Thiobacillus sedimenti: VA613_10525
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Entry
VA613_10525 CDS
T10461
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tsw Thiobacillus sedimenti
Pathway
tsw00790
Folate biosynthesis
tsw01100
Metabolic pathways
tsw01240
Biosynthesis of cofactors
Module
tsw_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
Enzymes [BR:
tsw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
VA613_10525 (folC)
6.3.2.17 tetrahydrofolate synthase
VA613_10525 (folC)
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NCBI-ProteinID:
WRS38438
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Position
complement(2123482..2124756)
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AA seq
424 aa
AA seq
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MADTPSALDAWLARLEQLHPSTIELGLDRVRRVKDALGLAPAFPLIVVGGTNGKGSTCAY
LEAVLGAAGYRTGLYTSPHLLRYNERVRIAGREADDADLVAAFERIDVARGDTSLTYFEF
GTLGAMLQFIDAGVDVAILEVGLGGRLDAVNVFDADAAIVTSVDLDHIEYLGDTREQIGF
EKAGIYRAGRPAICADPVPPASLLEQAGRIGAGLRCYGREFAARREGGRWRYEGVDATWP
ALPLPAMPGPFQLRNAAAALAALEALAARLPVGEAAIRAGLAEARVAGRFQRVACAPEVI
LDVAHNPEAARALAAALREQPAKGRTLAVVGMLADKDAAGVVAALRDAIDAWWACTPDSP
RARDAATLAAIVRDATGAAEVSVQPDVWRALAEARGAAREDDRILVFGSFYTVAAVLDHA
ATQQ
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
gtggccgataccccatccgctctggacgcctggctggcgcgtctggagcagctgcacccg
agcacgatcgagctgggcctcgaccgcgtgcgccgggtcaaggatgcgctcgggctcgcg
cccgcctttccgctgatcgtcgtcggcggcaccaacggcaaggggtcgacctgcgcctat
ctcgaagcggtgctcggcgcggccggttaccggaccgggctctacacgtcgccgcacttg
ctgcgctacaacgagcgcgtgcggattgcggggcgcgaggcggacgacgccgacctggtc
gccgcattcgaacggatcgacgtggcacgcggcgacacgtcgctgacgtatttcgagttc
ggtacgctgggcgccatgctgcagttcatcgatgctggcgtcgacgtcgcgatcctcgag
gtcggactcggcggccgccttgacgcggtgaacgtcttcgacgccgacgccgcgatcgtg
accagcgtcgacctcgaccacatcgaatacctcggcgatacccgcgagcaaatcggtttc
gagaaggccggcatctaccgcgcgggacggcctgccatctgcgccgatccggtgccgccg
gcaagcctgctggaacaggccgggcggatcggcgccggcctgcgctgctacgggcgcgag
ttcgccgcccgccgcgagggcggacgctggcgctacgagggtgtcgacgcgacctggccg
gcgttgccgctgccggccatgcccgggcccttccagctgcgcaacgcggcggccgcgctg
gccgcgctcgaggcgctggccgcgcgcctgccggtcggcgaggcggcgattcgcgcgggg
ctggcggaggcgcgcgtcgccggccgctttcagcgcgtcgcgtgcgcaccggaggtgatc
ctcgacgtggcgcacaatccggaggccgcgcgcgcgctcgccgccgccttgcgcgaacag
ccggccaaggggcgcacgctcgccgtcgtcggcatgctggccgacaaggacgccgcaggc
gtggtggcagccctgcgcgacgcgatcgacgcctggtgggcgtgcacgccggattcgcca
cgcgcgcgggacgccgccacgctcgccgcgatcgtgcgcgacgcgaccggcgcggccgaa
gtgagcgtgcagccggatgtgtggcgggcgctcgcggaggcgcggggcgccgcgcgcgaa
gatgatagaattctcgtcttcggttcgttctacaccgttgccgccgtgctcgatcatgcc
gccacccagcagtga
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