Thiobacillus sedimenti: VA613_00710
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Entry
VA613_00710 CDS
T10461
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tsw Thiobacillus sedimenti
Pathway
tsw00300
Lysine biosynthesis
tsw00550
Peptidoglycan biosynthesis
tsw01100
Metabolic pathways
tsw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tsw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
VA613_00710 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
VA613_00710 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
VA613_00710 (murF)
Enzymes [BR:
tsw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
VA613_00710 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WRS39419
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Position
150190..151581
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AA seq
463 aa
AA seq
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MSAQMMRLSEAAAMLGLAHAGGDADVLRVCTDSRSIRPGDLFIALRGEKFDGGTFAADAL
RQGAVGVVLDHAQAPAIAQALRVDDTRLALGQLAAAWRRRFALPIVAITGSNGKTTVKEM
LGAILRAEAGNEAAVLQTEGNLNNDIGLPLMLLRLRESHAFAVLEMGMNHAGEIDYLTRL
ARPDVAVVNNALSAHIGFLGSVENIARAKGEIFNGLSDAGIAVFNADDAHAHLWRDANAR
RSVIDFGLVHPAAVRGQYRPLDFGSALTLVLPGATLDITLQVPGEHNVMNALAAAAAAFA
LDVSHRSIVTGLSGFTGVKGRLQRKPGLHGAIFIDDTYNANPDSVKAALAVLAQQPGKKL
LVLGDMGELGSDAADMHGDIGRAARAARVDRLLALGELTQHTVAAFGAGAMHFERIEELL
AELENDLTPDTTVLVKGSRFMQMERVVRSFTEAAGDVAGAKGH
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcgcagatgatgcgtctttcggaagccgccgcgatgctcggccttgcgcatgcc
gggggcgacgcggacgtgctccgcgtctgcaccgacagccgcagcatccggccgggcgat
ctcttcatcgcgctgcgcggcgaaaaattcgacggcggcacgtttgcggccgacgcgctc
cggcagggcgcggtcggcgtcgtgctcgaccatgcccaggcgcccgccatcgcgcaggca
ctgcgcgtcgacgatacgcggctggcgctggggcagctggccgccgcgtggcgtcgacgc
ttcgcgttgcccatcgtggcgatcaccggcagcaacggcaagacgaccgtcaaggaaatg
ctgggggcgatcctgcgtgccgaagcggggaacgaggccgcggtgctgcagaccgagggc
aacctcaacaacgacatcggcctgccgctgatgctgctgcggctgcgcgagtcgcacgcg
ttcgcggtgctggagatgggcatgaaccacgccggcgagatcgactacctgacgcgcctc
gcgcgccccgacgtcgcggtggtgaacaatgccctgtcggcgcacatcggctttctcgga
tcggtcgagaacatcgcgcgtgccaagggggagatcttcaacggcctgtccgatgccggc
atcgccgtattcaatgccgacgatgcgcacgcgcacctgtggcgggatgcgaatgcacgc
cgcagcgtgatcgacttcggcctcgtgcatcccgccgcggtgcgcgggcaatatcgtccc
ctcgacttcggctccgccctcacgctggtgctccccggtgcgacgctcgacatcacgctg
caggtccccggcgagcacaacgtcatgaacgcgctggccgccgcggcggccgcgttcgcg
ctcgacgtcagccaccgcagcatcgtgacgggactgtccggcttcaccggcgtcaagggt
cgcctgcaacggaaacccgggctgcatggcgcgatcttcatcgacgacacctacaacgcc
aacccggattcggtgaaggccgcgctggcggtgctcgcgcagcagcccggcaagaagctg
ctcgtgctgggcgacatgggggaactgggcagcgacgcggcggacatgcatggcgacatc
gggcgcgccgcacgcgcggcccgggtggaccggctgctcgcgctgggcgagcttacccag
cacaccgtcgcggccttcggtgccggcgccatgcacttcgagcggatcgaggaactgctc
gccgaactcgagaacgacctgacgcccgacacgaccgtgctggtgaagggctcgcgcttc
atgcagatggagcgcgtggtcagaagctttacggaagctgccggcgacgtcgccggagcg
aagggacactga
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