Thermoanaerobacterium thermosaccharolyticum DSM 571: Tthe_0014
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Entry
Tthe_0014 CDS
T01299
Name
(GenBank) pyruvate carboxyltransferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ttm
Thermoanaerobacterium thermosaccharolyticum DSM 571
Pathway
ttm00290
Valine, leucine and isoleucine biosynthesis
ttm00620
Pyruvate metabolism
ttm01100
Metabolic pathways
ttm01110
Biosynthesis of secondary metabolites
ttm01210
2-Oxocarboxylic acid metabolism
ttm01230
Biosynthesis of amino acids
Module
ttm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tthe_0014
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tthe_0014
Enzymes [BR:
ttm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tthe_0014
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Motif
Pfam:
HMGL-like
HCS_D2
FlpD
Motif
Other DBs
NCBI-ProteinID:
ADL67612
UniProt:
D9TMD5
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Position
14160..15353
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AA seq
397 aa
AA seq
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MGDRKVIVFDTTLRDGEQTPGVNFDKDSKYRIAKQLVSLGVDVIEAGFPAASNGNFEAVK
HIAENIDDVVVAGLSRCVKSDIDKTYEALKNAKKSRIHLFIATSDIHLKYKLKISRDEAL
KMAVDSVKYASGKFDEIQFSAEDASRTDWDFLVKIFNEVVDAGAKIINIPDTVGYAVPKE
FEKLVEYVKKHIHDKDNVTISVHCHNDLGMAVVNSLSALENGADQVEVTVCGIGERAGNA
SLEEVIMAINTRKDYFNLLHSINTREIFSTCKLVSELSGIDLQPNKAIVGSNAFRHTAGI
HQHGVINNKATYEIMRPEDIGITTDHISMGKLSGRNAFELKLKNMGYELSRDEMNLAFKK
FKDVADNKKIVNDNEIKAIVDDVISNSKSIKEGELWG
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
atgggggatagaaaagtcattgtatttgatacaacattaagagatggtgagcaaacacct
ggtgtgaactttgacaaagacagtaaatatagaatagcaaaacagcttgtttcacttggt
gtagatgttatagaagctggttttcctgctgcatcaaacggcaacttcgaagctgtaaag
catatagcagaaaatattgatgatgtagttgtggcaggattatcaagatgtgtaaaaagt
gatatagataaaacttatgaagcactgaaaaatgccaaaaaatcaagaatacatcttttc
atagcaacatctgatattcatttgaaatacaaattaaaaatatccagagatgaagcatta
aaaatggctgttgacagtgtaaaatatgcttcaggtaaatttgacgagatacaattttct
gcagaagatgcttcaaggacagattgggattttcttgtgaaaatatttaatgaagttgtt
gatgcgggagcaaaaataatcaatatacctgacactgtaggctatgcggttccaaaagaa
tttgaaaagttagtagaatacgttaaaaagcatatacatgataaagacaatgttacaata
agcgttcactgtcacaatgaccttggaatggctgttgtgaattccctttcagcattggaa
aacggtgctgatcaagtggaagtaactgtgtgcggaataggtgagagagcaggaaatgca
tcgctggaagaagttattatggcaataaatacgcgaaaagattatttcaatttacttcac
agtataaatacaagagaaatatttagtacctgcaaacttgtaagtgaactttcaggcatc
gatctacaacctaataaagcgattgtaggttctaatgcatttagacacactgctggaatt
caccagcatggcgtgataaacaataaagcaacgtatgaaataatgaggcctgaagatata
ggtataactacagatcatatatctatggggaagctatctggcagaaatgcctttgaactg
aaattaaaaaatatgggatatgaactttcacgtgatgaaatgaacttagcttttaaaaag
tttaaagatgtagctgataataagaaaattgtaaatgacaatgaaataaaagcgattgta
gatgatgttatttcgaattcgaaaagtatcaaggagggagagctttggggttaa
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