KEGG   Pseudothermotoga thermarum: Theth_0462
Entry
Theth_0462        CDS       T01554                                 
Name
(GenBank) IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
tta  Pseudothermotoga thermarum
Pathway
tta00230  Purine metabolism
tta00670  One carbon pool by folate
tta01100  Metabolic pathways
tta01110  Biosynthesis of secondary metabolites
Module
tta_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:tta00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    Theth_0462
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Theth_0462
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tta04147]
    Theth_0462
Enzymes [BR:tta01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     Theth_0462
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     Theth_0462
Exosome [BR:tta04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   Theth_0462
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: AEH50555
UniProt: F7YWW3
LinkDB
Position
456318..457841
AA seq 507 aa
MVKRALISVYDKTSLLDFAKFLFEQNVEIISSGGTARFLKENGIPVKTVEEITGFPEILE
GRVKTLHPKIHGAILADRSKPLHLQQLEQLGIETIDMVVVNLYPFEKMYIANASDEEMIE
NIDIGGPTLIRAAAKNYKNVAIVCDPKDYPIVVDEIKQYGEVRLETRLKLAQKAFELTSY
YDSIVARYFRDKTKEIFPEFLTLGFKLHQTLRYGENPHQMAAAYVDLRYEGTIMDTTQLW
GKELSFNNIADADAALSIVKEFTQPCAVGVKHTNPCGVACGETLLEAFEKMYEADPISIF
GGIVALNRTVDEKTAEKMSQIFLEVVIAPDYDPKALEILMKKKNLRILKVKIDRLNQNEL
DLRKVSGGLLVQTPDSTDYNELRCVTKREPTPQELEDLLFAWKVVKHVKSNAIVLAKNLA
TVGIGAGQVNRLWPTEHCVRIAGPKANGAVLASDAFFPFPDAVEVAAKAGVTAIIQPGGS
IRDEEVIKVANEYNIAMIFTGTRHFKH
NT seq 1524 nt   +upstreamnt  +downstreamnt
gtggtaaagagagctttgatctcagtttacgataaaacaagccttttggattttgccaaa
ttccttttcgagcaaaacgttgagataatcagctccggtggaacggcgaggttcttgaag
gaaaatggtatacctgtgaaaaccgttgaagagataaccggctttccggaaattttggaa
ggaagggttaaaacacttcatcccaaaatccatggggccattttggctgacagatcaaag
ccgcttcatcttcaacagcttgaacaattaggtatagaaacgatagacatggttgttgtc
aacctttatcctttcgaaaaaatgtacatcgcaaatgcttcagacgaagaaatgattgag
aacatagacataggtggtccaactttaattagagctgcggcgaaaaattacaaaaacgta
gctatcgtttgtgatccaaaggactatccaatcgttgttgatgaaatcaagcaatacggt
gaagtgagacttgaaacgaggttaaaacttgcccaaaaagctttcgaattgacttcttat
tacgattcaatcgtggctaggtacttccgagataaaacaaaagaaattttcccagagttt
ttaacgctgggcttcaaacttcaccaaaccttaaggtatggtgaaaatccacatcaaatg
gcggctgcttacgtcgatctcaggtatgaaggaacgataatggataccacacagctttgg
ggtaaagaactttctttcaacaacatagccgatgcagatgcggctttgagtatcgttaaa
gaattcacccagccctgcgcggtgggtgtaaagcataccaatccgtgtggtgtggcatgc
ggggaaactttgttggaggcttttgaaaagatgtacgaagctgatccaatatccatcttt
ggtggtatagtggctttaaacagaacagttgacgaaaaaacggccgaaaagatgtctcag
atctttcttgaggttgtaatagcaccggattacgatccgaaagctttggaaattttgatg
aaaaagaaaaatttgagaatacttaaagtgaaaatcgatagattgaaccaaaatgagctt
gatttaagaaaagtctcgggtggactacttgttcaaacaccagattcaacagattacaac
gaactgaggtgtgtgacgaaaagagaaccaacgccacaagaattggaagatcttctcttc
gcatggaaggtcgtcaaacacgtgaaatcaaacgccatcgtcttggcaaagaatcttgcc
acagttggaataggagctgggcaggtcaacagactctggccaactgaacactgtgtgaga
atagcaggtccaaaggcaaacggcgcggttttggcttccgacgccttctttccatttcca
gatgccgtcgaagttgcggcgaaagcaggagttaccgcgataatccaaccgggtggatcg
attcgagatgaagaagttatcaaagtggcaaatgaatacaacatcgccatgattttcacc
ggaacaaggcattttaaacactga

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