Thermus thermophilus JL-18: TtJL18_0981
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Entry
TtJL18_0981 CDS
T02009
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ttl
Thermus thermophilus JL-18
Pathway
ttl00300
Lysine biosynthesis
ttl00550
Peptidoglycan biosynthesis
ttl01100
Metabolic pathways
ttl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ttl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TtJL18_0981
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TtJL18_0981
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TtJL18_0981
Enzymes [BR:
ttl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TtJL18_0981
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
wHTH-HSP90_Na-assoc
Motif
Other DBs
NCBI-ProteinID:
AFH38881
UniProt:
H9ZRC1
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Position
complement(893758..895074)
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AA seq
438 aa
AA seq
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MLKGGEDVVQGTYVRELTPEWVARAVGGRLHPGGGPVRDLVWHSGAATPGSLFAALPGRT
THGRHYIPEALARGASLVLADRAGPATLEVEDPWKALLRLGEALRRLFPGPVLAVGGSSG
KTTTKEALAQGLGLPAPPGNLNTAPPLVRFFWHLDPQSPGAVVELGVDRQGEMAELFALA
KPHLAVLTALGEEHLEAFGTLKKAVEEEAHLLRAPTALVGEQAAPLVLGLREDLLVYGFA
EGTFRGRELELGLRESRFRYGGLHVRVPYPGLGPAYGALAALAAAEVLGLSLEEVAERLS
RLTLPPGRMEMREVGGVTFVNDAYNANPLSVKAGLRWLAAQPGRKWAVLGEMRELGRESL
RLHLEVAEEAARLGLSPLYLGPHARHQAAFSGEAAESLEEALAWLKARVAPGDLVYLKAS
RAVGLERIVELWDAPFSS
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atgctgaagggcggtgaggatgttgtgcaagggacgtatgttagggaactaacgccggag
tgggtggcccgggccgtggggggacggctccatccgggcggagggccggtgcgggacctg
gtctggcacagcggcgccgccacgccgggaagcctcttcgccgccctccccggtcgtacc
acccacgggcggcactacattccggaggccctggcccggggggcaagcctggtcctggcc
gaccgggcaggccccgccaccctggaggtggaggacccctggaaggccctcctgcgcctg
ggcgaggccctccgccgcctcttcccgggcccggtcctggccgtggggggaagctcgggc
aagaccaccaccaaggaggccctggcccagggcctgggccttcccgcccccccggggaac
ctcaacaccgccccgcccctcgtccgcttcttctggcacctggacccccaaagccccggg
gccgtggtggagctcggcgtggaccgtcagggggagatggcggagctcttcgccctggca
aaaccccacctcgccgtcctcaccgccctcggggaggagcacctggaggccttcgggacc
ctgaaaaaggcagtagaggaagaggcccacctcctccgggcccccaccgccttggtgggg
gagcaggccgcccccctcgtcttgggcctcagggaagacctcctcgtctacgggttcgcc
gagggcaccttccggggacgggagttggagctcggcctccgggaaagccgcttccgctac
ggaggccttcacgtgcgcgttccctaccccgggcttggccccgcctacggggcgcttgcg
gccctggcggcggccgaggtcttgggcctttccctggaagaggtggcggaaaggctctcc
cgcctcaccctccccccggggcgcatggagatgcgggaggtgggcggcgtgacctttgtc
aacgacgcctacaacgccaaccccctttcggtgaaggccggcctccgctggctcgccgcc
cagccggggcggaagtgggccgtgctcggggagatgcgggagcttggccgggaaagcctc
cgcctccacctcgaggtggcggaggaggcggcgaggctgggcctctcccccctctacctg
gggccccacgcccggcaccaggccgccttctctggcgaggcggcggagagcctggaggaa
gccctggcctggctcaaggcccgggtggccccgggggacctcgtctacctcaaggcctcc
agggccgtgggcctggagcggatcgtggagctatgggacgcgcctttctcctcctag
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