Thermus thermophilus HB8: TTHA0545
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Entry
TTHA0545 CDS
T00220
Symbol
TTHA0545
Name
(GenBank) aspartate-semialdehyde dehydrogenase
KO
K00133
aspartate-semialdehyde dehydrogenase [EC:
1.2.1.11
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00260
Glycine, serine and threonine metabolism
ttj00261
Monobactam biosynthesis
ttj00270
Cysteine and methionine metabolism
ttj00300
Lysine biosynthesis
ttj01100
Metabolic pathways
ttj01110
Biosynthesis of secondary metabolites
ttj01120
Microbial metabolism in diverse environments
ttj01210
2-Oxocarboxylic acid metabolism
ttj01230
Biosynthesis of amino acids
Module
ttj_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
TTHA0545 (TTHA0545)
00270 Cysteine and methionine metabolism
TTHA0545 (TTHA0545)
00300 Lysine biosynthesis
TTHA0545 (TTHA0545)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
TTHA0545 (TTHA0545)
Enzymes [BR:
ttj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.11 aspartate-semialdehyde dehydrogenase
TTHA0545 (TTHA0545)
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Motif
Pfam:
Semialdhyde_dhC
Semialdhyde_dh
Gp_dh_C
Semialdhyde_dhC_1
DapB_N
S4
Ldh_1_N
Motif
Other DBs
NCBI-ProteinID:
BAD70368
UniProt:
Q5SKU8
Structure
PDB
PDBj
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Position
1:509255..510250
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AA seq
331 aa
AA seq
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MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPVEPLPEGPL
PVDLVLASAGGGISRAKALVWAEGGALVVDNSSAWRYEPWVPLVVPEVNREKIFQHRGII
ANPNCTTAILAMALWPLHRAFQAKRVIVATYQAASGAGAKAMEELLTETHRFLHGEAPKA
EAFAHPLPFNVIPHIDAFQENGYTREEMKVVWETHKIFGDDTIRISATAVRVPTLRAHAE
AVSVEFARPVTPEAAREVLKEAPGVEVVDEPEAKRYPMPLTASGKWDVEVGRIRKSLAFE
NGLDFFVVGDQLLKGAALNAVQIAEEWLKGA
NT seq
996 nt
NT seq
+upstream
nt +downstream
nt
atgagggtagccgtggtgggggccacgggggccgtggggcgggagatcctcaaggtcctc
gaggcccgaaacttccccctttcggagctcaggctctacgcctctccccgttccgccggg
gtgcgcctcgcgttcaggggcgaggagatccccgtggagcccctacccgaggggcctctc
cctgtggacctcgtcctggcgagcgccggggggggcatctccagggccaaggccttggtc
tgggcggagggcggggccttggtggtggacaactccagcgcctggcgctacgagccctgg
gtgcccctggtggtgcccgaggtgaaccgggagaagatcttccagcaccgggggatcatc
gctaaccccaactgcaccacggccattttggccatggccctttggcccttgcaccgggcc
ttccaggccaagcgggtcatcgtggccacctaccaggcggcttccggggccggggccaag
gccatggaggagctccttaccgaaacccaccgcttcctccacggggaggcccccaaggcc
gaggccttcgcccaccccctgcccttcaacgtcatcccccatatagacgccttccaggag
aacggctacacccgcgaggagatgaaggtggtctgggagacccacaagatcttcggagac
gacaccatccggatcagcgccacggcggtgcgggtgcccaccttaagggcccacgccgag
gcggtgagcgtggagtttgcccgccccgtgaccccggaggcggcccgggaggtcctcaag
gaggccccgggggtggaggtggtggacgagcccgaggccaagcgctaccccatgcccctc
accgcgagcggcaagtgggacgtggaggtggggaggatccggaaaagcctcgcctttgaa
aacggcctggacttcttcgtggtgggggaccagctcttgaagggggccgccttaaacgcc
gtgcagatcgccgaggagtggcttaagggcgcctga
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