Thiobacillus sedimenti: VA613_10585
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Entry
VA613_10585 CDS
T10461
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tsw Thiobacillus sedimenti
Pathway
tsw00290
Valine, leucine and isoleucine biosynthesis
tsw00660
C5-Branched dibasic acid metabolism
tsw01100
Metabolic pathways
tsw01110
Biosynthesis of secondary metabolites
tsw01210
2-Oxocarboxylic acid metabolism
tsw01230
Biosynthesis of amino acids
Module
tsw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
tsw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
VA613_10585 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
VA613_10585 (leuC)
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NCBI-ProteinID:
WRS38449
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Position
complement(2135761..2137164)
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AA seq
467 aa
AA seq
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MPGQTLFQKLWDAHVVHVEPDGTTLLYIDRHLVHEVTSPQAFEGLKLAGRKPRRTDAAIA
VPDHNVPTTDRSQGIADPVSRLQVETLDANCAEFGITEFGMNDVRQGIVHVIGPEEGLTL
PGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLWQKPSKTMLVRVDGVLGRGVT
AKDIALAVIGEIGTAGGTGYAIEFGGSAIRALSMEGRMTLCNMAIEAGARAGMVAVDQTT
IDYVQGRPYAPNGDAWDKAVAWWNTLHSDADAKFDRVVELDAAAIEPEVTWGTSPEMVTT
IGGRVPNPADAPSEVKRHDWTRALEYMGLAAGTPIAEIAVDKVFIGSCTNSRIEDLREAA
AVARGRKVAPNVKLAMVVPGSGLVKRQAEAEGLDRIFVEAGFEWREPGCSMCLAMNADRL
EPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAVTGHFVDVRKL
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgcccggccagaccctgttccagaaattgtgggatgcccacgtcgtccacgtcgaaccc
gacggcaccaccctgctgtacatcgaccgccacctggtgcacgaagtcaccagcccgcag
gcgttcgaggggctgaagctcgccggccgcaagccgcgccgcaccgacgccgcgatcgcg
gtgcccgaccacaacgtgccgacgaccgaccgctcgcagggtatcgccgaccccgtgtcg
cgcctgcaggtcgagacgctcgacgccaactgcgccgaattcggcatcaccgaattcggg
atgaacgacgtccgccagggcatcgtccacgtgatcgggcccgaggaggggctgaccctg
ccgggcatgacggtcgtgtgcggcgactcgcacacctcgacgcacggtgccttcggtgcg
ctggcgttcggcatcggcacctccgaggtcgagcacgtgctggcgacccagtgcctctgg
cagaaaccttcgaagaccatgctggtcagggtcgacggcgtgctggggcgcggcgtgacc
gcgaaggacatcgccctcgcggtcatcggcgagatcggcaccgccggcggaaccggctac
gcgatcgagttcggcggctcggcgatccgggcgctgtcgatggaaggccgcatgacgctg
tgcaacatggcgatcgaggcgggcgcgcgcgccggcatggtcgcggtcgaccagaccacg
atcgactacgtgcagggccgtccctatgcacccaacggcgacgcctgggacaaggccgtg
gcgtggtggaacacgctgcattcggacgccgacgcgaaattcgaccgcgtggtcgaactg
gacgccgccgcgatcgagccggaggtcacctggggcacgtcgcccgagatggtgacgacc
atcggcggccgtgtgcctaatccggccgacgcgccgagcgaggtcaagcgccacgactgg
acgcgtgcgctcgaatacatgggccttgccgccggcacgccgatcgccgagatcgcggtc
gacaaggtcttcatcggctcgtgcaccaattcgcggatcgaggacctgcgcgaagcggcc
gcggtggccaggggccgcaaggtcgcccccaacgtcaagctggcgatggtggtgcccggc
tcgggactggtgaagcggcaggccgaggccgagggcctggaccggatcttcgtcgaggcg
ggtttcgaatggcgcgagccgggctgctcgatgtgcctggcgatgaacgcggaccggctg
gagccgggcgagcgctgtgcgtcgacgtcgaaccgcaacttcgaggggcgccaggggcag
ggcgggcggacccatctggtcagcccggcgatggccgccgcggccgccgtcaccgggcat
ttcgtggacgttcgcaagttgtaa
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