Thunnus thynnus (Atlantic bluefin tuna): 137183482
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Entry
137183482 CDS
T11154
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tty01001
]
137183482 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tty04131
]
137183482 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tty04147
]
137183482 (lrrk2)
Enzymes [BR:
tty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
137183482 (lrrk2)
Protein kinases [BR:
tty01001
]
Serine/threonine kinases: TKL group
LRRK family
137183482 (lrrk2)
Membrane trafficking [BR:
tty04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
137183482 (lrrk2)
Exosome [BR:
tty04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
137183482 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
TFCD_C
LRR_13
PduV-EutP
Ank_2
Ank_3
LRR_9
T2SSE
AAA_22
Arf
nSTAND3
LRR_NXF1-5
Beta-prop_EML_2
NACHT
Septin
AAA_16
cobW
G-alpha
AAA_7
Ank_5
Gtr1_RagA
MMR_HSR1
Viral_helicase1
ABC_tran
Ank_4
TniB
DLIC
AAA_29
Dmrt1
LRR_EndoS
MobB
TsaE
GTP_EFTU
LRR_6
Motif
Other DBs
NCBI-GeneID:
137183482
NCBI-ProteinID:
XP_067446686
LinkDB
All DBs
Position
5:28739245..28777206
Genome browser
AA seq
2543 aa
AA seq
DB search
MVNKEELEERLKKLLVRLKTPQEDRQLCTLIQIIQDLLFLAHTDCAAELFEDKDVHSPLM
VVLSSYISSRGVQQVGWSLLCRLIEICPSTLDQLTRPLQAAKDWEVLGVHQQILKVLSQY
STDCRVTMVGLRALALLLRSDMIRLLVLEEEDDVFGLVVQAMKTFPTSEEVQLQGCGALQ
FLLERVSDDHLVEFVENQDHVVVLAALQSFPDSPELLLQAMKVLLPLACPGSNVEMLMSG
GARCYSVLIAAMDAFPEVEELQETACCLFKRFTSESYYNILVLNGVQRVAVRACQTFPDN
AALQAAALSCLADLTATIVQNKAVAEQGMEEGEEEENRGKEEVEDMGLGWMEACCTALDL
HAAEPAVQEAASWAIHNLLLHGAGVNHSEEEQDERTPVHRQLMAAMLLHSSSPRVFKAAT
CAIATLITHNGKMRSLLLSSGLHVNIVEMMKRHSTSDEVSISACKLLKLLFQGRTASLDE
LNMAMSQILSTMKIHNFQPEVQLEALQASLVFLCPDRSLREHGVSVADPDMADVSLKVLK
NQCVVEGAHTLYLEVLNRFISSSTIQICGLRVLSALADCSGAVDLLCQQGAIDTVLHTLQ
MFPQEREIHYWGLTLLNYLVSKKKLSRMIVPVLASVLVTSLIQYREDSEMLLKCFQVALR
MLDACSGAAAELQREDFDRQIFQHLREETPDHSNNQLRKSVCLALSKMWCNSELHYSMLE
KACKDGDTTMAECLIELGADINRKTKTESLIYQVCEKGGPLDLVELLLSRGAHEQHLRRA
LAVSVKRGDGPTVIQLLGRLGLDLNNSALCLGGFRLGRLDATWLSPLLAERGRTFSLRYN
NSKGMSLARYIQSFQRTKSAGGPPRSLGDPCLTSGYISDESDDSSFSFISMDDSLFVNDD
MESDGSDSLTGALSAKPHNNSTEELRGSSFKRKGRRRHASAESGQTESEHTEPVHRRYGR
TGSSQKLLVSGENSAGLPKERERIRLLDLSGNELDSLSCLMDDGFVQQQLGHLLRLDLSH
NSLLEFPSALCQNMKSLTRLDLQGNQLQSLPAELLALPSLSTLNVSRNCVGPLLIFDPAV
TCPSLRQLNLSFNKITTFPHELGRAMDQLEELFMEGNSITELCTPLYLPEIKLLDVSKNS
