Thunnus thynnus (Atlantic bluefin tuna): 137183597
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Entry
137183597 CDS
T11154
Symbol
hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00140
Steroid hormone biosynthesis
tty01100
Metabolic pathways
Module
tty_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
137183597 (hsd17b2)
Enzymes [BR:
tty01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
137183597 (hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
137183597 (hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
Motif
Other DBs
NCBI-GeneID:
137183597
NCBI-ProteinID:
XP_067446866
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Position
5:32134756..32148265
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AA seq
376 aa
AA seq
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MDACFCVAAAAAFTFTVVWTLKQGCDAGYWSVAFGALGASLYFTAPLVYCGVALLCCSLA
LVCVTARTAELLPLQGRAVLVTGCDSGFGHALAKRLSKMGVQVFAGVLDVNGAGAQQLRD
QVCENLQVLQLDVTDSSQIETTHLHIRAQVGDSGLWGLVNNAGILHCPLDAELHPVTLYR
RVMDVNFLSAVKMCQVFLPLLRRSRGRIVNVASMAAEVPMPMFAAYGASKAALSVFSKVM
RLELSVWGVRVALIQPSGFRTNIFGNSDTISRYRDEILAGVSSDAREDYGEAYISSLPSS
LTKLSQMSVEDLSPVVDNMCHALLSVQPRPLYTPGKMGWFLPFLHRHLPTTLFDCVIMNL
QKYTDCEPAGLHVNSG
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atggatgcctgtttctgtgttgcagctgcagcagcgttcactttcacggtggtttggacg
ctgaagcagggctgtgatgctggatactggtctgttgcgttcggggcccttggggcctct
ctgtacttcacagctcctctggtgtactgcggggtcgccttactgtgctgcagcctcgct
ctggtgtgtgtgactgcgaggacggccgagctgctgccgctgcagggcagagcggtgctg
gttacaggttgtgattcaggtttcggtcatgcgctggcgaagcggctgagcaagatggga
gtgcaggtgttcgcaggtgtgctggatgtgaacggtgctggagctcagcagctgagagac
caagtatgtgaaaacctgcaggtcctgcagctcgacgtgaccgacagctcccagatagag
acgacacacctgcacatccgcgctcaggtcggagactcaggtttgtggggtttagtgaat
aacgcaggaatccttcactgtcctctggatgcagagctgcatcctgtcacattgtacaga
cgcgtcatggacgtcaacttcctgtctgcggtgaagatgtgtcaggtgttcctgcctctg
ctgcgcaggtccagaggacgcatcgtcaacgtggccagcatggcagctgaggtgccgatg
cccatgttcgctgcttacggagcatcgaaggcggcgctgagtgttttctccaaagtcatg
aggctggagttgtctgtgtggggcgtcagagtggctttaattcagccttcaggcttcaga
acaaatatctttgggaacagtgacaccatcagtcgctaccgagacgagatcctcgcaggt
gtctcctctgatgccagagaggattatggggaggcgtacatctcgtctctccccagcagt
ttgaccaaactgtcccagatgtcagtggaggatctgtctcctgtggtggacaacatgtgt
catgctctgctgtccgtccagcccagacctctgtacacccccggaaagatgggatggttc
cttccatttcttcaccgccaccttcccaccacgctgtttgattgcgtcatcatgaacctc
cagaaatacaccgactgtgagcctgcaggcctccacgtcaactcaggttaa
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