Thermus thermophilus HB8: TTHA0489
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Entry
TTHA0489 CDS
T00220
Symbol
TTHA0489
Name
(GenBank) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00260
Glycine, serine and threonine metabolism
ttj00270
Cysteine and methionine metabolism
ttj00300
Lysine biosynthesis
ttj01100
Metabolic pathways
ttj01110
Biosynthesis of secondary metabolites
ttj01120
Microbial metabolism in diverse environments
ttj01230
Biosynthesis of amino acids
Module
ttj_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
TTHA0489 (TTHA0489)
00270 Cysteine and methionine metabolism
TTHA0489 (TTHA0489)
00300 Lysine biosynthesis
TTHA0489 (TTHA0489)
Enzymes [BR:
ttj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
TTHA0489 (TTHA0489)
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
BAD70312
UniProt:
Q5SL04
Structure
PDB
PDBj
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All DBs
Position
1:457462..458460
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AA seq
332 aa
AA seq
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MEALKIALLGGGTVGSAFYNLVLERAEELSAFGVVPRFLGVLVRDPRKPRAIPQELLRAE
PFDLLEADLVVEAMGGVEAPLRLVLPALEAGIPLITANKALLAEAWESLRPFAEEGLIYH
EASVMAGTPALSFLETLRGSELLELHGILNGTTLYILQEMEKGRTYAEALLEAQRLGYAE
ADPTLDVEGIDAAHKLTLLARLLVDPGFPFAEVEAQGIARLTPEVLQKAEARGERVRLVA
SLFGEGGRWRAAVAPRRLPQDHPLARARGNALWVRARPLGEAFVTGPGAGGGATASGLFA
DLLRFLSGAPGHLPAPRARPPLEEGSPWPGVE
NT seq
999 nt
NT seq
+upstream
nt +downstream
nt
atggaggccttaaagatcgccctcttggggggcggcaccgtggggagcgccttctacaac
ctcgtgttggagcgggcggaggagctttccgccttcggggtcgtcccccgtttcctcggc
gtcttggtgcgggacccgaggaagcccagggccatcccccaggaacttcttcgcgccgag
ccctttgacctcctggaggccgacctggtggtggaggccatggggggggtggaggccccc
cttaggctcgtcctccccgccctcgaggccggcatccccctcatcaccgccaacaaggcc
ctcctcgccgaggcctgggagtccttaaggcccttcgccgaggaggggctcatctaccac
gaggcgagcgtcatggcgggcacccccgccctctccttcctggagaccctgaggggaagc
gagcttctggagctccacggcatcctgaacggcaccaccctctacatcctccaggagatg
gagaagggccggacctacgccgaggcgcttcttgaggcccagcgcctgggctacgccgag
gccgaccccaccttggacgtggaggggatagacgccgcccacaagctcaccctcctcgcc
cggctcctcgtggaccccggcttccccttcgccgaggtggaggcccaaggcatcgcccgc
ctcaccccagaggtcctgcaaaaggccgaggcccggggggagcgggtgcgcctcgtggcg
agcctcttcggggaaggggggaggtggcgggcggcggtggccccaaggcgccttccccag
gaccaccccttggcgagggcccggggaaacgccctctgggtccgggccaggcctttgggg
gaggccttcgtcacggggcctggggcggggggcggggccacggcgagcgggcttttcgcc
gacctcctccgcttcctctccggggccccggggcacctccctgccccccgggcgaggccc
cctttggaggagggaagcccctggccgggggtagaatga
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