Thermus scotoductus: TSC_c14460
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Entry
TSC_c14460 CDS
T01414
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tsc
Thermus scotoductus
Pathway
tsc00300
Lysine biosynthesis
tsc00550
Peptidoglycan biosynthesis
tsc01100
Metabolic pathways
tsc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tsc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TSC_c14460
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TSC_c14460
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TSC_c14460
Enzymes [BR:
tsc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TSC_c14460
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADW22063
UniProt:
E8PK32
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Position
1388937..1390223
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AA seq
428 aa
AA seq
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MYLHHVREVTPEWVARATGGRLHPGGKPVRDLHWDSRETTPGSLFVALPGQRVHGREYVD
EARAKGAHLVLSDRPGPATVEVVDTHQALLRLGRALRELFPGQVVAVGGSSGKTTTKEAL
AQGLGFPAPPGNQNTAPPLARFLLRLDPQAPGCVVELGVDRVGEMAELMGLARPHLAVLT
ALGEEHLEAFGSLEGVVEEEAGLLSAPQALVSLQAAEVLERFGLGRGLPTYGFGEATFRG
ENLRLLLHESRFRYGALEVHIPYPGMGPALAALAALGVAEMLGLNPKEVAERLAHLVLPP
GRMERREKDGVVFLNDAYNANPLSVKAGLAWLALQPGRKWVVLGEMRELGEEALRLHLEV
AQEAARLGLKPLYLGPYAKAQASLGGEAAEGLEEAVGWLKERVQPGDLVYLKASRSVGLE
RILELWDA
NT seq
1287 nt
NT seq
+upstream
nt +downstream
nt
gtgtatcttcatcatgttagggaagtaacgccggagtgggtggccagggccaccggggga
aggcttcaccccggggggaaacccgtgcgcgacctccactgggatagccgcgagaccacc
cccggcagcctcttcgtggccttgcccgggcaacgggtccatggacgggagtatgtggac
gaagcccgggccaaaggagcccacctggtcctctccgaccgtccaggacccgccacggtg
gaggtggtggacacccaccaggcccttctccgcctgggaagggccttgcgggagcttttc
cccggccaggtggtggcggtgggaggcagctcgggcaaaaccaccaccaaggaagccctg
gcccaaggcctggggttccccgctccccccggcaaccagaacacggccccgcctcttgcc
cgctttctcctgaggctggatccccaggccccgggctgcgtggtggagctcggggtggat
cgggtgggagagatggccgagctcatgggcctggccaggccgcaccttgcggtgcttacc
gccttgggagaggaacacctggaagccttcggcagcctcgagggagtggtggaggaagaa
gcaggcctgctgtccgccccccaggccctggtgagcctccaggcggccgaggtcctggag
cgctttggcctgggccggggccttcccacttacggctttggcgaggccaccttccgggga
gagaacctgaggcttctccttcacgaaagccgcttccgctacggggccctcgaggtccat
atcccctaccccggcatgggcccggccctggccgccttggccgccttgggggtggcggag
atgctgggcctaaatcccaaggaagtggcggagaggctagcccacctggtgcttcccccg
gggcggatggagcggcgggaaaaggatggggtggtgttcttgaacgacgcgtacaacgcc
aaccccctttcggtgaaagcgggcctggcctggctggccctgcaacccggcaggaagtgg
gtggtcctgggggagatgcgggaactgggggaggaagccctaaggcttcacctggaagtg
gcccaggaagcagcccggctgggccttaagcccctgtacctgggcccctacgccaaggcc
caggcctccttaggcggggaagcagcagagggcctcgaggaagcggtaggttggctcaag
gaacgggttcaacctggggacctggtctacctgaaggcctcgaggagcgtgggcctggaa
aggattctggagctatgggacgcctga
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