Pseudothermotoga thermarum: Theth_1815
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Entry
Theth_1815 CDS
T01554
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tta
Pseudothermotoga thermarum
Pathway
tta00300
Lysine biosynthesis
tta00550
Peptidoglycan biosynthesis
tta01100
Metabolic pathways
tta01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tta00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Theth_1815
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Theth_1815
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Theth_1815
Enzymes [BR:
tta01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Theth_1815
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEH51857
UniProt:
F7YW85
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Position
1838446..1839723
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AA seq
425 aa
AA seq
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MLLDLFENTTFVIDSRKVVPGCVFVALKGEKTDGHLYVREALEKGAKLAVVEKQVDAPSD
KLVFVPSTVDFLAQLASYRLSKHNPLVIGITGSNGKTTTKEILFKLLENYGPFRNEGNLN
TEIGLPLSIINGYLGQKIVILEMAMNKVGDIAKLCQVARPRIAVLLNVGSAHRGVAGGDE
AILRGKLEIVENMAVDGTAVVLDDERIVSRIKGKNCVTFGYLKGDYQLISFEYKNLKTIT
VYSAKGKILKVELSNIWNTGQLTNLAAVFAVLDLLGLEVDLKKLEEFDFVPGRFKLVECK
GIYIFDDCYNASLESFKVAVDTIKKVGKRAFAVVGSIKEQGEFSNQTHLELGKILEQLDG
VIVYTKEPEIEVMKCSKEILRTSIVDEIVQKLSDILKAEDAVLFKASRAVEMEKVLQRFL
EVLKC
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgttgcttgatttgtttgaaaacacaacttttgtaattgactcaagaaaggttgttcca
ggttgtgtttttgttgcgctaaaaggagaaaaaactgatggtcatctttacgtgagggaa
gctcttgaaaaaggggcaaaacttgctgtagtggagaagcaagttgatgcacctagcgac
aaacttgttttcgtgccaagtactgttgattttcttgctcaattggcttcttataggctt
tcaaagcacaatcctttagttataggcatcactggatctaacggaaaaaccacaaccaag
gaaattttgttcaaacttttggaaaattatggtccttttcgaaatgaaggaaacttgaat
accgagataggccttcctttatccatcatcaacggttatcttgggcaaaaaatagtgatt
ttggaaatggctatgaacaaggtgggagatatcgcaaaactatgccaagtggctaggcca
aggatagcagttttgctgaacgttggaagtgcacacagaggggttgcaggaggagatgag
gcaattttgagaggaaaacttgagatcgttgaaaacatggcggtagatggaacagcagtt
gttttggatgacgagcgaattgtttcaagaattaagggcaaaaactgcgttacctttggt
tatttgaagggagattatcaactgatttcctttgaatacaaaaacttaaaaacgataacg
gtttattctgccaaaggaaaaattttaaaagttgaattaagcaatatttggaacacaggt
cagcttacaaaccttgcggctgttttcgccgttttggatcttttgggtttggaagttgat
ttgaaaaaacttgaagaatttgactttgtgcctggtcgattcaaacttgttgagtgcaaa
ggtatttacatttttgacgattgttacaacgctagcttggagtctttcaaagttgccgtt
gataccatcaagaaagttggtaagagggcttttgcagttgttggttccataaaggaacaa
ggggaattttcaaatcaaactcatcttgaacttggaaagattttggaacagcttgacggt
gtgatcgtgtatacaaaagaaccggagatagaagtgatgaagtgctcaaaggaaattttg
cgaacatcgatcgttgatgagattgttcaaaagttgagtgatattctcaaggctgaagat
gccgtgttgttcaaagcatccagagcagttgaaatggaaaaggttttgcagagatttttg
gaggtgttgaaatgttaa
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