Thermus thermophilus JL-18: TtJL18_0523
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Entry
TtJL18_0523 CDS
T02009
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00230
Purine metabolism
ttl01100
Metabolic pathways
ttl01110
Biosynthesis of secondary metabolites
Module
ttl_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
TtJL18_0523
Enzymes [BR:
ttl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
TtJL18_0523
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AFH38429
UniProt:
H9ZQ19
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All DBs
Position
complement(460230..462407)
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AA seq
725 aa
AA seq
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MEALAKEIGIPEGEYREIVQRLGREPNRVELLLFKVMWSEHCAYKNSRPLLKALPKEGEA
VLQGPGENAGVVRVGEGWAVAFKIESHNHPSAVEPFQGAATGVGGILRDIMSMGARPIAL
LDSLRFGPPEEARSRYLLKGVVSGIAFYGNAIGVPTVGGDLYFHEGYRENPLVNAMCLGL
LREEHLKRSRASLGRPIYYAGAKTGRDGIGGAAFASRELKEEKAEDRPAVQVGDPFLGKL
LMEATLEAIELDLVEGVQDMGAAGLTSSLSELAHKSGLGVELHLDLVPTREEGMTPEELL
LSESQERMVLVPKEGKEKALEEVFGRWGLDCVPVARTIPERVFRVLFRGEVVAEVPTEAL
AEAPTYVRVGREDPEVRRLRETPIPPLEADPQEVLRRLLASPNLASREAVYERYDHQVGT
RTALLPGKGDAVVLWIKGTRLGVAAKVDQNPRYSRLHPRLGAMHALAEACRNVSVVGAKP
LAYTDGLNLGSPETPEGYHELAETIAGLKEASEALGVPVVSGNVSLYNESGGKRIPPTAM
VGVVGVLEVDKRAEMGFRRPGEVLLLIGEERGELGASEVLYLLTGKEFGHPPRLDLRREK
AVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFPYGVGATVEVREEGLEALFGEAPSR
VLFTVEKARLQEATLLLEERGLPYRVLGETGGKSLTVLTPGGVLEWSLEELLSAWKAPLR
EVLDG
NT seq
2178 nt
NT seq
+upstream
nt +downstream
nt
atggaggccctcgccaaggagatcgggatcccggaaggggagtaccgggagatcgtccag
aggctcgggcgggagccgaaccgggtggagctcctcctcttcaaggtgatgtggagcgag
cactgcgcctacaagaactcccgccccctcctcaaggccctccccaaggagggggaggcc
gtcctccagggccccggggagaacgccggcgtggtgcgggtgggcgagggttgggccgtg
gccttcaagatagagagccacaaccacccctcggcggtggagcccttccagggggcggcc
acgggggtcggggggatcctccgggacatcatgagcatgggagcccgccccatcgccctc
ctggactccctccgcttcgggccccccgaggaggcgagaagccgctacctcctcaagggg
gtggtctcgggcatcgccttttacggcaacgccatcggagtgcccacggtgggcggggac
ctttacttccacgagggctaccgggaaaaccccctggtgaacgccatgtgcctcggcctc
ctgagggaggagcacctgaagcgaagccgggcctctttgggccgccccatctactacgcc
ggggccaagacgggccgggacgggatcggcggggcggccttcgcgagccgggagctcaag
gaggagaaggccgaggaccggcccgcggtccaggtgggggaccccttcctgggcaagctc
ctcatggaggccaccctcgaggccatagaactggacctggtggaaggcgtccaggacatg
ggggcggcggggctcaccagtagcctctcggagctcgcccacaagtcgggcctcggggtg
gagctccacctggacctcgtccccacccgggaggaggggatgaccccggaggagctcctt
ctctcggaaagccaggagcggatggtcctcgttcccaaggaggggaaggaaaaggccctg
gaggaggtcttcggaaggtggggcctagactgcgtacccgtggccaggaccatcccggaa
agggtcttccgggtcctctttaggggcgaggtggtggcggaggtgcccacggaggccttg
gccgaagcccccacctacgtgcgggtggggcgggaggaccccgaggtgcggaggcttagg
gaaacccccatcccccccttagaggccgacccccaggaggtcctaaggaggctcctcgcc
tcccccaacctggcgagccgggaggcggtctacgagcggtacgaccaccaggtggggacc
cgcaccgccctcctccccggcaaaggggacgccgtggtcctctggatcaagggcacccgc
ctcggcgtcgccgccaaggtggaccaaaacccccgctatagccgcctccacccccgcctt
ggggccatgcacgccctggcggaggcctgccggaacgtcagcgtggtgggggcgaagccc
ctcgcctacaccgacggcctcaacctgggaagcccggagaccccggagggctaccacgag
ctcgccgagaccatcgccgggctcaaggaggcgagcgaggccttgggcgtccccgtggtc
tcggggaacgtctccctctacaacgaaagcgggggcaagcgcatcccccccacggccatg
gtgggggtggtgggggtcctggaggtggacaagcgggcggagatgggctttaggcgcccg
ggggaggtcctcctcctcatcggggaggaacggggggagcttggggcgagcgaggtcctc
tacctcctcacgggaaaggagttcggccaccccccaaggcttgacctcaggcgggaaaag
gcggtgcaggaggcgatccgggacctcatccaaaggggcctcacccgaacggcccacgac
gtggcggaaggggggcttcttctggccctcgccgagatgaccttcccctacggggtgggg
gccacggtggaggtgcgggaggagggcctcgaggccctcttcggcgaggccccaagccgc
gtcctcttcaccgtggagaaggcccgcctccaggaggccaccctcctcctggaggagcgg
ggcctcccctaccgggtcctgggggagacgggggggaagagcctcacggtcctcaccccg
gggggtgtcctagagtggagcctggaggaactgctttccgcctggaaagcgcccctcagg
gaggtgctggatggataa
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