Thermococcus sibiricus: TSIB_0987
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Entry
TSIB_0987 CDS
T00928
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
tsi
Thermococcus sibiricus
Brite
KEGG Orthology (KO) [BR:
tsi00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
tsi03032
]
TSIB_0987
03400 DNA repair and recombination proteins [BR:
tsi03400
]
TSIB_0987
Enzymes [BR:
tsi01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
TSIB_0987
DNA replication proteins [BR:
tsi03032
]
Prokaryotic type
DNA Topoisomerases
TSIB_0987
DNA repair and recombination proteins [BR:
tsi03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
TSIB_0987
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Intein_splicing
Toprim
LAGLIDADG_3
Zn_ribbon_Top1
DUF1272
Motif
Other DBs
NCBI-ProteinID:
ACS90045
UniProt:
C6A350
LinkDB
All DBs
Position
898874..902560
Genome browser
AA seq
1228 aa
AA seq
DB search
MTTLIIAEKPNVAKKIAYALAERKPIRKTIGKVPYYELTRDGKKIIVAPAVGHLFSLAPK
ERTYGYPVFDIDWVPVYLAEKGKSYTKDYIKALKELAKQADEFVIACDYDTEGEVIGYTA
LKYACGVEPSKAKRMKFSALTKQDLLRAWYNLEPTINFGMADAGITRHILDWYWGVNLSR
ALSSAIRKSSGKWHVLSTGRVQGPTLKFLVDREKEIENFVPTPYWVIKMILEKNGEQYTA
NYEKDRILNEEEAKRIVEEAKKGPAFVEKIEITQQKRSPPYPFDLGTLQRESYSAFGYSP
KKTLEIAQKLYEKGYCLHPDSLIPTPKGVKKIEELPKEGEVFALDFDLKLSRARYRLLER
DADELMYKVTLSDRTELYLTGDHPVLAYRDDRLIFVPAEELKDDDQVVLLINPWKFQSAS
ETPKLFDFILKNASSMKDYILYDQSFGSVIRNRIKKAGLKVEILWKFKIKEPTYYKYLRG
KMPVPVFKFLIERGVISKEEAREVFKGFSYSTSLSAVSFEFNEDFWYLYGFVVGDCHLDK
RGQITIGARDRTEETIMAIQEVANSIGVRFAYDSRYKIIRLGSKSLVRLFELLGCPYGNK
MKIFEIPGEVMAKPGWMASFLAGYYDADSHIGTKSTGGRKSLSPQIVLTSKNRRAIYTVK
LMWQLLGVGTYLWERKDKNGNLMAYELKVYSRDSLKFYEIMKDHLRVKRCDLEKVRNAAI
RKRKSYSHHYSVLKVTDWNGKLKSNKKLWKEFDISNQTAHGRGISLDKLRRIRDYLTDED
LRRIATGDVYILGIKSIEKFHYCGKVYDLVVEDYHNFIANGVVVHNCSYPRTSSQKLPKN
LNFRSIIQNLAKIPEYKPHAHELLGKGILKPVEGKKDDPAHPAIYPTGEVPKPGDLNKDE
QNLYDLIVRRFLAAFAEPAIRESMKIIINSNKHHFILNGSRTIKEGWLKIYGKYVKFDEV
ILPKFEKGEKVNVIQIKKEKKKTKPPARYSPASIIKKMEDLGIGTKATRAQILETLYSRG
YIEGKKKIKVTPLGIKVIEALENNVPDIISVELTREFEQKMEEIMARKLKKERVIEESKT
ALIKVLKEFKNKEGEIGKKLLETFLENEKNKKSKRKNVKELKPEEEKVIQVEADFENKGK
EKIIVGSCPKCGGDLVVRYNRRTGKRFVGCSNWPNCNVTYPLLQRGQIIPTGKTCSECGN
APIIKIKERNREYEVCLDMNCNKNRKKK
NT seq
3687 nt
NT seq
+upstream
nt +downstream
nt
atgactacactaataatcgcagagaaacccaatgttgccaagaaaattgcatatgcactt
gctgaacggaaaccaattcgaaaaacaattggaaaagtgccctattatgagcttactcga
gacgggaagaaaataatagttgctcctgcagtgggccatcttttttctctcgctccaaaa
gagagaacttatggatatcctgtctttgatattgattgggtaccagtttatttagcagag
aaagggaaaagctatacaaaggattacataaaagccctcaaagaactagccaaacaagca
gatgagtttgtgattgcatgtgattatgatacagagggtgaagtgatcggttacaccgca
ttaaagtatgcgtgtggggttgaaccctcaaaagcaaaaaggatgaagttttctgctcta
accaaacaagaccttctaagagcttggtataatctcgagcccacaataaacttcggaatg
gctgatgcagggataactagacatattttagattggtactggggtgtaaacctgtcaagg
gccttaagttctgctatacggaagagcagtgggaaatggcatgttctctctaccggtaga
gtccagggccctactctcaaatttttagtggatagagaaaaggaaatcgaaaactttgtc
cccactccttactgggtcataaaaatgattctcgaaaaaaatggggaacaatatactgca
aattatgaaaaagatcgtattctaaacgaagaagaagccaaaagaattgttgaagaggct
