Thermus thermophilus HB8: TTHA1079
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Entry
TTHA1079 CDS
T00220
Symbol
TTHA1079
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00300
Lysine biosynthesis
ttj00550
Peptidoglycan biosynthesis
ttj01100
Metabolic pathways
ttj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TTHA1079 (TTHA1079)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TTHA1079 (TTHA1079)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TTHA1079 (TTHA1079)
Enzymes [BR:
ttj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TTHA1079 (TTHA1079)
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
wHTH-HSP90_Na-assoc
HTH_AsnC-type
Motif
Other DBs
NCBI-ProteinID:
BAD70902
UniProt:
Q5SJD5
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All DBs
Position
1:1025984..1027300
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AA seq
438 aa
AA seq
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MLKGGEDVVQGTHVRELTPEWVARAVGGRLHPGGGPVRDLVWHSGAATPGSLFAALPGRT
THGRHFIPEALARGASLVLADQAGPATLEVEDPWQALLRLGEALRRLFPGPVLAVGGSSG
KTTTKEALAQGLGLPAPPGNLNTAPPLVRFFWHLDPQSPGAVVELGVDRQGEMAELFALA
KPHLAVLTALGEEHLEAFGTLEKAVQEEAHLLRAPTALVGEQAAPLVLGLREDLLVYGFA
EGTFRGRDLELGLRESRFRYGGLHVRVPYPGLGPAYGALAALAAAEVLGLSLEEVAERLA
RLTLPPGRMETREVGGVVFVNDAYNANPLSVKAGLRWLAAQPGRKWAVLGEMRELGRESL
RLHLEVAEEAARLGLSPLYLGPHARHQAAFSGEAVESLEEALAWLKARVAPGDLVYLKAS
RAVGLERIVELWDAPFSS
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atgctgaagggcggtgaggatgttgtgcaagggacgcatgttagggaactaacgccggag
tgggtggcccgggccgtggggggacggctccatccgggcggagggccggtgcgggacctg
gtctggcacagcggcgccgccacgccgggaagcctcttcgccgccctccccgggcgcacc
acccacgggcggcatttcatcccggaggccctggcccggggggcaagcctggtcctggcc
gaccaggcgggccccgccaccctggaggtggaggacccctggcaggccctcctgcgcctg
ggcgaggccctccgccgcctcttcccgggcccggtcctggccgtggggggaagctcgggc
aagaccaccaccaaggaggccctggcccagggcctgggccttcccgcccccccggggaac
ctcaacaccgccccgccccttgtccgcttcttctggcacctggacccccaaagccccggg
gccgtggtggagctcggcgtggaccgccagggggagatggcggagctcttcgccctggcg
aagccccacctcgccgtcctcaccgccctcggggaggagcacctggaggccttcggcacc
ctggagaaggcggtgcaggaggaggcccacctcctccgggcccccaccgctttggtgggc
gagcaggccgcccccctcgtcctggggctcagggaagacctcctcgtctacgggttcgcc
gagggcaccttccggggacgggacctggagctcggcctccgggaaagccgcttccgctac
ggaggccttcacgtgcgcgttccctaccccgggctgggccccgcctacggggcgctcgcg
gccctggcggcggccgaggtcctgggcctttccctggaagaggtggcggaaaggctcgcc
cgcctcaccctccccccggggcgcatggagacgcgggaggtgggcggcgtggtcttcgtc
aacgacgcctacaacgccaaccccctttcggtgaaggccggcctccgctggctcgccgcc
cagccggggcggaagtgggccgtgctcggggagatgcgggagctcggcagggaaagcctc
cgcctccacctcgaggtggcggaggaggcggcgaggctgggcctctcccccctctacctg
gggccccacgcccggcaccaggccgccttctccggcgaggcggtggagagcctggaggaa
gccctggcctggctcaaggcccgggtggccccgggagacctcgtctacctcaaggcctcc
agggccgtgggcctggagcggatcgtggagctatgggacgcgcccttctcctcctag
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