Tsukamurella sp. PLM1: MTP03_05610
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Entry
MTP03_05610 CDS
T09545
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tsd
Tsukamurella sp. PLM1
Pathway
tsd00860
Porphyrin metabolism
tsd01100
Metabolic pathways
tsd01110
Biosynthesis of secondary metabolites
tsd01120
Microbial metabolism in diverse environments
tsd01240
Biosynthesis of cofactors
Module
tsd_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
tsd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MTP03_05610 (hemD)
Enzymes [BR:
tsd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MTP03_05610 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MTP03_05610 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BDH55622
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Position
499628..501340
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AA seq
570 aa
AA seq
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MSRTAQSAKAATAADTDTVSTRAAAKTTKPARGRAVAPGRITFVGSGPGDPGLLTLRAQQ
TIAGARTVYTDPDVPQTVLDMVGVELPVEPVEADEDTADASTAKGRKGEPAFRNPATVAP
ALGEPAEVAKTLLAQARHGHDVVRLVAGDPLSSDAVLAEVNAVARTQIVFEIVPGLSPAT
AVPTYAGMALGSAHTEADVRGEVDWAALAAAPSPLVLSATAEHLADTASALVENGLAPQT
PVAVTTQGSTCKQKTVEATLATMGESAAALPGPLVVTVGKIVGQRNKLSWWESRALYGWT
VLVPRTKDQAAEMSNRLRAHGSIPMEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTS
TNAVRAVWEKFIEFGLDARAFSGVKIACVGEQTAAKVRAFGIEPELLPTGEQSSLGMLEV
FPPFDDVFDPVNRVLLPRADIATETLAEGLRDRGWEIDDVTAYRTVRAAPPPASTREMIK
TGDFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLRVDVQPDTASVED
LVEALAAHASRLRAEGALPPPRKKPRRSRS
NT seq
1713 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcactgcacagtccgcgaaggccgccacggcagccgacaccgacacggtgtcc
acccgcgccgccgcgaagaccaccaagccggcccgaggccgggcggtggcgccgggacgt
atcaccttcgtgggttccggcccgggcgatccggggctgctcaccttgcgtgcacagcag
actatcgcgggcgcccgcaccgtctacaccgaccccgacgttccgcagaccgtgctcgac
atggtgggcgtggaactgccggtcgagccggtggaggccgatgaggacaccgccgacgcg
tccaccgcgaagggccgcaagggcgagcccgcgttccgcaaccccgccaccgtcgcgccc
gccctgggcgagccggccgaggtggccaagaccctcctcgcgcaggcgcgccacggccac
gacgtggtccgtctcgtcgcgggcgacccgctgtcgtccgatgcggtgctggccgaggtg
aacgccgtggcccgcacccagatcgttttcgagatcgtcccgggcctctcgcccgcgacg
gccgtgcccacctacgccggcatggcgctggggtcggcgcacaccgaggccgacgtgcgc
ggcgaggtcgactgggcggcgctggccgcggcaccgtcgcccctggttctgagcgcgacg
gccgagcacctggccgacaccgcctccgcgctggtcgagaacggcctcgccccgcagacg
ccggtggccgtcacgacgcagggctcgacctgcaagcagaagaccgtcgaggccaccctc
gcgacgatgggcgaatccgccgctgcgctgccgggcccgctggtggtcacggtcgggaag
atcgtgggccagcggaacaagctgtcctggtgggagtcgcgcgcgctgtacggctggacc
gtgctggtgccccgcacgaaggaccaggccgccgagatgtccaaccggctgcgcgcccac
gggtccatcccgatggaggtcccgaccatcgcggtcgagccgccccgcagccccgcgcag
atggagcgcgcggtgaagggtctcgtcgacggccgctatcagtgggtcgtgttcacttcc
acgaacgccgtgcgcgccgtgtgggagaagttcatcgagttcggcctggacgcccgcgcc
ttctcgggcgtgaagatcgcctgcgtcggcgagcagaccgccgcgaaggtgcgcgccttc
ggcatcgagccggaactgctgcccacgggcgagcagtccagcctgggcatgctcgaggtg
ttcccgcccttcgacgacgtcttcgacccggtcaaccgggtgctgctgccgcgcgccgac
atcgccacggagacgctcgccgaggggctgcgcgaccgcggctgggagatcgacgacgtg
accgcgtaccgcaccgtgcgggccgctccgccgccggcgtcgacccgcgagatgatcaag
accggcgacttcgacgccgtctgcttcacctccagctcgacggtgcgcaacctggtcggc
atcgccggcaagccgcacgcccgcaccatcgtcgcctgtatcggcccgaagacggccgag
accgcgatcgagttcggcctgcgcgtggacgtgcagcccgacaccgcgtcggtcgaggac
ctggtggaggcgctcgcggcgcacgcgtcccggctccgcgcggagggcgccctgcccccg
ccgcggaagaagccccgccgctcgcggtcctag
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