Thunnus thynnus (Atlantic bluefin tuna): 137174339
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Entry
137174339 CDS
T11154
Symbol
zgc:158659
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00562
Inositol phosphate metabolism
tty01100
Metabolic pathways
tty04012
ErbB signaling pathway
tty04068
FoxO signaling pathway
tty04070
Phosphatidylinositol signaling system
tty04081
Hormone signaling
tty04140
Autophagy - animal
tty04150
mTOR signaling pathway
tty04210
Apoptosis
tty04218
Cellular senescence
tty04370
VEGF signaling pathway
tty04510
Focal adhesion
tty04620
Toll-like receptor signaling pathway
tty04625
C-type lectin receptor signaling pathway
tty04810
Regulation of actin cytoskeleton
tty04910
Insulin signaling pathway
tty04914
Progesterone-mediated oocyte maturation
tty05100
Bacterial invasion of epithelial cells
tty05132
Salmonella infection
tty05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
137174339 (zgc:158659)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
137174339 (zgc:158659)
04370 VEGF signaling pathway
137174339 (zgc:158659)
04068 FoxO signaling pathway
137174339 (zgc:158659)
04070 Phosphatidylinositol signaling system
137174339 (zgc:158659)
04150 mTOR signaling pathway
137174339 (zgc:158659)
09133 Signaling molecules and interaction
04081 Hormone signaling
137174339 (zgc:158659)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
137174339 (zgc:158659)
09143 Cell growth and death
04210 Apoptosis
137174339 (zgc:158659)
04218 Cellular senescence
137174339 (zgc:158659)
09144 Cellular community - eukaryotes
04510 Focal adhesion
137174339 (zgc:158659)
09142 Cell motility
04810 Regulation of actin cytoskeleton
137174339 (zgc:158659)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
137174339 (zgc:158659)
04625 C-type lectin receptor signaling pathway
137174339 (zgc:158659)
09152 Endocrine system
04910 Insulin signaling pathway
137174339 (zgc:158659)
04914 Progesterone-mediated oocyte maturation
137174339 (zgc:158659)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
137174339 (zgc:158659)
09171 Infectious disease: bacterial
05132 Salmonella infection
137174339 (zgc:158659)
05100 Bacterial invasion of epithelial cells
137174339 (zgc:158659)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tty04131
]
137174339 (zgc:158659)
Enzymes [BR:
tty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
137174339 (zgc:158659)
Membrane trafficking [BR:
tty04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
137174339 (zgc:158659)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Motif
Other DBs
NCBI-GeneID:
137174339
NCBI-ProteinID:
XP_067435666
LinkDB
All DBs
Position
22:complement(26780277..26799466)
Genome browser
AA seq
1070 aa
AA seq
DB search
MAPRPSSGELWGLHLMPPRILVDCCLPNGMMVSLECLRETPLISIKQQLFTEARKYPLYH
LLQEESSYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEKILNREIGFA
IGMPVCEFEMLKDPEVQDFRRSILSVCREAMEEREGGGAHSQALYVYPPNVESSAQLPQH
IYSKLDKGRLIVTIWVIVSPSNSKQKYTLKVSHDSLPEQLIAESIRKKSRSMHLSPQQLR
LCVQEYQGQYILKVCGCDEYLLEKYPLSQYKYIRSCIIVGRLPHLMLVSKDSLYSQLPAS
GFVTPSYSRRTPQPSPCPGGGDGSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRT
GIYHGGEPLCDNVNTQRVPCSNPRWNEWLTYDIYLADLPRSARLCLSICSVKGRKGAKEE
HCPLAWGNVNLFDYQDILVSGKVALSLWPVPHGLEDLLNPIGVAGSNPNKETPCVELEFS
WFNQTVVFPDEQQIEEHANWTISRELGYNYCHGLSSRLACDSSVSAADGEQLRSLCSKDP
LYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEASQMYCLLKEWPLMEPESAL
ELLDCNFPDPMVREFALRCLVQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALT
NQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTL
KQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPL
WLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVKHSFTIMQIQCKGGLKGALQFNSNTLHHWIKDKNRGEAYDRAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGVQESTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDI
AYLRKTLALEKSQQEALEYFTKQMNDAHHGGWSTKMDWIFHTIRHMPNEH
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggcgcccaggccgtcatcaggggaactgtgggggctccacctgatgcccccccgcatc
ctggtggactgttgcctccccaacgggatgatggtgagtctggagtgtcttagagaaact
cctctcatcagcatcaaacagcagctcttcacggaggccaggaagtacccactgtatcac
ctgctgcaggaggagtcgagttacatctttgtgggtgtgactcaggaggcagagagggag
gagttttatgacgagacaaggcggctgtgcgacctccgactgtttcacccaatcctgaag
gtcattgagccgctgggcaaccgggaagaaaagatcctgaaccgagagatagggtttgcc
attgggatgccagtctgtgagtttgagatgttgaaggatccagaggttcaggacttccgc
cgctctatactgagcgtgtgcagagaggccatggaggagagggaggggggtggggcccac
agccaagcactctacgtttacccccccaatgtggaatccagtgcccaactcccacagcac
atctacagcaagctagacaaagggaggttgattgtgactatctgggtgatcgtgtctccg
tccaactccaaacagaaatacacactgaaggtgagtcatgacagtctacctgagcagctg
atagcagagtccatcaggaagaaaagccgatccatgcacctttcacctcagcagctccgc
ctctgtgtccaggagtaccagggacagtacatcctgaaggtgtgtggctgtgatgagtac
ctgttggagaagtatcctctcagtcagtacaagtacatccgctcctgtatcattgtgggt
cgtcttcctcacctgatgcttgtctctaaagatagcctctactctcagctacctgcctct
ggcttcgtcacaccttcatacagtcgccggactcctcagccatctccgtgtccaggaggg
ggtgatggttctcctcctcgctctctgtgggcctttaacactctgctgagggtccgactg
ctctgtgccacgtacgtcaacgtcaacatcagagacattgacaagatctatgtgaggaca
ggtatttatcacggtggagagccgctttgtgacaacgtcaacacacaaagagtcccctgc
tccaaccccaggtggaacgagtggctgacctacgacatctacctggcggacctccctcgc
tcagccagactctgcctttccatctgctctgtgaagggaaggaagggagccaaggaggag
cactgtcctctagcctgggggaatgtgaacctctttgactatcaggacattttggtttcg
ggtaaagttgccctcagtctgtggcccgtccctcatggcctggaggacttactcaatccc
attggggtcgctggttcaaatcccaacaaggagactccctgtgttgagctggagttctcc
tggtttaatcagacggtggtgtttcctgatgagcagcagatagaagaacacgccaactgg
accatcagccgagagcttggctacaactactgccacggattgagcagtcgtctggcgtgt
gacagcagtgtttcagcagcagatggggagcaacttcggtctctctgctccaaagatcct
ctctatgagctctctgagcaagagaaggacttcctctggagacacagacattactgtgta
aacatcccagaatctcttccaaagctccttctgtctgttaaatggaactccagagacgaa
gcgtcacagatgtactgtctgctgaaggagtggcctctgatggagcccgagtcggctctg
gagttgttggactgtaactttcctgatccgatggtcagagagtttgcgctgcgctgtttg
gttcaaggtctgacagacgacaagctgtcgcagtacctgttgcagctcgtacaggtgtta
aagtacgagatgtacctggacaatcctctggctcgtttcctgatcaagaaagctctgacc
aatcaaaggataggacacttcttcttctggcatctcaagtcagagatgcacaacaagaca
gtgtcccgacgctttggtctgctgctggaagctttctgcagagcctgtggcatgtacctg
aaacacctgaacagacaggtggaggccatggataaactggtgaacctgacagacacactc
aaacaagagaagaaggacgagacacagaaaactcagatgaagttcctggttgaacacatg
tctcgtccagattacatggaggctctgcagggattcgtctctcctctgaaccctgttcac
cagctgggaaacctcaggctggaggagtgcaggatcatgtcgtcagcgaagcgccccctg
tggttgaactgggaaaaccccgacatcatgtccgagctgctcttcaccaacaacgaaatc
atcttcaaaaacggagacgacctgcgtcaggacatgctgactctgcagatcattaagatc
atggagaacatctggcagaaccagggcctggacctgcgcatgctgccgtacggctgcctg
tccatcggggactgtgtgggtctgatcgaggtggtgaagcacagtttcaccatcatgcag
attcagtgtaaaggaggcctgaagggggcgctgcagttcaactccaacaccctgcaccac
tggatcaaagacaagaaccggggagaggcgtatgaccgggccatcgacctgttcaccagg
tcgtgtgcaggttactgcgtagcaacattcattctgggaattggtgaccgacacaactcc
aacatcatggtgaaggagaacggacagctgttccacatcgacttcggtcacttcctggat
cacaagaagaagaagtttggttacaagcgggagcgagttcccttcgtgctgacgcaggac
ttcctcatcgtcatcagtaaaggagtccaggagtccaccaagaccaaagagtttgagagg
ttccaggagatgtgctataaagcttacctggccatccggcagcacgccagcctcttcatc
aacctgttctccctcctgctcggctgcgggatgcccgaactgcagagcttcgacgacatc
gcctacctgaggaagaccctggctctggagaagagccagcaggaggcgctggagtatttc
accaaacagatgaacgacgctcatcatggaggctggagcaccaagatggactggatcttc
cacaccatcagacacatgcctaacgagcattaa
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