Thiosulfatimonas sediminis: THMIRHAS_10580
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Entry
THMIRHAS_10580 CDS
T06859
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tse
Thiosulfatimonas sediminis
Pathway
tse00230
Purine metabolism
tse01100
Metabolic pathways
tse01110
Biosynthesis of secondary metabolites
Module
tse_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tse00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THMIRHAS_10580 (purL)
Enzymes [BR:
tse01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THMIRHAS_10580 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
BBP45685
UniProt:
A0A6F8PU86
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Position
1174849..1178718
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AA seq
1289 aa
AA seq
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MQIIWGNPAHSAYRLNQLLSKLQTVAAIDAVHSQFVYFVESKIALTADETARLNVLLNKD
AADKVGELSADSCIVTPRIGTISPWSSKATDITHTCGMSSVTRIERGIVYHFFGVEAQDK
PVLEAQVHDRMMEAVHHDFAALDNLFSHQSPKPMKTVDILSGGRDALIVANKEMGLALSL
DEIDYLVEAFNTLQRNPVDAELMMFAQANSEHCRHKIFNADWTIDGVDKPKSLFGMIRNT
YQCNSEGVLSAYSDNAAVIEGPMATRFFPNPASRQYAFSEEPVHFQIKVETHNHPTAISP
WPGAATGSGGEIRDEGATGRGSKPKSGLTGFTVSNLHIPDFVQPWEKAYGKPGRIVTPLD
IMLEGPLGAAAFNNEFGRPAINGYFRTYENALMTHDGEEVRGYHKPIMLAGGLGSIREMH
IKKGDIPVGAKLVILGGPAMLIGLGGGAASSVETGSGSEMLDFASVQRENPEMERRAQEV
IDRCTYLGDDSPIASIHDVGAGGISNAFPELVNDAGKGGVIDLRSVPNDEPGMSPMEIWS
NESQERYVIAVYADKIDQFVEICKRERAIYAIVGEATKEQQLVVKDTVFDNNPVDMPLNV
LLGKPPKMHRTAETRQLPQAGFETANLDLNDVAERLMKLPTIASKNFLITIGDRSITGMV
TRDQMVGPWQVPVANAGITASGYTGYTGEAMASGERPPVALIHPKASARLAIAEAITNIA
CAKIAKMSDIKISANWMAAAGHPGEDSALYDAVETVGMELCPALGIAVPVGKDSMSMKTV
WEENGEAKAVISPMSLNITTFAPVTDVRKTATPQLRTDLGDTELLVIDLGRGQNRIGASC
LAQVYGQVGENSADLDSADDLLNLFNATQSLLADDKIVAYHDRADGGLFVTLAEMAFAGH
TGIKVDISALGNEPVAALCAEEVGVVLQIKAADKAAVEAVLAAHHLTDMAHFIGTLSSDG
VITIINNGSEIFAMPRKQLQKWWSETSFRMQAIRDNEYCAQQEFAAIDNDANTEINPVVT
FDVNEDITAEFTDQPRPKVAILREQGVNGQQEMAAAFTKAGFDAIDVHMSDILSGDVNFA
DFRGLVACGGFSYGDVLGAGRGWANSILFNDTARATFENFFKREDTFSLGVCNGCQMLSN
LKEIIPGAQSWPAFVRNTSEQFEARFSQVQIEKSPSILLQGMEGTRIPVAVAHGEGRMDF
VDGDASQVAGLVGLRYVDAQGNPTEAYPFNPNGSAQGMTGLTTPDGRVTIMMPHPERVFR
TVQNSWHPDDWAEDAPWMRLFRNARKWVG
NT seq
3870 nt
NT seq
+upstream
nt +downstream
nt
atgcaaattatttggggaaatcccgcgcattctgcgtaccgtttaaatcagctgttatct
aagttgcaaaccgtcgccgcgattgatgcggtacattcgcaatttgtctattttgttgag
tcgaagattgcgctgaccgccgatgagacggcacgtttaaacgttttgctgaataaagat
gccgctgataaagtcggtgaattgtcggcggatagctgtattgttacgccacgtattggc
acgatttccccatggtcatctaaagcgaccgacattacccacacttgcgggatgagttcg
gtcacgcgcattgagcgcgggattgtctatcatttctttggtgtggaagcccaagataaa
ccggttttagaagcccaagtgcatgaccgcatgatggaggcggttcatcatgattttgcg
gcgcttgataatctattctcgcatcagtcgccaaaaccgatgaagacggtggatatcctc
tctggcggacgtgatgcgctaattgtcgccaataaagagatgggcttggcattaagtctg
gatgagattgattatctggtagaggcttttaacactttgcagcgtaatcctgttgacgct
gaattaatgatgtttgcgcaagcaaactctgagcactgtcgccataaaatctttaatgcc
gactggacgattgatggcgtagataagccaaaatcgttgtttggtatgattcgtaacacc
tatcaatgtaattctgaaggggtcttgtcggcttacagtgataatgctgcggtcattgaa
gggcctatggcaacacgtttcttcccgaatccggcaagtcgtcaatatgcgttttctgaa
gagcctgtgcatttccaaattaaagttgaaacgcataaccatccgactgcgatttcacct
