Thermus thermophilus HB27: TT_C0714
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Entry
TT_C0714 CDS
T00170
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-L-ornithine-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tth
Thermus thermophilus HB27
Pathway
tth00300
Lysine biosynthesis
tth00550
Peptidoglycan biosynthesis
tth01100
Metabolic pathways
tth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tth00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TT_C0714
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TT_C0714
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TT_C0714
Enzymes [BR:
tth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TT_C0714
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
wHTH-HSP90_Na-assoc
Motif
Other DBs
NCBI-ProteinID:
AAS81062
UniProt:
Q72JQ4
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All DBs
Position
698958..700274
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AA seq
438 aa
AA seq
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MLKGGEDVVQGTHVRELTPEWVARAVGGRLHPGGGPVRDLVWHSGAATPGSLFAALPGRT
THGRHFIPEALARGASLVLADQAGPATLEVEDPWQALLRLGEALRRLFPGPVLAVGGSSG
KTTTKEALAQGLGLPAPPGNLNTAPPLVRFFWHLDPQSPGAVVELGVDRQGEMAELFALA
KPHLAVLTALGEEHLEAFGTLEKAVQEEAHLLRAPTALVGEQAAPLVLGLREDLLVYGFA
EGTFRGRDLELGLRESRFRYGGLHVRVPYPGLGPAYGALAALAAAEVLGLSLEEVAERLS
RLTLPPGRMETREVGGVVFVNDAYNANPLSVKAGLRWLAAQPGRKWAVLGEMRELGRESL
RLHLEVAEEAARLGLSPLYLGPHARHQAAFSGEAVESLEEALAWLKARVAPGDLVYLKAS
RAVGLERIVELWDAPFSS
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atgctgaagggcggtgaggatgttgtgcaagggacgcatgttagggaactaacgccggag
tgggtggcccgggccgtggggggacggctccatccgggcggagggccggtgcgggacctg
gtctggcacagcggcgccgccacgccgggaagcctcttcgccgccctccccgggcgcacc
acccacgggcggcatttcatcccggaggccctggcccggggggcaagcctggtcctggcc
gaccaggcgggccccgccaccctggaggtggaggacccctggcaggccctcctgcgcctg
ggcgaggccctccgccgcctcttcccgggcccggtcctggccgtggggggaagctcgggc
aagaccaccaccaaggaggccctggcccagggcctgggccttcccgcccccccggggaac
ctcaacaccgccccgccccttgtccgcttcttctggcacctggacccccaaagccccggg
gccgtggtggagctcggcgtggaccgccagggggagatggcggagctcttcgccctggcg
aagccccacctcgccgtcctcaccgccctcggggaggagcacctggaggccttcggcacc
ctggagaaggcggtgcaggaggaggcccacctcctccgggcccccaccgccttggtgggc
gagcaggccgcccccctcgtcctagggctcagggaagacctcctcgtctacgggttcgcc
gagggcaccttccggggacgggacctggagctcggcctccgggaaagccgcttccgctac
ggaggccttcacgtgcgcgttccctaccccgggctgggccccgcctacggggcgctcgcg
gccctggcggcggccgaggtcctgggcctttccctggaagaggtggcggaaaggctctcc
cgcctcaccctccccccggggcgcatggagacgcgggaggtgggcggcgtggtcttcgtc
aacgacgcctacaacgccaaccccctttcggtgaaggccggcctccgctggctcgccgcc
cagccggggcggaagtgggccgtgctcggggagatgcgggagctcggcagggaaagcctc
cgcctccacctcgaggtggcggaggaggcggcgaggctgggcctctcccccctctacctg
gggccccacgcccggcaccaggccgccttctccggcgaggcggtggagagcctggaggaa
gccctggcctggctcaaggcccgggtggccccgggggacctcgtctacctcaaggcctcc
agggccgtgggcctggagcggatcgtggagctatgggacgcgcccttctcctcctag
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