KEGG   Thermochromatium tepidum: E6P07_07395
Entry
E6P07_07395       CDS       T06573                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
ttp  Thermochromatium tepidum
Pathway
ttp00860  Porphyrin metabolism
ttp01100  Metabolic pathways
ttp01110  Biosynthesis of secondary metabolites
ttp01120  Microbial metabolism in diverse environments
ttp01240  Biosynthesis of cofactors
Module
ttp_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:ttp00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    E6P07_07395 (cobA)
Enzymes [BR:ttp01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     E6P07_07395 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     E6P07_07395 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     E6P07_07395 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Other DBs
NCBI-ProteinID: QGU32820
UniProt: A0A6I6EF55
LinkDB
Position
complement(1616884..1618305)
AA seq 473 aa
MDLLPIFLDMQGRPCLVVGGGATAARKVSNLLRAGASVTLVAPELCEALARQVASGALRH
EARRFAPTDISGQRLVIAATDDRAVNRQIAQLAKAADIPVNVVDDPDACTFVLPSIVDRS
PVTIAVSSGKTSPVLARLLRTRLEALIPAGYGRLAELSGRYRERVKARFSEQRDRRRFWD
RVLQGAVAERIFAGQFQEAEAIIEQELAPDALERDMGEVYLVGAGPGDPDLISFRALRLM
QQADVVVYDRLVAAPILNMTRRDAQRIYVGKERNHHAMRQEEINRLLADLAKDGHRVLRL
KGGDPFIFGRGGEEIDTLAAEGVPFQVIPGITAASGCAAYAGIPLTHRDYAQSVTFVTGH
LKDGTIDLNWPALAQPNQTVVFYMGLVGLPVIVERLMAHGVPPEMPIALVQQGTTHLQRV
YTGTLATIRAIVEADPPSPPTLLIVGEVVKLRDKLNWYSPPDEPVQGATTSIV
NT seq 1422 nt   +upstreamnt  +downstreamnt
atggatctactgcccatctttctcgacatgcaaggccgcccatgtctggtggtcggcggc
ggcgccacggcggcgcgcaaggtctccaatctgctgcgcgcaggtgcgtccgtcaccctc
gtcgcgcccgaattgtgtgaggcgctggcgcgccaggtcgcctctggtgccttgcggcac
gaggcgcgccgtttcgcgcctacggacatctccggtcagcgactcgtcatcgccgccact
gatgaccgtgcggtcaatcgacagatcgcgcagctcgccaaggccgccgacatcccggtc
aatgtcgtcgacgacccggatgcctgtaccttcgtgttgccctcgatcgtcgaccgctcg
ccggtgacgattgccgtctccagcggtaagacctcaccggtgctggcacgccttttgcgg
acgcggctcgaggccctgatccctgccggctatgggcggctggccgagttgagcgggcgc
tatcgcgagcgggtcaaggcgcgcttcagcgaacagcgcgacagacgcagattctgggat
cgggtgctgcaaggggcggtcgccgagcggattttcgccgggcagtttcaggaggccgag
gccatcatcgagcaagagttggcgccggatgcactcgagcgcgatatgggtgaggtctat
ctcgtcggtgccggtccgggcgacccggatctcatcagtttccgcgccctgaggctgatg
cagcaggccgatgtcgtcgtgtatgatcggctcgtggccgcacccattctcaatatgacg
cgccgcgacgcgcagcggatctatgtcggcaaggagcgcaaccatcacgccatgcgccaa
gaagagatcaaccggctgctcgccgacttggccaaggacggccatcgggtgcttcggctc
aaggggggggatcccttcatcttcgggcgcggcggtgaggagatcgacaccctggcggcc
gagggcgtgccctttcaggtcattccagggatcacggccgcctcgggctgcgcggcctat
gcaggtatcccgctgacccatcgcgactatgcccagtccgtgaccttcgtcaccgggcac
ctgaaggacggcaccatcgacctgaactggccggcgctcgctcaaccgaaccagaccgtc
gtcttttatatgggcctcgtgggtctgccggtcatcgtcgagcggctcatggcgcacggt
gtgcctcccgagatgcccatcgccctggtccagcagggcacgacccatctgcagcgggtc
tataccggcaccctagcgaccatccgcgcgatcgtcgaggccgatccgccttcgccgccg
acgctcttgatcgttggcgaggtggtcaagttacgcgataagctgaactggtacagtccg
ccggatgagcctgtgcagggggcgacgacctcgatcgtatga

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