Thiomicrolovo subterrani: WCX49_04395
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Entry
WCX49_04395 CDS
T11234
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tsub Thiomicrolovo subterrani
Pathway
tsub00300
Lysine biosynthesis
tsub00550
Peptidoglycan biosynthesis
tsub01100
Metabolic pathways
tsub01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tsub00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
WCX49_04395 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WCX49_04395 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
WCX49_04395 (murF)
Enzymes [BR:
tsub01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
WCX49_04395 (murF)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
XAU03697
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Position
868991..870433
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AA seq
480 aa
AA seq
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MTPAALQTLAVVTNLALVLTLGWYLILNLQWYSYKLERVVLNHHKRSWHLFYFVTPFLAY
FVLGEFFPLFFLLYLGAFIWWYVRLDKKLVLTWRVKRFLILLAALALFGDFLCLIKSCGT
LPLFLPLLLAWLLSTGIEKFLFLAYKREAQRKLARLENLTVVAVTGSYGKTSMKNFIAQL
LGTQFEVYMTPRSVNTLGGIIKDINEALPETARVYVCEAGARRPGDILEIAQLVAPHYAV
VGKVGPQHLEYFGDLETIVRTKLELIQSPRLKAAFVHYEATEEPHENVRFFGTEIENIAA
DLEGTAFDLALDGEQLHLHAPVLGGFNAINIEAAVLIARAVGMDDAAITRGVEALKPVEH
RLQRIDAGGKIILDDGYNGNIDGMKEGIRLCALHSGRKVIVTPGLVESTEALNRELIEAI
NGVFDLVIVTGKLNAAQFKAQLKIADALYLEEKSTLTAVLAEKTRPGDIIYFANDAPNFI
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgaccccggcggctctgcagacactggcggtcgtgaccaacctcgcgctggtgctgacg
ctgggatggtatctcatcctcaacctgcagtggtacagctacaagctcgagcgcgtcgtg
ctcaaccaccacaaacgcagctggcaccttttttacttcgtcaccccttttctcgcctat
ttcgttctgggcgaatttttcccgctctttttcctcctctatctgggggcctttatctgg
tggtacgtgcgcctggacaagaagctggttctgacctggcgggtcaaacgtttcctcatc
ctgctcgctgcgctggcgctgttcggcgatttcctctgccttatcaagagctgcggtacg
ctcccccttttcctcccgcttctgctcgcgtggctgctttcgacggggatagaaaagttt
ctcttcctcgcctataagcgggaggcgcagcgcaaactggcccggctggaaaacctgacg
gttgtcgccgtgacggggagctacggcaaaacgagcatgaagaacttcatcgcccagctg
ctcgggacgcagttcgaggtttacatgacgccgcgcagcgtcaataccctcggcgggatc
atcaaagatatcaacgaagcccttcccgaaacggcccgggtatacgtctgcgaagcgggc
gcgcgccgtcccggggatatcctcgagatcgcgcagctggtcgcaccgcactatgccgtc
gtcggcaaggtcggcccgcagcacctggagtatttcggcgacctggagacgatcgtgcgc
accaagctggagctgatccagtcgccgcgtctgaaagcggcgttcgtccactatgaagcg
acggaagaaccgcatgaaaacgtccgtttcttcggaacggagatcgaaaacatcgccgcc
gacctggaggggacggcgttcgacctcgcccttgacggggagcagttgcatctgcacgcc
ccggtgctcgggggcttcaacgccatcaatatcgaggccgccgtgctgatcgcccgggcg
gtggggatggatgatgccgccatcacccgcggggtggaagccctgaaaccggtcgaacac
cgcctgcagcgcatcgatgccggcggaaagatcatccttgacgacggctataacggcaat
atcgacgggatgaaagaggggatccgcctctgtgctttgcactccgggcgcaaggtgatc
gtcacccctggcctcgtggagagcacggaagccctcaaccgcgaactgatcgaagcgatc
aacggggtgttcgacctcgtgatcgtcaccgggaagctcaatgcggcgcagttcaaggcg
cagctgaagatcgccgacgctctctaccttgaagagaagagtaccctgaccgccgtcctg
gccgaaaagacccgtccaggcgatatcatctacttcgccaacgacgccccgaactttatc
tag
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