Thermoanaerobacterium thermosaccharolyticum DSM 571: Tthe_1770
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Entry
Tthe_1770 CDS
T01299
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ttm
Thermoanaerobacterium thermosaccharolyticum DSM 571
Pathway
ttm00300
Lysine biosynthesis
ttm00550
Peptidoglycan biosynthesis
ttm01100
Metabolic pathways
ttm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ttm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tthe_1770
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tthe_1770
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tthe_1770
Enzymes [BR:
ttm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tthe_1770
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2608
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
ADL69267
UniProt:
D9TR15
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All DBs
Position
complement(1762719..1764092)
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AA seq
457 aa
AA seq
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MILSVKEIIDATSGKLLSGDINSTISGISTDSRTIKEGELFIPLKGENFNGEMFVEDALK
IGSASLTESVNNVGRYNKPVIFVDNTKEALHKIAKYYREKFQIPFIAVTGSNGKTTTKDM
IYDVLSMKYNVLKTQGNFNNEIGLPLTIFRLNKKHDMAIVEMGMSGFGEIRRLKNIADPN
VAVYTNIGVAHIEKLGSRENILKAKSELVENFKEGYTVILNADDDMLVKLTNKKGPQYIT
YGIDNGDVKAFDIEYKEESVKYKVIIDGYMMDVELNVPGKHNVYNSLAAICIGIKFGVNK
EDMRKALAEFQPSAMRLNILDVSGIKVINDAYNANPGSMKAALSVLKEYKDRRKVAVLGN
MLELGEYSDLAHEEVGKYVKDENIDVLITVGEFASKIAEGAIKSGMDVENVMICKNNVEA
YEKIKKIMRNNDVFLIKGSRGMKMEEIVKFLQESANK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
ttgattttaagcgtaaaagaaataattgatgctacaagtggaaaattactatcaggagac
ataaattcgactataagtggtataagtacagattctaggacaataaaagaaggtgagctt
tttataccgcttaaaggtgaaaattttaatggtgaaatgtttgttgaagatgcccttaaa
ataggttctgcttcacttacagaatcagtaaataatgttggtaggtacaataagccagta
atatttgttgataatacaaaagaggctttacacaagatagcaaaatattatcgtgaaaaa
tttcaaataccttttatagctgttacaggaagcaacggaaaaactactacaaaagacatg
atatacgatgttttgtctatgaaatacaatgttttaaagactcagggaaactttaataat
gagataggattgcctcttaccatattcaggttgaataaaaagcacgacatggctattgtt
gaaatgggaatgagcggttttggagaaattaggagacttaaaaacatagctgaccctaat
gtcgcggtgtacacaaatatcggtgttgcccatattgaaaaattgggttctcgtgaaaat
atattaaaagcaaaatctgagttggtggaaaattttaaagagggctatacagttatactt
aatgcagatgacgatatgcttgtaaaattaactaataaaaaaggtcctcaatacattaca
tatggtatagataatggagatgtaaaagcttttgacatagaatacaaagaagaatctgtg
aagtataaagtcataattgacggatatatgatggatgtagaattgaatgtgcccggaaag
cacaatgtatacaattctttagcagcaatttgtataggaattaaatttggtgtcaataaa
gaagatatgagaaaagcactagctgagtttcaaccaagtgccatgaggcttaatatacta
gatgtatcaggaataaaagtaataaatgatgcatacaacgcgaatccgggatctatgaag
gctgctttatcagttttgaaagagtacaaagatagaaggaaagtggctgttctgggcaat
atgttagagcttggagagtactctgatttagcacatgaagaagtggggaaatatgtaaaa
gatgaaaacatagatgtacttataacggttggagaatttgcatctaaaatagctgaggga
gcaataaaaagcggaatggatgtagaaaatgtaatgatatgcaaaaataatgttgaagct
tacgagaagataaaaaaaattatgagaaataatgatgtttttttaataaagggatctaga
ggaatgaaaatggaggaaatcgtgaagttcttacaggagagtgctaataaatga
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