VENISPEFLTGCPKLETFNASTNKICSLSYLPSKITTLKLANNSFTYVSEAILDLPNLRS
VDMRTNSIAVLPGPGFWASSNLRELMFSQNCISTLDLSGPIYKWVRLEKLHLSVNQLTEI
PPQIGLLEGLTSLDVSRNGGLRSFPDEMGKLGRLWDLPLDGLKLQLDLKLIGSKTKDIVR
FLQQRLKKAVPYYRMKLIVVGNTGSGKTTLIQQLMKLKRSQLNSKRTAVGIDVRDWTIRE
RDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNLSKGASQVDALKPWLFNIKAVA
PLSPVILVGTHTDVSEELQLQACLTKIREELLNHQGFPAIRDYHMVSVCEDSDAMTKLRK
AIAREVTSFKIQGQPVMGQLVPDSYVELERRVLQERTRVPPEFPVLRHQELLQLIQESQL
QLEEAELSHAVHFLSEAGVLLHFDDPALQLQELYFIEPQWLCNIISQKLTLKSCGFWEHP
KGVVQRSVVEKFLFETKCFPKSHLTQFFKLLEKFQIALPFGEDQLLVPSSLPKHRPVIEL
PHCENSEVIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGREKVVRPNRIYWRRGVYLSW
SPDAYCLVEAASVEENPSCFVRITVPSSRKGRVLLGQVVDHIDSLLEEWFPGLLNTDMHG
SGEALLKKWALYSFEDGQEWKKILLEDLFTYFDNDFLLVNSEDPRCTLPISQIAPDLVLS
DQPGGTILDSEELEVDLSKENQLGGGGFGTVYRGFYKNEEVAVKIFNKHASELYIYRLLR
QELAVLGRLHHPSLVGLLAAGSAPQVLVMELALRGSLDSLFEHENGSLNRKLQHRIALHV
ADGLRYLHAAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQYCCSMGVRSSEGTPGF
RAPEVARGNVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEVAVQGKLPDPVKH
YGCSPWPGFQALMKDCLRERPQDRPTSAQVFDRLNSGEMLCLMRELVVTRAFNTDCLTVS
SGSSDGPSSSHKAWLGGGSITQRIGSITAVDLDTNTVTTQEIDTSPVLCLVTVQIPNEAH
DWLVAGTQSGSLVVISTLDRSTWHHLQSVTDAVTSLYFHVHPRRTQRKNYLLVGTADGIL
TIYEDSVLKQENGQPVKTLTVGNVNTPVMCLGQSMHSLDSRSVWAGCGTKILSFTADYDV
SKTIDTRPNLIFQQQRSLGGEACVSRMVVDQYVYLSKAGTATIEVWDKRSERMVDCIDCA
QIIRHDSGCRGRQGSEAELPTEAAPSWARVKALLVQSAATLWIGTRGGHLLLLELSKHQT
LQVIAPRCDSIRCIASALIETLNWKNVVLVLGRRLPQDKNHFDEESVLMVWNSTLPMEVK
DLNKHCEKREQIAAQMREQLHHS
NT seq
7632 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaggaggaattggaagaaaggttgaagaaacttctggtgaggctgaaaacc
cctcaggaagacagacaactgtgcactctgattcaaatcatccaggacctgcttttcctg
gcgcacacagactgtgcagctgaactgtttgaagacaaagatgtccacagccccctcatg
gtggtgctgtcatcctacatcagcagtagaggagtccagcaggtgggctggtcgctgctg
tgtcggctgattgaaatatgccccagtacgctggaccagctgaccagacctttacaagcc
gcaaaggactgggaggtactgggagtgcaccagcagattctgaaggttctgtctcagtac
agcacggactgcagagtgaccatggttggactccgagccctggctctcctgctcagatca
gacatgattcgtctgctggtgctggaagaggaggacgatgtgtttggcctggtggtgcag
gcgatgaagactttccctaccagtgaagaagttcagctccaaggctgtggagctctgcag
ttcctcctggagagagtgagtgacgaccaccttgtggagtttgtggagaaccaggaccat
gttgtggttctggcggctctccagagtttcccggacagtcccgagctgctcctgcaggcc
atgaaagtgctgctcccactggcttgtcctggcagtaacgtggagatgttgatgtctgga
ggcgctcggtgctacagcgtgctcatcgcggccatggacgccttcccggaggtggaggag
