Tsukamurella tyrosinosolvens: ASU32_03425
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Entry
ASU32_03425 CDS
T05267
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
tsm
Tsukamurella tyrosinosolvens
Pathway
tsm00860
Porphyrin metabolism
tsm01100
Metabolic pathways
tsm01110
Biosynthesis of secondary metabolites
tsm01120
Microbial metabolism in diverse environments
tsm01240
Biosynthesis of cofactors
Module
tsm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
tsm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tsm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ASU32_03425
Enzymes [BR:
tsm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
ASU32_03425
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
ASU32_03425
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AUN42806
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Position
719824..721482
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AA seq
552 aa
AA seq
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MSARVAAKTNKPARGRAVAPGRITFVGSGPGDPGLLTLRAEQTIAGARTVYTDPDVPQTV
VDMVGTALPAEPVEADEDAADGTAAKGRKGEPAVRNPATVAPALGEPAEVAKTLLAQARH
GLDVVRLVAGDPLSSDAVLAEVNAVARTQIAFEIVPGLAPATAVPTYAGMALGSAHTEAD
VRGEVDWAALAAAPSPLVLSATAEHLADTASALVENGLAPQTPVAVTAQGSTCKQKTVEA
TLATLNEAGAGLPGPLVVTVGKVVGQRNKLSWWESRALYGWTVLVPRTKDQAAEMSNRLR
AHGSIPMEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFIEFGLDA
RAFSGVKIACVGEQTAAKVRAFGIEPELLPTGEQSSLGMLEVFPPFDDVFDPVNRVLLPR
ADIATETLAEGLRDRGWEIDDVTAYRTVRAAPPPASTREMIKSGDFDAVCFTSSSTVRNL
VGIAGKPHARTIVACIGPKTAETAIEFGLRVDVQPETASVEDLVEALAAHASRLRAEGAL
PPPRKKPRRSRS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
gtgtccgcgcgcgtcgccgcgaagacgaacaagcccgcccggggccgggcggtggcaccg
ggccgcatcaccttcgtgggatccggcccgggagatccggggctcctcaccctgcgcgca
gagcagactatcgcgggcgcccggacggtctacaccgaccccgacgttccgcagaccgtc
gtcgacatggtgggcaccgcgctgccggccgagcccgtcgaggccgacgaggacgccgcc
gacggcaccgccgccaagggccgcaagggcgagcccgccgtgcgcaaccccgccaccgtc
gcgcccgcgctcggcgagcccgccgaggtcgccaagaccctgctggcgcaggcccgccac
ggcctcgacgtcgtgcgcctcgtcgccggtgacccgctgtcgtccgacgcggtgctggcc
gaggtcaacgccgtcgcccgcacgcagatcgccttcgagatcgttccgggcctggcgccc
gcgacggccgtccccacctacgccggcatggcgctggggtcggcgcacaccgaggccgac
gtgcgcggcgaggtcgactgggcggcgctggccgcggccccgtcgcccctggtcctgagc
gcgacggccgagcacctcgccgacaccgcctccgcgctggtcgagaacggcctcgcgccg
cagaccccggtggccgtcaccgcgcagggctcgacctgcaagcagaagaccgtcgaggcc
accctggccacgctgaacgaggccggcgcgggcctgcccggcccgctcgtggtcaccgtc
ggcaaggtcgtgggccagcggaacaagctctcctggtgggagtcgcgcgcgctgtacggc
tggaccgtgctcgtgccccgcaccaaggaccaggccgccgagatgtcgaaccggctgcgc
gcccacgggtccatcccgatggaggtgccgaccatcgctgtcgagccgccccgcagcccc
gcgcagatggagcgcgcggtcaagggcctcgtcgacggtcggtaccagtgggtggtcttc
acctccacgaacgccgtgcgcgccgtgtgggagaagttcatcgagttcggcctggatgcc
cgcgccttctccggcgtgaagatcgcctgcgtcggcgagcagaccgccgccaaggtccgc
gccttcggcatcgagccggagctgctgcccacgggcgagcagtccagcctgggcatgctc
gaggtcttcccgcccttcgacgacgtcttcgacccggtcaaccgcgtcctgctgccgcgc
gccgacatcgccaccgagaccctcgccgagggcctgcgcgaccgcggctgggagatcgac
gacgtgaccgcgtaccgcacggtgcgcgccgcgccgccgcccgcctcgacccgcgagatg
atcaagtccggcgacttcgacgcggtctgcttcacctccagctcgacggtgcgcaacctg
gtcggcatcgccggcaagccgcacgcccgcaccatcgtcgcgtgcatcggcccgaagacg
gccgagaccgcgatcgagttcggcctgcgggtggacgtgcagccggagaccgcgtcggtg
gaggacctcgtcgaggccctcgcggcgcacgcctcccggctccgcgcggagggcgccctg
cccccgccgcggaagaagccgcgccgctcgcgctcgtag
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