Thunnus thynnus (Atlantic bluefin tuna): 137186407
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Entry
137186407 CDS
T11154
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00280
Valine, leucine and isoleucine degradation
tty00640
Propanoate metabolism
tty00785
Lipoic acid metabolism
tty01100
Metabolic pathways
tty01210
2-Oxocarboxylic acid metabolism
Module
tty_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
137186407 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
137186407 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
137186407 (bckdha)
Enzymes [BR:
tty01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
137186407 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
137186407
NCBI-ProteinID:
XP_067451428
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All DBs
Position
7:complement(28617891..28624691)
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AA seq
440 aa
AA seq
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MNKIYGVCFHAVRQAAGLKASRLLQHRAFRASAVHGQQPFDSSMEKPQFPGASAEYVDHL
EFIQPNVISGIPVYRVMDRQGNIIDPTQDPQLSKETVLNFYQKMTLLNTMDRILYESQRQ
GRISFYMTNYGEEGTHIGSAAALDPNDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDL
GKGRQMPVHYGSKDLNFVTISSPLATQIPQAVGAAYAIKRENTNRAVICYFGEGAASEGD
AHAGFNFSATLECPMIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMMSIRVDGNDVFA
VYNATKEARRRAVAENQPFLIEAMTYRVGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLR
HYMTARNWWSEDDERNWRKQSRKMVMEVFERAERRLKPNPELLFTDVYQEMTPSLTKQRE
SLWRHVQQYKEHYPLDMYDK
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaacaaaatatatggagtctgtttccatgctgttcgtcaagcggcaggtctgaaggca
tcgaggttgcttcaacacagagccttcagagccagtgccgtgcacggacagcagcccttt
gattcgtcgatggaaaagccacagtttcctggagcctcagctgagtatgtggatcacctt
gagttcatccagcccaatgtcatctctgggatcccagtgtaccgggtgatggaccggcaa
ggcaatatcatcgaccccactcaagaccctcagctctccaaagagacagtcttgaacttt
taccagaagatgactctgctgaacacaatggaccgcattctttatgaatctcagagacag
ggtcggatttccttctacatgacaaactatggtgaggaggggacacatatcggtagtgct
gctgctctcgacccaaatgacctggtcttcggtcaatacagagaggctggagtgctgatg
tatcgaggttttcctctggatttgttcatggctcagtgctacgctaatgctgatgacctt
ggaaagggccggcagatgcccgtccactacggctccaaagacctgaactttgtaaccatc
tcttctcccctggccacacaaattcctcaggcggtcggagctgcgtatgcaattaagaga
gaaaacaccaaccgagctgtaatctgttatttcggagagggagcagctagcgaaggcgac
gcccacgctggcttcaacttctctgccaccctcgagtgccctatgatcttcttctgccgt
aacaatggttacgccatctctacccccaccaacgagcagtacagaggagacggcatcgct
gctcgcggtcccggttacggcatgatgtccatccgtgtcgatggtaatgatgtgtttgct
gtgtacaacgctacaaaggaagctcgccgcagggccgtggctgagaaccagcccttcctc
attgaggcgatgacctacagagtcggccaccacagcaccagcgacgacagctcggcttac
cgttcggtggacgaggtgaactactgggacaagcaggaccatcccatctccaggctgaga
cattacatgacagcccgcaactggtggagcgaggacgacgagaggaactggcggaaacaa
tcccgcaagatggtgatggaggtgttcgagagggccgagagacgcctgaaacccaatccc
gagctgctcttcaccgacgtgtaccaggagatgacgcccagcctgaccaagcagagggaa
tccctgtggaggcacgtgcagcagtacaaggagcattacccgcttgatatgtatgataaa
taa
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