Thamnophis sirtalis (common garter snake): 106542268
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Entry
106542268 CDS
T06107
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
tsr
Thamnophis sirtalis (common garter snake)
Pathway
tsr04217
Necroptosis
tsr04620
Toll-like receptor signaling pathway
tsr04621
NOD-like receptor signaling pathway
tsr05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
tsr00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
106542268 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
106542268 (TYK2)
04621 NOD-like receptor signaling pathway
106542268 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
106542268 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tsr01001
]
106542268 (TYK2)
Enzymes [BR:
tsr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
106542268 (TYK2)
Protein kinases [BR:
tsr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
106542268 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
106542268
NCBI-ProteinID:
XP_013913415
UniProt:
A0A6I9XH30
LinkDB
All DBs
Position
Unknown
AA seq
1194 aa
AA seq
DB search
MMPLCHSAIKHSDSVTERCYFAPAGGLRVFLHWKGEAEEQYQTYTKGTPCAEEICSDIAQ
KIGITPTCFSLFALYDPETKRWFPPNYVFDVDSDIKITLHFRMRYYFRNWHGTNDKEPAI
FRSIPRSADSEDRSYRSEQGSAILDKSSFAYLFEQGKYDFINDVASLKDLHTEQEIHQFK
NESLGMAVLHLCHLALKKGISVEEVAEKTSFKECIPRSFCQQIQQNNSLTKFRMKNVFKK
FLQQFQQYTLSTGKLTEQDLMHKYLANLENLAPRFGTELFAAVSLETVSEGEKVPLYING
GHAHLENSYSSSSHGSRPVTHEVLVTGINGIQWRPIPPERPQSQPHKIYFGRKVKTKEHK
SKQSYQPVEQCEAKWAHFCDFQEITHIVVKDCNISIHRQDNKCLDLTLSSHEAALSLISL
VDGYFRLTADSSHYLCHEVAPPQLVMSIQNGIHGPMQEEFILAKLKREGQEDGLYALRWS
VLDFNRLILSVLKNGQVRDGRMSTSTQGNANCGQFRIQRKGNSFVLEGWEQEFPSVQELM
NALKGCTIKSGTDIFSLKRCCLPKPGEISDLIITRKVKDSTRQILNLTQLSFHQIRKNEI
TQRAHLGQGTRTNIYDGVLHVCSGINSDDEAEYFSTEQNNNSCEMHVVLKMLDPSHRDIA
LAFFETASLMSQVSHIHLAFVHGVCVWGSENIMVEEFIEHGPLDVFLRNNKGRVTVGWKF
TIATQLASALSYLEDKNLVHGNVCAKNILLARKGLEDGLLPFIKLSDPGVSFTVLSQEER
VDRIPWIAPECIKDVKNLSTAADKWSFGTTLLEICFDADVPLKERTPSEKERFYEKKHHL
PEPSFKELATLISQCLNYAHGERPSFRTILRDLTQLQPHNPLDISSVNPAFPVSDPTVFQ
KRYLKKIRDLGEGHFGKVSLYCYDPANDGTGEMVAVKSLKSGCSQQLLTSWKKEIEILKT
LYHENIVKYKGCCNEQGEKIVQLIMEYVPLGSLRDYLPKHNVSLAHILLFAQQICEGMAY
LHSLHYIHRDLAARNVLLENENVVKIGDFGLAKAIPKGHDYYRVCEDGDSPVFWYAVECL
KECKFYYASDVWSFGVTLYELLTWCDSSQSPPQRFIEMIGMTQGQMTVLRLIELLDRGER
LPSPKDCPCEIYHLMKNCWESEASFRPTFTNLAPLLKAFHEKYKTQAPSVFSVC
NT seq
3585 nt
NT seq
+upstream
nt +downstream
nt
atgatgcctctctgccactctgcaataaaacacagtgactcagtcacggagaggtgctat
tttgcacctgctggaggtctgagggtattcttgcactggaagggtgaggcagaggaacag
tatcagacatacaccaaagggactccttgtgctgaagagatctgcagtgatattgcacag
aagataggaatcacaccaacttgcttcagtctgtttgcactctatgacccagagaccaaa
cgttggttccctcccaactatgtctttgatgttgatagtgatatcaagatcactttgcat
tttcgtatgagatattattttcgaaactggcatggaacaaatgacaaggagccagccata
tttcgcagtattcctcgctcagctgactcagaggacagatcatatagaagcgaacaaggc
agtgccatcctggataaatcgtcatttgcctatctctttgagcaagggaaatatgacttc
atcaatgatgttgcctccttaaaagacctgcacactgaacaggaaattcaccaatttaaa
aatgagagcctgggcatggctgtcctccacctgtgtcatcttgccctgaagaaaggcatt
tctgttgaggaggtggcagagaaaacaagtttcaaagagtgcatcccacggtccttttgc