ctgcaggaaacggcctgctgcctgttcaagaggtttacatcagagagctactacaacatc
ctggtgctgaacggcgtccagagggtggcggtgagggcgtgtcagacgttccccgacaac
gccgcgctgcaagccgccgctctgtcctgcctggctgacctcactgcaaccatagtgcag
aacaaagcagtggccgagcagggcatggaggaaggagaggaggaggagaacaggggtaaa
gaggaggtggaggacatgggcctcggctggatggaggcctgctgcacagcactggatctc
cacgctgctgagccagcagttcaggaagctgcaagctgggccattcacaatctgttactg
cacggagctggagtcaaccactcagaggaggagcaggatgagaggactcctgttcacaga
cagttaatggcagccatgttgctccactcctcctctcccagagtgtttaaagctgctact
tgtgccatcgctacactcatcacacacaacggtaaaatgcgttccctgctgctgtccagt
ggcctccacgtcaacatagtggagatgatgaagagacattcgacctcagatgaagtttct
atcagcgcctgcaaactgctcaagctcctcttccagggaaggacggccagtctggatgag
ctgaacatggccatgagccagatcctcagcaccatgaagatccataacttccagccggag
gtgcagctggaggcgctgcaagccagcctggtcttcctctgcccagacaggagtttacga
gagcatggcgtctcggtggccgaccccgacatggccgacgtgtcgctgaaggtcttgaag
aaccagtgtgtggtggagggagctcacaccctctacctggaggttctcaacaggttcatc
agcagctcgaccatccagatttgtggtttgagggtgctgtctgcgctggctgactgctcc
ggtgcagtggacctgctctgccagcagggggcgatagacacagtgctgcatacactacag
atgttcccacaggaacgagagatacactactggggtctgaccctgctcaactacctcgta
tccaagaagaagctgtcgaggatgatcgtacctgttctcgcctccgttctagtcacgtca
ctcatccagtacagagaagactctgagatgctcctgaagtgttttcaggtggctttgagg
atgctggacgcctgttcaggagcagctgctgaactgcagagagaagactttgacaggcag
atcttccagcacctcagagaggagactcctgaccacagcaacaaccagctgaggaagtcg
gtgtgcttggctctgtctaaaatgtggtgcaactctgagttacactacagcatgctggaa
aaggcctgcaaggacggagacaccacgatggccgagtgtctgatcgagctcggcgctgac
attaacaggaagacaaaaacagaatctctcatctaccaggtatgtgagaaaggaggacca
ctagatctggtcgagctcctgctcagccgaggcgcccacgagcagcacctccgcagggct
ctggctgtgagcgtgaagcgaggcgacggacctacggtcattcagctgctgggccgtctg
ggtctggacctcaacaacagcgccctctgtctggggggctttcggctgggccgcctcgat
gccacttggctcagccccctgctggctgaaagaggcagaacatttagtctccgttacaac
aacagtaaaggtatgagtttggccagatacattcagtctttccagaggaccaagagtgca
ggtggtcctcccaggtctctaggtgacccatgtctgacctctggctacatttctgacgag
agtgacgactccagcttcagcttcatctccatggacgacagcctgtttgtcaacgacgac
atggagagtgacgggagtgattcactgaccggagctctgtctgcgaagccccataataac
tccacagaggagctgaggggcagctccttcaaaaggaagggacgtcgcagacatgccagt
gcggagagcggtcaaactgagagtgaacacactgagcctgttcacaggagatatggaaga
actggctccagccaaaaattgctggtctctggtgagaactctgctggtctgcccaaagag
agagagaggatccgcctgctggacctgtcgggaaacgaactggactctctgtcctgtctg
atggacgacggcttcgtccagcagcagctgggccatctcctccgcctggatctgagccac