tggccgggcgctgcgacgggttcgggtggtgaaattcgtgatgaaggtgcaacagggcgc
ggctctaaacctaaatccggtttgactggttttacggtgtctaacttgcacattcctgat
tttgttcagccttgggaaaaagcctacggaaaacctgggcgtatcgtcacgccattggac
attatgctagaaggtcctctaggggcggctgcatttaacaatgagtttggtcgtccggca
attaacggctatttccgtacttatgaaaacgcattgatgacccatgatggtgaagaagtg
cgtggttatcacaagccgattatgttggctggcggtctgggtagcatccgtgaaatgcac
atcaaaaaaggcgatattccggtcggtgctaagttggttatcttgggtggcccagccatg
ctgattggtttaggtggtggtgctgcttcatcggtcgaaaccggttccggttctgagatg
ttggactttgcctctgtgcagcgtgaaaacccagaaatggagcgtcgtgcgcaagaagtc
atcgaccgttgtacctatttgggcgatgattcgcctatcgcttcgattcatgatgttggt
gcgggcggtatctctaacgctttccctgaattggttaacgatgctggtaagggtggggtg
attgatttacgttcggttccgaatgatgagccgggaatgtctccgatggagatctggtca
aatgaatcacaagagcgttatgtgattgcggtttatgcggacaaaattgatcaatttgtc
gaaatttgtaaacgtgaacgtgcgatttatgcgattgttggtgaagcgaccaaagagcag
cagttggtggttaaggataccgtatttgataataatccggtcgatatgccactgaatgtg
ttgttgggtaagccgccgaagatgcatcgtactgccgaaacgcgccaattgccgcaggct
ggttttgaaacggcgaatttggacttaaacgatgttgctgagcgtctgatgaaactgccg
acgatcgcatcgaagaatttcttaattaccatcggtgatcgcagtattaccggtatggtg
acgcgtgatcaaatggttggcccttggcaggttccagttgccaatgcagggattaccgca
tctggttatacgggttataccggtgaagccatggcatctggagagcgtccaccggttgca
ttgattcatccgaaagcttctgcgcgtttggcgatagcggaagcaattaccaatattgcc
tgtgccaaaattgccaagatgtcggacattaaaatttctgccaactggatggccgcagca
ggacatccaggggaagattcggcactgtatgacgctgttgaaacggtgggtatggagttg
tgtccggcattgggtattgctgttccagttggtaaagattcgatgtcgatgaaaactgta
tgggaagagaacggtgaagccaaagcggttatttcgccgatgtcacttaatattacgact
tttgcgccggtcaccgatgtgcgtaaaacggccacgccgcaactgcgtaccgatttgggc
gacactgagcttttagtaatcgatttagggcgcggtcaaaaccgtattggtgcgagttgt
ttggcgcaggtgtatggtcaggttggagaaaattcagcggatttggattcagccgatgat
ttgttgaatcttttcaacgccactcagtcattgctggctgatgacaagattgtcgcttat
cacgatcgcgccgatggtggtttatttgtcactttagcggaaatggcgtttgctggccat
acgggtatcaaagtggatatttctgcattgggcaatgaaccggtcgctgctttatgtgct
gaagaagtcggcgttgttttgcaaatcaaagcagctgataaggcggcagtagaggccgtt
ttggcggcgcatcatttaacggatatggcgcactttatcgggaccttatccagcgatggc
gtgattacgattatcaacaacggatcagagatttttgcgatgccacgtaagcagttgcaa
aaatggtggtcagagacctctttccgaatgcaagccattcgtgataacgaatattgtgcg
caacaggaatttgcggcaattgataatgatgccaataccgaaattaatccagtggttacc
tttgatgtaaatgaggacattactgctgagtttacggatcaaccgcgtccaaaagtcgcc
attttgcgcgaacaaggggtaaacggtcagcaagagatggcggcggcctttactaaagcc
ggttttgatgcgattgatgtgcatatgagcgatatcttgtctggtgatgtgaattttgcc
gacttccgaggtctggtcgcttgtggcggtttctcatacggtgacgtattgggtgccggt
cgcggttgggcgaactcaatcctatttaatgacacagcacgtgcaactttcgagaacttc
tttaaacgtgaagataccttctcgctcggtgtttgtaatggttgtcagatgctgtcaaac
ctaaaagagattattccgggtgcacaaagctggccagcatttgttcgtaatacgtctgag
caatttgaagcgcgtttctcgcaagtgcaaattgaaaagtcgccatctattttattgcaa
ggaatggaaggcacgcgtattccggtagctgtggcgcacggtgaagggcgtatggatttt
gttgacggcgatgcgtcacaagtggctggtcttgtcggactgcgttatgttgatgcacaa
ggcaatccaaccgaggcttatccgtttaatccaaatggctctgcgcaagggatgacggga
ttgaccacgcctgatgggcgagtcacaatcatgatgcctcatcctgagcgtgtgttccgt
acggtgcaaaactcatggcatccggatgattgggccgaagatgccccttggatgcgtttg
ttccgtaatgcccgtaagtgggttggctaa
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