caacagattcagcagaacaattctttgaccaagttccgcatgaagaatgttttcaagaaa
ttcttgcaacagttccagcagtacacattgagcactggtaaactgacagaacaggatctc
atgcacaagtacttagctaacttggaaaacctggctccgcgttttgggactgagctcttt
gcagctgtttcactggaaactgtttcggagggtgagaaggtgccactttatatcaatggt
ggtcatgcgcatctagagaactcctattcttcttcttctcacggtagcaggcctgtcaca
catgaagtcttggtcacaggcattaatgggattcagtggcggcctatccctcctgagaga
ccacagagccagccccataaaatttattttgggaggaaagtcaagactaaggagcacaag
tccaagcagtcctaccaaccagtggagcaatgtgaagctaaatgggcacacttttgtgac
tttcaagagatcacacatattgttgtcaaagattgcaacatcagcatccatcgccaagac
aataagtgtctggatttgactttgtcatcccatgaagctgctctctccttgatttcatta
gtagatggttacttcagattaacagctgattctagccattatctgtgtcatgaagttgcc
ccaccacaactcgttatgagcatccagaatggtattcatggacccatgcaggaagagttc
attctggctaagctgaagcgtgaagggcaggaagatgggctgtatgccctccgttggagt
gtccttgatttcaacagattgattctatcggtactgaagaatggccaagtgagagatggg
agaatgagtaccagtacccaaggcaatgcaaactgtggacagttccggatccagaggaaa
ggaaattcctttgtacttgaaggctgggagcaagagtttcctagtgtccaagaactaatg
aatgctctcaaaggctgtactataaaatctggaacggacatcttcagtttgaagagatgc
tgcctcccaaaaccaggagaaatctcagacttaatcatcacacgaaaagtgaaagacagc
acaaggcagattctgaatttgactcagctgagttttcatcagattcggaagaatgagatt
acacagagagcgcacttgggacaaggaacacgaaccaatatttatgatggtgtacttcat
gtatgcagtgggatcaacagtgatgatgaggcagagtatttttctactgagcagaataac
aatagttgtgagatgcatgtggtactcaagatgttggaccccagtcatagagacattgct
ctggcattctttgaaacagccagcctgatgagccaggtgtcccatatccacttagccttt
gttcacggggtttgtgtatggggttcagagaatataatggtggaagaattcattgagcat
ggtcccctggatgtctttttgcgtaataacaaaggacgggtaacagtaggctggaaattc
actattgcaacacaattagccagtgccctcagttaccttgaagataaaaacctagtgcat
ggcaatgtatgtgccaaaaacatcctgttggcaaggaaaggtttggaagatggcctgctg
ccttttattaagctcagtgacccaggagtcagcttcactgtactttcccaagaagaaagg
gttgacaggatcccgtggattgctccagagtgtatcaaagatgtaaaaaaccttagcaca
gcagctgacaaatggagttttgggaccacattgctggaaatatgttttgatgcagatgtg
ccactaaaagaacgcactccttctgagaaagaacgtttttatgagaagaagcatcatctt
ccagagccatccttcaaagaactagctaccctaatcagccagtgcctaaactatgctcat
ggagagcgaccctctttccggactatcttacgagacctcactcaactgcaaccacataat
cctcttgacattagctctgtgaatcctgcgttccctgtatcagatcctactgtctttcag
aagcgttacctgaaaaagattcgagatctgggtgagggccactttggtaaagtgagcctg
tattgttatgatcctgccaatgatggcactggtgagatggtagcagtgaagtcattgaaa
tcaggttgcagccagcagctcttgactagttggaaaaaggagattgagatcttgaagaca
ctctaccatgagaatattgtaaaatacaaaggctgctgcaacgagcaaggagaaaagatt
gtgcagcttatcatggaatatgtgccactgggaagtctgagggattatctccccaagcac
aatgtcagcttggcccacattctcctctttgcccagcagatttgtgagggaatggcttat
ctccactccttgcactacatccacagagacctagcagctagaaatgtgctcctggagaat
gaaaatgtggtaaagattggagactttggtcttgccaaagccatccccaaaggacatgac
tattatcgtgtctgtgaagatggagacagccccgtcttctggtatgctgtggaatgcctc
aaggaatgtaaattctattatgcttctgatgtctggtcctttggagtgactttatatgaa
ctgttaacatggtgtgattcaagtcagagccctccacaaagatttattgagatgattgga
atgactcagggtcagatgacagtgctgaggctcattgagctgttggacagaggggaaaga
ctgcccagtccaaaagactgcccttgtgagatttatcacctgatgaaaaactgttgggaa
tctgaagcttcattccgcccaaccttcacaaacctagcgcccctcctcaaagccttccat
gaaaagtacaagacccaggccccttcagttttcagcgtgtgttga
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