aacagcctgctggagtttccctcggcgctctgtcagaacatgaagagtctgactcgactg
gacctgcagggcaaccagctccagtcgctgccggccgagctgctggcccttccctcgctg
agcacgctgaacgtctctcgcaactgtgtcggaccactactgatctttgaccccgctgtg
acctgcccgtcgctgcggcagctcaacctgtcttttaacaaaatcaccacattcccccat
gagctgggccgggccatggatcaactagaggagctgtttatggaaggtaacagtataact
gagctttgcacacctctttatctgccggagatcaagctgcttgatgtgagcaagaacagc
gtggagaacatttctccagaattcctgaccggttgccccaaactggaaactttcaatgca
tccacgaataaaatctgttctctgtcatatctgccatccaagatcacgacacttaaactg
gccaacaacagcttcacttacgtttcagaagctatactcgatctcccaaacttgcgatca
gtagacatgagaaccaacagcattgcggttctacctggacctggtttctgggcgtccagc
aacctgagagagctgatgttcagtcagaactgtatcagcaccctggatctgagtggacca
atctacaaatgggtcagactggagaaactccacctgagtgtcaaccaactcactgagatc
cctccacagatcggtctgttggagggcctgacctccctggatgtgagtcgtaatggtgga
cttcgatctttccctgatgagatggggaagctggggagactgtgggacctgccgctggac
ggtcttaaactccagctggacctcaaactaattggcagcaagactaaagacattgtgagg
ttcctgcagcagcggctgaagaaagcagtgccctactaccggatgaagctcatcgtggtg
gggaatacgggcagcgggaagaccaccctgatccagcagctgatgaaactcaaacgctcc
cagctgaactccaagcggaccgccgtcggtattgacgtgcgggactggaccatcagggaa
cgggacaagaagaaaatggtgctgaacgtctgggacttctcaggtggagaagagttcagt
ggctctcaccctcacttcctgacttccagagctctctacctggtggtgtacaacctgagt
aaaggagccagtcaggtggatgccctcaaaccctggctcttcaacatcaaagcggtagct
ccgctctccccggtcatcctggtgggaacccacacagatgtgagcgaggagctgcagctg
caggcctgtctgaccaagatcagagaggagctgttgaaccaccagggcttcccggccatc
agggactaccacatggtctccgtctgcgaggactctgacgccatgaccaagctccgcaag
gccatcgccagggaggttaccagcttcaagatccagggccagcctgtgatgggtcagctg
gtaccagatagctacgtggagctggaacgccgagttctccaggagaggaccagagttcct
ccagagttccccgtcctcaggcaccaggagctgctgcagctcatccaggagagtcagctg
cagctggaggaagctgagctgtcccacgccgtccacttcctcagtgaagccggggtttta
ctgcactttgatgatcctgcacttcagctccaagagctctactttatcgagccacagtgg
ctgtgcaacataatctctcagaaactgacattaaagagctgtggcttctgggagcatcct
aaaggagttgttcagcgctcagtggtggaaaagttcctgtttgagaccaaatgtttcccc
aagagccaccttacgcagttcttcaaactgttggagaagtttcagatcgctctacccttt
ggggaggaccagctgctggtacccagcagtttgcccaaacacagaccggtaatagagctg
cctcactgtgagaactcagaggtgatcgtgcgtctgtacgagatgccctacttccccatg
gattactggtctcgccagatcagccgccttctggaggtctcgtcctatctgctttgtgga
cgagagaaagtagttcgacccaaccggatctactggaggagaggcgtgtacctgagctgg
tcacctgatgcctactgtctggtggaggccgcctccgtggaggaaaacccctcttgcttc
gtcaggataactgtaccttcttcaagaaaaggccgggtgttgctgggtcaggtggtggat
cacatcgactccctgctggaggaatggtttcccggccttcttaataccgacatgcacggc
