Thermoanaerobacterium thermosaccharolyticum M0795: Thethe_02083
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Entry
Thethe_02083 CDS
T02407
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tto
Thermoanaerobacterium thermosaccharolyticum M0795
Pathway
tto00290
Valine, leucine and isoleucine biosynthesis
tto00620
Pyruvate metabolism
tto01100
Metabolic pathways
tto01110
Biosynthesis of secondary metabolites
tto01210
2-Oxocarboxylic acid metabolism
tto01230
Biosynthesis of amino acids
Module
tto_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tto00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Thethe_02083
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thethe_02083
Enzymes [BR:
tto01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Thethe_02083
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AGB19674
UniProt:
L0ILM9
LinkDB
All DBs
Position
complement(2050320..2051879)
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AA seq
519 aa
AA seq
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MKNVVIYDSTLRDGAQSQGISFTVADKIKIVELLDEFGIDYIEAGNPGSNPKDMEFFEII
KSKKLKNAKVIAFGSTRRANIPVEIDNNVNSLLHAGTDHVAVFGKSWDFHVSEILRTTLD
ENLNMIFDTIKYLKNHGKEVVFDAEHFFDGFLENPEYALKTLEVAYDAGADSICLCDTKG
GMFPLDIFNITKKVVEKFNCEIGIHTHNDNGMAVANAIMAVEAGATQIQGTINGYGERCG
NANLCTIIPNLQFKKGIKCVEDEKMKEITILSRRVSEIANAAPDERAPYVGRSAFAHKAG
MHSDAVCKNTRSYEIIDPEMVGNERVLLLSEVAGRSAIIGIINEVDPTINRESEKTKRIL
EKLKEMEFKGYKYEGAEGSLKLLIQKVLGMYKPSFKLIEFKVIVNEPSVDDVNSSALIKI
EVDGQEEITAAEGDGPVNALDNAVRKALERFYPEVKEMKLTDYKVRVLDSNSATAAKVRV
IIESSDGNEVWSTIGVSTDIIDASWIALVDSIEYKLNKI
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
gtgaaaaatgttgttatttatgattcaacattaagagatggtgcgcaatcacaggggatt
tcatttacagtggcagacaagataaagatagtggagcttttagacgagtttggaatagac
tatatcgaagctggaaatcccggttcaaatccaaaggacatggagttttttgaaattata
aagagtaaaaagttaaaaaatgcaaaagtgatcgcatttggcagtactagaagggctaac
atacctgttgaaattgacaacaatgtaaattcgcttttacacgccggaacagatcatgtt
gcagtattcggcaagtcgtgggattttcatgtaagtgaaatattaaggacgacgcttgat
gaaaatctcaatatgatatttgatacgataaaatatttaaaaaatcatggaaaagaagtt
gtgttcgatgccgaacatttttttgatggttttttagagaatccagaatatgcattgaaa
acccttgaagttgcatacgatgcaggtgcggatagtatttgcttgtgtgatacaaaaggc
gggatgtttccgctggacatttttaatataacgaaaaaggtagttgaaaaatttaattgt
gaaattggtatacacacacataatgacaatggcatggctgttgcaaatgctataatggca
gttgaagcaggtgcaacacaaattcaaggtacaataaacggatatggtgaaagatgcgga
aatgcaaatctctgtacaataataccaaacttgcagtttaaaaaagggataaagtgtgtt
gaagatgaaaaaatgaaagaaataacgatactttccagaagagtaagcgaaatagcaaat
gccgcaccggatgaaagggctccatacgttggtagaagcgcatttgcccacaaagcaggt
atgcattccgatgctgtatgcaaaaatactagatcgtatgagataatcgatcctgaaatg
gtaggcaatgaaagagtacttttactatcagaagttgccggcagaagtgctataataggg
ataataaatgaagttgatcctactataaaccgcgaatctgaaaaaacaaaacgaatacta
gagaagcttaaagaaatggaatttaaaggatataaatacgaaggtgctgaggggtctttg
aaacttctgatacagaaagtgcttggtatgtacaaaccatcatttaagcttatagaattt
aaagtcattgtaaatgaaccgtctgttgatgatgtaaattcatcagctcttataaaaata
gaagtggatggacaggaggaaattactgccgcagaaggtgatggacctgtaaatgctctt
gacaacgcagttagaaaggcgttggagagattttatcctgaagtaaaagagatgaagctt
actgactataaagtaagggtgttagactccaactcagctacagcagcaaaagtaagagta
ataatagaatcatcagatggaaatgaagtgtggagcacaattggcgtatctacagatata
atcgatgccagttggatagcacttgtggattcaatagagtacaaactaaataaaatataa
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