Candidatus Thiodictyon syntrophicum: THSYN_28175
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Entry
THSYN_28175 CDS
T05211
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tsy
Candidatus Thiodictyon syntrophicum
Pathway
tsy00230
Purine metabolism
tsy01100
Metabolic pathways
tsy01110
Biosynthesis of secondary metabolites
Module
tsy_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tsy00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THSYN_28175
Enzymes [BR:
tsy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THSYN_28175
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AUB84434
UniProt:
A0A2K8UFS0
LinkDB
All DBs
Position
complement(6627379..6631281)
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AA seq
1300 aa
AA seq
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MLVLRGAPALSDFRLRKLQGRLAAALGQDVRLTAQFVHLADLERDLDQAEQAVLDRLLRY
GPSLPGQAPVGQLILTVPRAGTISPWSSKATEIARNCGLTMVRRLERGTAWYLDAGAPLA
AADLHRAADLLHDRMTQGVLLDLADAGRLFDHAEPRPLTRVGLRVGGRASLVQANAGLGL
ALSDDEIDYLAASFLALDRDPTDVELMMFAQANSEHCRHKVFNANWTIDGVRQEQTLFQM
IRNTTERAPAGVLSAYRDNAAVMEGWDGRRFLPDPVTGIYGEHEEPIHILMKVETHNHPT
AIAPDPGAATGAGGEIRDEGATGLGAKPKAGLTGFSVSNLRIPGGEQPWERDYGRPGRIC
SALEIMLEGPIGAAAFNNEFGRPNLAGYFRTYEQAIPGPDGAPELRGYHKPIMLAGGIGN
IRAEHVAKRPFPAGTPLVVLGGPAMLIGLGGGAASSMTSGASAADLDFASVQRANPEMER
RCQEVIDRCWARGEANPILFIHDVGAGGLSNALPELVHDGGRGGRFELRRVPSAEPGMTP
LEIWCNEAQERYVLAIAAAELASFQAICERERCPYAVVGEALEPAHLSMTDARLGEDPID
LPLQLLFGKPPRMHREAARLNPPRTRLDLKAIRLDEAIARVLALPTVADKSFLITIGDRS
ITGLVARDQMVGPWQVPVADCAVTASDYRGFTGEAMALGERTPLALLDAPAAGRMAVGEA
LTNIAAAAITGLPEVRLSANWMAAVGHPGEDARLYDAVRAVGLELCPALGIAIPVGKDSM
SMKTVWADPDGAPLAMTAPLSLIVSAFAPVTDVRATLTPQLRTDRGDTDLILIDLGQGKN
RLGGSCLAQVYGQLGDPAVDGVPDLDDPELLKRFFGAIQELNAEGLLLAYHDRSDGGLLA
TLCEMAFAGRCGVDLDLAPVGPGDLAALFSEELGAVIQVCHADTDEVLLILAQHGLEDLS
PVIGTLDEGEAIRLRRHSEVLYCGSRAGLQSIWSETSFRMQGLRDHPDCAAEAYERIESE
APGLSARLVFDPEDDLAFPFLARGVRPPIAILRDQGVNGQLEMAAAFHAAGFECVDVHLS
DIIAGRVDLARFRGLAACGGFSYGDVLGAGEGWAKTILYNPRARDQFQAFFERSDTFTLG
VCNGCQMLSNLHELIPGTGHWPRFVRNRSEQFEARTLLVEVLPTPSILLAGMAGSRMPIA
VAHGEGRAEFRDGEHLAAARGGVAVRYLEHDGRIAHAYPANPNGSPDGIAGLTSLDGRVT
IMMPHPERVFRTVQHSWHPDDWGPDGPWMRLFRNARVWVG
NT seq
3903 nt
NT seq
+upstream
nt +downstream
nt
atgctcgtccttcgcggggccccagcgctgtccgatttccgtctccgcaagcttcagggg
cgccttgccgcggccctcgggcaagacgtgaggctcactgcccagttcgtccacctggcc
gatctggagcgggacctggaccaggccgaacaggccgtcctcgaccgcctgctgcgctac
ggccccagcctgcccggccaggcgccggtcggccagttgatcctgacggtgccgcgcgcc
gggaccatctcgccctggtcctccaaggcgaccgagattgcccgcaattgcggcctgacc
atggtgcgtcgcctggagcggggcaccgcctggtatctggatgccggcgcccccctggcc
gcggcggacctgcaccgggcggcggacctgctgcacgatcgcatgacccagggcgtcctg
ttggacctcgcggacgcgggtcggctcttcgaccatgccgagccccggccgctcacccgg
gtggggctgcgtgtcggcggccgggcctcactggtgcaggccaacgccgggctgggactg
gccctgtccgatgatgagatcgactacctggccgcgagcttcctggcgctggaccgggac
ccgaccgacgtggagctgatgatgttcgcccaggcgaactcggagcactgtcggcacaag
gtcttcaacgccaactggaccatcgacggggtgcggcaggagcagacactgttccagatg
atccgcaacaccaccgagcgcgccccggccggggtcctctccgcctaccgggacaatgcc
gcggtgatggagggctgggacgggcggcgcttcctgccggacccggtgaccggcatctat
ggggaacacgaggagcccatccatatcctgatgaaggtggagacccataaccaccccacg
