVRAGATHAQGTINGYGERCGNLNLTSFLPTLVFKYGIPAIPPERLKGLKELSHFVDER
ANQTPNRRAPYVGESAFAHKAGVHVSAVLKNPRTYEHIPPEWVGNSRRFLVSDVAGRSNL
LAKLQELGVDLSKEEAKRLLDEVKALEYEGYAFEGAEASFYLLAHRLKGGSLPFSVEGFS
VFVHGSGLDTAWAEATVRVRVGESLQHTAAESPSGPVSALDRAFRKAVLQFYPELSDVEL
TDYKVRILSGQESGTNSGVRVMIEMKRGEERFATVGASENILEASLKALTDGYAYALLYP
SLKEMVPRAG
NT seq
1653 nt
NT seq
+upstream
nt +downstream
nt
gtgggggttccaggaaggggagttcggcttagcgaggaagggcataaggctgcccaaggg
gatgaagagatggtggagatcctagacaccaccctcagggacgggacacagggggaaggc
atcagcctttccgtggacgacaaggtggccatcgccaaacgcctggcggccttcggcgta
cacctcatcgagggaggttggccggggtccaatcccaaggacgccgagtttttccagcgc
atgaagggggtggacctgggagaggccaagctttccgccttcggggccacccgcaggaag
gggcttttaccggaggaggacccttcggttctggccctgctggaggcggaaaccccggtg
gtggtcctcttcggcaagagctggaccctgcatgtcctcgaggctctggaaaccactttg
gaggaaaacctccgcatgatccaggacaccgtggccttcttcgtccggcgggggaagcgg
gtggtctacgacgccgagcacttctttgacgggtacaaggaggactccggctacgccctg
gccaccctggaggcggcggccgaagggggagcggacaccctggtcctttgcgacaccaac
gggggcaccctgcccgaggaggtctacgccatcaccaaggcggtggtggagcgctttccc
cacctgcggatcggcatccacccccacaacgacgccgagctggcggtggccaacgccctg
gcggcggtgcgggcaggggccacccacgcccaaggcaccatcaacggctacggggagcgc
tgcggcaacttgaacctgaccagcttccttcccaccttggtcttcaagtacggcatcccc
gccattccaccggaaaggttaaaggggcttaaggagctttcccacttcgtggacgagagg
gccaaccagacccccaaccgccgggctccctacgtgggggagtcagccttcgcgcacaag
gcgggggtgcacgtctccgccgtcttgaagaacccccgcacctacgagcacattcctccg
gagtgggtggggaatagccgccgcttcctggtgtccgatgtggcgggccgttccaacctc
ctggccaagctgcaggagctgggggtggatctttccaaggaggaggccaagcgcttgttg
gacgaggtcaaggccctggagtacgagggctacgccttcgagggggcggaggccagcttc
tacctcctggcccaccgcctgaagggggggagcctgcccttcagcgtggaggggttttcc
gtcttcgtccacggaagcggcctggacaccgcctgggccgaggccacggtgcgggttcgg
gtgggggaaagcctgcagcacaccgcagcggaaagcccctcggggccggtttccgccctg
gacagggccttccgcaaggcggtgttgcagttttacccggagctttccgatgtggagctc
accgattacaaggtgcgcatcctctccggccaggagtcggggaccaactccggggtgcgg
gtgatgatcgagatgaagcggggggaggagcgcttcgccaccgtgggggccagcgagaac
atcctcgaggcctccttgaaggcccttaccgacggctacgcctacgccctcctttacccg
agcctcaaggagatggtgcccagggcaggctga
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