aaaaaaggccctgcctttgtagagaaaattgagattactcaacaaaagagaagccctcca
tatccatttgacctagggacccttcaaagagagtcctattccgcctttggttatagcccc
aaaaaaacattagagatagcacagaagctctatgagaaaggttactgccttcacccagat
tcgctcataccaactcccaagggagtgaaaaaaatcgaagagctacccaaggaaggtgaa
gtcttcgcccttgactttgacctcaagttgtcaagggcacgatacaggctactcgaaagg
gatgcagacgagctcatgtataaggttacccttagcgatagaactgagctttatctaaca
ggggatcatccagttctggcttatcgggatgacaggctaatattcgtgcccgctgaggaa
ctcaaagatgatgaccaggtagtgcttctcataaacccttggaagttccagagtgcgagc
gaaactccaaagctgtttgattttatcctcaaaaacgcctcctccatgaaggattacatt
ctctatgatcaatcatttggttccgttataaggaataggataaagaaagctggattgaaa
gtggaaatcctgtggaagttcaaaattaaggaacctacatattacaaatatctcagaggc
aaaatgccagttcctgtatttaagttccttatagagagaggggtaatctcaaaggaagaa
gcgagagaagtttttaaaggattctcatacagtacctcattatctgcggtttcgtttgag
ttcaatgaagacttctggtacttgtatggctttgtagttggggactgccatcttgataaa
aggggtcagataacaataggcgccagggatagaacagaagaaactataatggctattcag
gaagttgcgaattctataggtgttcgatttgcttatgattcaagatacaagataatacgc
ctcggtagcaagtctctggtgagactgtttgaactccttggctgtccatatggaaacaaa
atgaaaatatttgagattcccggtgaggtaatggcaaaacccggatggatggcttcgttc
ttagctggctactacgatgctgatagtcacattggaaccaagtcaacaggcggtagaaaa
tcactgtctcctcaaatcgttttaacctctaagaacagaagagcaatatacacagttaaa
ctcatgtggcagttgctcggtgttggcacctatctgtgggagagaaaagacaaaaatggg
aatctcatggcctacgagcttaaagtgtattcgcgggattctctcaagttctatgagatt
atgaaggaccacctacgagtgaaaaggtgtgatttggaaaaggttcgaaatgctgcgatc
aggaagagaaaatcttattcccatcactacagtgtgctgaaggttacagactggaatggc
aagctaaagagcaataaaaagctttggaaagagtttgacatttccaaccaaacagctcac
gggagggggataagtctcgacaagctcagaaggatcagagattacctgaccgatgaagac
ctccgcaggattgccacgggggacgtttacattcttgggataaagtccatcgagaagttt
cactattgtggtaaggtctacgaccttgtcgttgaggattatcataacttcatcgccaat
ggtgtcgtcgttcacaactgttcctatccgaggacaagctctcaaaagctcccaaagaac
ctaaacttccgctctataatccaaaacctggcaaaaattccagagtataaacctcacgct
catgagctcttaggaaaaggaattttaaaaccagttgaaggcaagaaagatgaccctgcc
catccagccatatacccaacaggtgaagtaccaaagccaggagacttaaacaaagacgaa
caaaatctctatgatttgattgttagacgatttcttgcagcatttgcagaaccagcgatt
agagagagtatgaagattattataaattcaaacaagcatcatttcattcttaacggctca
agaacaattaaagagggatggcttaagatttatggaaaatatgtaaagtttgatgaagtt
attctcccaaaatttgagaaaggagaaaaagtgaatgtcattcagataaaaaaagagaaa
aagaaaaccaaacctcctgcaaggtattctcctgctagcattattaaaaaaatggaagac
ttgggaatcggaacaaaagcaacaagagctcagattctggaaactctttactccagagga
tacatagaggggaaaaagaaaataaaagtcactcctcttggtataaaagtcattgaggcc
ctagaaaataatgtcccagatatcataagtgttgaacttacaagggaatttgaacaaaaa
atggaagagattatggcaagaaaactaaaaaaagagagggtaattgaagaatcaaaaaca
gccctaatcaaagtactaaaagagttcaaaaacaaagaaggtgagatcggaaagaaactc
cttgaaactttcctcgaaaatgagaaaaacaagaagagcaaaagaaagaatgtaaaagaa
ctaaagccagaggaagaaaaagtcatacaagtggaagcggattttgagaacaaaggaaaa
gagaagataatagtggggagctgtcccaagtgtggaggggatctggttgttagatataac
aggagaactggaaaaaggtttgtaggctgttctaattggccaaattgtaatgtgacatac
cccttacttcaaagggggcagataataccaactggaaaaacttgttcagaatgtggaaat
gcaccaataataaaaatcaaggaacgtaatagggaatatgaagtctgtcttgatatgaac
tgcaacaaaaataggaaaaagaaatga
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