Candidatus Thiothrix sulfatifontis: L3K52_08355
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Entry
L3K52_08355 CDS
T09924
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tsj
Candidatus Thiothrix sulfatifontis
Pathway
tsj00790
Folate biosynthesis
tsj01100
Metabolic pathways
tsj01240
Biosynthesis of cofactors
Module
tsj_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
tsj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
L3K52_08355 (folC)
Enzymes [BR:
tsj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
L3K52_08355 (folC)
6.3.2.17 tetrahydrofolate synthase
L3K52_08355 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UOG93723
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Position
1602112..1603329
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AA seq
405 aa
AA seq
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MKTKTLDDWLRWQETQFLTEIKLGLERIRCVAERMGLLHLPVPVLTVGGTNGKGSTCAML
TRILSLQGYSVGTYTSPHLLRYNERIALNGVPVRNADICAAFAAIDLARDDIDLTYFEFG
TLAAVWCFLRAKVDVMVLEVGLGGRLDACNLWDADVAMITSIGIDHVEWLGDNREAIGYE
KSGIMRAGKPVICGDPQPPASIASEAARIGAQLWQYGRDFSADNVPQPALVGEVQRQNAA
VVVTALQQLAEKLPVTPAVIAEGLASVRLMGRMQRILAAPEVILDVAHNPHAATQLAAWL
KKNPVNGKTFAIFSILADKDIVGVLEIMAAQVDEWHVVALSSKRAPRHHELLALMRATGI
RQPIHGHSDFERAWHVIGLKAKKQDRVVAFGSFLVVSAMLEIDIR
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
ttgaagacaaaaacactcgatgattggctgcgttggcaggaaacgcaatttctgaccgaa
atcaagctggggctggaacgaattcgttgcgtggctgagcgcatgggcttgctgcacttg
cccgtgccggtgttgacagtgggcggtacgaatggcaaaggctctacttgcgcgatgctg
acccggattttgtcactgcaaggttatagcgttggcacttacacttccccgcatttgttg
cgttataatgaacgcattgcattgaatggcgtgccggtgcgcaatgcggatatttgtgcc
gcgttcgccgcgattgatctggcgcgtgatgacattgatttgacttactttgaatttggg
acgttggcggcggtgtggtgttttttgcgagccaaggtcgatgtcatggtattggaagtc
ggcttaggcgggcgtttggatgcgtgcaatctgtgggacgcggatgtcgcgatgattacc
agtatcggcattgatcatgtggaatggctgggcgacaaccgtgaagccatcggttatgaa
aaatccgggattatgcgagcaggcaagccagtaatctgcggcgacccgcaacctcccgcc
agcattgccagcgaagccgcccgcatcggagcgcagttgtggcaatacgggcgggatttt
agcgcagataatgtgccgcaacccgcgttagtgggcgaggtgcaacgccaaaatgccgcc
gttgtggtcactgctttgcaacaattggcagaaaaactacccgttacccccgccgttatt
gccgaaggcttagccagcgtgcgcctcatggggcggatgcagcgcatattagccgcgcca
gaagtcatccttgatgtggcgcacaacccccatgccgccacgcaattggcagcatggctg
aaaaaaaatccagtaaacggcaaaacattcgcaattttttctatacttgcagataaggat
attgtcggcgtgttggaaatcatggcagcgcaagtggatgagtggcatgtggtggccttg
tcgagcaaacgcgccccgcgtcatcacgaactgttagcgctgatgcgagccactggtatc
cgccagcctattcacgggcactctgatttcgagcgtgcgtggcatgtgataggtttaaag
gcaaaaaaacaggacagagtggtggcattcggctcttttctggtagtatccgccatgctg
gaaatagatattcgttaa
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