agtggagaggccctgctgaagaagtgggctctctacagctttgaagacgggcaggagtgg
aaaaagatactgctagaggatctctttacctattttgacaacgactttctgctggtgaac
tcagaggacccgcgctgcacacttcccatctctcagatcgcccctgacttggtactgagt
gaccagcctggaggaacaatattggacagtgaggagctggaggtggacctatctaaagag
aaccaactggggggcggtggctttggaactgtctatcgaggcttctacaaaaatgaagaa
gtggctgtaaagatattcaacaagcatgcatctgagctttacatctacaggctcctcaga
caggagctggcggtgttgggtcgtctccaccaccccagcctggttggtctgctggcagcc
ggctcagctccacaggtcctggttatggagctggctctacgaggctccctggactctctc
ttcgaacacgagaacggcagcctcaacaggaagctccaacacaggatcgccctgcacgtg
gccgacggactcaggtatcttcacgcagccatgatcatctaccgcgatctgaagccccac
aatgtcctcctgttcaacctgaagaccgactctgagatcatcgccaagatcacagactac
ggcatcgctcagtactgctgcagcatgggagtgaggagctcagagggcacgccaggtttc
cgggctccagaggttgcgcggggtaatgtgatctacaaccagcaggctgatgtgttttcc
ttcggcctgcttctctacgacctcctgacctgcggcgagcgcatctctgacggcatgaag
ttccccagtgagtttgatgaggtcgccgtgcagggaaagctgccagacccggtaaaacac
tacggctgctcaccttggccgggcttccaggcgctgatgaaggactgtctgagggaaaga
cctcaggatcgacccacctctgctcaggtgtttgacaggctgaattcaggagagatgttg
tgtctgatgagggagctggtggttaccagagcgttcaacactgactgcttaacggtgagc
tccggtagcagcgacggcccttcatccagccacaaagcctggctgggaggaggcagcatc
acccagaggattggctccatcacagctgtggacctggacaccaacacagtcactacacag
gagattgacaccagtcccgtcctgtgtcttgtgaccgtccaaatcccgaacgaggcacat
gattggctggtggcaggcacccagtccggctccttagtggtgatcagcactctggacagg
tcgacttggcaccacctgcagagtgtcaccgacgctgtcacctcactgtacttccatgta
catcctcgccgcacccaaagaaagaattatttgctggttggaacagcagatgggattctc
actatttatgaggactctgtactgaagcaggagaacggccaaccagtcaaaactctcact
gtgggcaacgtcaacacacctgtgatgtgtcttggccagtcgatgcactcgcttgacagc
aggtccgtgtgggccggctgtgggaccaagatcctctcctttacggccgactacgacgtc
tccaagaccatcgacacgagacccaacctcatcttccagcagcagcgctcactcggcggg
gaggcgtgtgtgtctcgtatggtcgtggatcaatacgtatacctgagcaaagccggcaca
gcaaccattgaggtttgggacaagaggagtgagagaatggtggactgcatcgactgcgct
cagataatcagacatgactctggctgcagaggcaggcagggcagtgaggcggagctgccc
accgaggcggctccctcctgggccagagtgaaggccctgctggtgcagagcgctgcaact
ctctggatcggcactagagggggccatctgctgctgctggagctctccaaacaccagaca
ctgcaggtcatcgcccctcgctgcgattccatccgctgcatcgcctctgcactcatagaa
acactaaattggaagaatgtggtgctggttctgggtagaagactcccacaagacaagaat
cactttgacgaggagtcggtgctgatggtgtggaacagcacgctgccgatggaggtcaaa
gacctgaataaacactgcgagaagagagagcagatcgcagcccagatgagagagcagctc
catcacagctga
DBGET
integrated database retrieval system