gccatcgccccggacccgggggcggcgaccggtgcgggcggggagatccgcgacgagggg
gcgaccgggctcggggccaagcccaaggcgggcctcaccgggttctcggtctccaacctg
cgcatccccggcggcgagcagccctgggagcgggattatggacggcccgggcgcatctgc
tccgcactggagatcatgctggagggccccatcggcgccgccgccttcaacaacgagttc
gggcggcccaacctggccggctatttccgtacctatgaacaggccatcccgggcccggac
ggggccccggaactgcgcggctatcacaagccgatcatgctggcgggcggtatcggcaac
atccgcgccgaacacgtcgcgaaaaggcccttcccggcgggcacaccgctagtggtgctc
ggcggtccggccatgctgatcgggctgggcggcggggcggcctccagcatgacctcgggg
gcatccgccgctgatctcgatttcgcctcggtgcagcgcgccaacccggagatggagcgc
cgctgccaggaggtgatcgaccgttgctgggcgcgcggtgaggccaatccgatcctcttc
atccacgacgtgggcgccggggggctgtccaacgccctgcccgaactggtgcacgacggc
ggccggggcgggcgcttcgagctgcgccgggtgccgagcgccgagccgggcatgacgccc
ctggagatctggtgcaacgaggcccaggagcgctatgtactcgccatcgccgccgcggag
ttggcgagcttccaggcgatctgtgaacgcgagcgctgcccctatgccgtggtcggggag
gcgctcgaaccggcccacctgtccatgacggacgcgcgcctcggggaggacccgatcgac
ctgccgctgcagctcctgttcggcaagccgccgcggatgcatcgcgaggcggcgcgtctg
aacccgccgcgcacgcggctcgatctcaaggccatccgcctggacgaggcaatcgcccgg
gtcctggcgctgccgacggtcgcggacaagtcattcctgatcaccatcggggaccgcagc
atcacgggcctggtggcgcgcgaccagatggttgggccctggcaggtgccggtcgccgac
tgcgcggtcaccgcgagcgactaccgcggcttcaccggcgaggccatggcgctcggggag
cgtaccccgctggcgctgctggacgccccggcggccgggcgcatggccgtgggggaggcg
ctcaccaacatcgcggcggcggccatcaccgggctgcctgaggtccggctctccgccaac
tggatggccgccgtcgggcatccgggtgaggacgcccgactctatgacgcggtgcgcgcc
gtcggcctggaactgtgcccggcgctcggcatcgcgataccggtcggcaaggactccatg
agcatgaagaccgtctgggccgaccccgacggcgcgccgctggccatgaccgcgcccctg
tcgctgatcgtctccgccttcgccccggtgacggacgtgcgcgccaccctgacgccgcag
ttgcgcaccgatcggggggacacggacctgatcctgatcgacctggggcaggggaagaac
cgcctgggcggctcctgcctggcccaggtctatgggcagctcggggaccccgccgtcgat
ggggtgccggacctggacgacccggaactgctcaagcgcttcttcggggcgattcaggaa
ctcaacgccgagggactgctgctggcctatcacgatcgttcggacggcggactgctcgcg
accctctgtgagatggccttcgccgggcgctgcggggtggacctggacctggcaccggtg
gggccgggggacctggccgccctgttcagcgaggaactgggcgcggtgatccaggtctgt
catgccgacaccgatgaggtgctcctgatcctcgcccagcacggtctggaggacctgagc
ccggtcatcggcaccctggacgagggcgaggccatccggctgcgccgccacagcgaggtg
ctctattgcggcagccgcgccgggctccagtccatctggtccgagaccagcttccggatg
caggggctgcgcgaccacccggactgtgccgccgaggcctatgagcgcatcgagagcgag
gccccgggtctgagcgcgcgcctggtcttcgacccggaggacgacctcgccttcccgttt
cttgcgcgcggcgtccgtccgcccatcgccatcctgcgcgatcagggcgtcaacggccaa
ctggagatggccgccgccttccacgccgccggcttcgagtgtgtggacgtgcacctctcc
gacatcattgccgggcgggtggatctcgcgcgctttcgcggcctggccgcctgcggcggc
ttttcctacggcgatgtcctgggcgccggcgagggctgggccaagactatcctctataac
ccccgggcgcgcgaccagttccaagccttcttcgagcggtccgacaccttcaccctgggg
gtgtgtaacggctgccagatgctctccaatctccacgagctgatccccggcaccggccac
tggccgcgcttcgtgcgcaaccgctccgagcagttcgaggcgcgcaccctgctggtcgag
gtcctgccgaccccctcgatcctcctggccggcatggccggttcccggatgcccatcgcc
gtcgcccacggcgagggccgggccgagttccgcgacggcgagcacctggccgcggcccgc
ggcggggtggcggtgcgctacctggagcacgacggacgcatcgcccacgcctacccggcc
aaccccaacggctccccggacggcatcgccggcctgaccagcctggacgggcgggtcacc
atcatgatgccccacccggagcgggtcttccgcaccgtccagcactcctggcaccccgat
gattgggggccggatgggccttggatgcggctgtttcggaatgcgcgggtgtgggtgggg
tga
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