Thunnus thynnus (Atlantic bluefin tuna): 137187438
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Entry
137187438 CDS
T11154
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00562
Inositol phosphate metabolism
tty01100
Metabolic pathways
tty04012
ErbB signaling pathway
tty04068
FoxO signaling pathway
tty04070
Phosphatidylinositol signaling system
tty04081
Hormone signaling
tty04140
Autophagy - animal
tty04145
Phagocytosis
tty04150
mTOR signaling pathway
tty04210
Apoptosis
tty04218
Cellular senescence
tty04370
VEGF signaling pathway
tty04510
Focal adhesion
tty04517
IgSF CAM signaling
tty04518
Integrin signaling
tty04620
Toll-like receptor signaling pathway
tty04625
C-type lectin receptor signaling pathway
tty04810
Regulation of actin cytoskeleton
tty04910
Insulin signaling pathway
tty04914
Progesterone-mediated oocyte maturation
tty05100
Bacterial invasion of epithelial cells
tty05132
Salmonella infection
tty05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
137187438 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
137187438 (pik3ca)
04370 VEGF signaling pathway
137187438 (pik3ca)
04068 FoxO signaling pathway
137187438 (pik3ca)
04070 Phosphatidylinositol signaling system
137187438 (pik3ca)
04150 mTOR signaling pathway
137187438 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
137187438 (pik3ca)
04517 IgSF CAM signaling
137187438 (pik3ca)
04518 Integrin signaling
137187438 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
137187438 (pik3ca)
04140 Autophagy - animal
137187438 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
137187438 (pik3ca)
04218 Cellular senescence
137187438 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
137187438 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
137187438 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
137187438 (pik3ca)
04625 C-type lectin receptor signaling pathway
137187438 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
137187438 (pik3ca)
04914 Progesterone-mediated oocyte maturation
137187438 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
137187438 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
137187438 (pik3ca)
05100 Bacterial invasion of epithelial cells
137187438 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tty04131
]
137187438 (pik3ca)
Enzymes [BR:
tty01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
137187438 (pik3ca)
Membrane trafficking [BR:
tty04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
137187438 (pik3ca)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
137187438
NCBI-ProteinID:
XP_067452408
LinkDB
All DBs
Position
8:7554052..7580336
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTQELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTAASYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSPVKYPDMNAVEDHANWTISRELGFNYNLSGQSNRVARDHALTESDIEQLRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDSPLARFLLKKALTN
QKIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNFTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNALHQWLKDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcccaggccgtcctcaggggagctatggggcatccacttgatgcctcccaggatc
ctggtggactgcctgctgcccaacgggatgattctgaccctggagtgtctccgtgaggcc
acgctcatcaccatcaaacacgaactgttcaaggaggccagaaaatatcctctccatcac
ctcctacaggaggagacttcctacatcttcgtcagtgttacgcaggaagcagagcgggag
gagttctatgatgagacccggaggctgtgtgacctcagacttttccagcctttcctcaag
gtcattgaaccagttggcaacagagaggaaaagatccttaacagagagattggttttgcc
attggtatgccagtgtgtgagtttgacctggtgaaggacccggaggttcaggatttcagg
agaaacatcctgaatgtttgtaaagactctgtggagctgagagacgccagcgggccccac
agcagagccctgtatgtttacccacccaatgttgaatccacacaggaactacccaaacac
atctacagcaaactggacaaaggccagattatcgttgtgatttgggtgattgtctctccg
aacaacgacaagcaaaagtacacactgaagatcaaccacgactgtgtgcctgaacaggtg
atcgcagaggccattcgtaagaagacacgcagcatgctgctgtcccccgagcagctaaag
atgtgtgttcaggaataccagggtaaatacatcctcaaagtttgtggctgtgatgagtac
ctgctggaaaagtaccccatcagccagtataagtatatccgtagttgcatcatgctgggc
aggatgcctaacctgatgctaatggctaaggacagcctgtacacccagttgcctacagat
aactttgtcatgccgtcatactcccgccgcatctccacggcagcgtcctatatgaacggc
gaggcagctgccaagtcgctgtggaccatcaatggaactctgcgaatacgaatcctctgt
gccacctatgttaacgtcaatatacgagacatagacaagatttatgtgagaacaggtatt
taccatggaggagaacagatgtgtgacaatgtcaacacacagagagtaccctgctccaac
cccaggtggaacgagtggctgacctatgacatgtacatcccagacatcccccgagccgcc
agactttgcctctccatctgctcagtgaagggcaggaagggagcaaaggaggagcattgt
cccttggcctggggtaatgtcaacttgtttgactacacccacactctggtggctaacaag
atggctctgaacctctggcctgttcctcatggccttgaagacctcctcaaccccatagga
gtcacaggctccaaccccaataaggaaacgccatgtctggagctggaatttgaccacttc
agtagtccagtcaaatacccagatatgaatgctgtagaggatcacgcaaactggaccatc
tcaagagaactggggttcaactacaacctctctggacagagcaatcgtgtggccagagat
cacgccctgacagagagcgacatcgagcagctgagacagctcagtaacagagaccctctt
tcagaaatcactgagcaggagaaagacttcctctggagacacaggcactactgcatgaac
atccctgagatccttcccaagatccttctcgctgtcaaatggaactccagagatgaagta
gcacagatgtattgccttttaaaggaatggccgtccattcgtcctgagcaggccatggaa
ctgttggattgtaattatccagaccccatggtcagacactttgctgtacgatgccttgac
aaatacctgacagatgacaaactgtcacagtacctcatccagcttgtacaggtgttaaaa
tacgagcagtaccttgatagtcccctggcccgtttcctccttaaaaaggccctgaccaat
caaaagataggacatttcttcttctggcatctcaagtcagaaatgcacaacaaaacagtg
agccagaggtttgggttgctgttagaggcttactgcagggcttgtggcatgtacctcaaa
cacttgagcaggcaggtagaggccatggagaagctcattaacctcactgacatcctcaaa
caggagaagaaggatgagacgcagaaggtccagatgcggtttctcgtggaccagatgaaa
agaccggactacatggatgctctgcagaacttcacctctcctctcaaccctgcacaccaa
ctgggaaacctgaggttagatgaatgtaggatcatgtcatcagcgaagaggccgctgtgg
ctgaactgggagaatcctgacatcatgtctgagctgctctttcagaacaatgagatcatc
ttcaaaaatggagacgacttgcggcaggatatgctgactctgcagattattaaaatcatg
gagaacatttggcagaatcagggactggacctacggatgctgccctatggctgtctgtca
ttaggagactgcgtgggtctcatcgaggtggttcgcagctctcacaccatcatgcagatt
cagtgtaaaggcggcttgaagggagccctgcagttcaactccaacgctctgcatcagtgg
ctcaaggacaagaataagggcgagatgtatgatctggctgtggatctgtttacgaggtcg
tgcgctggctactgtgtagctacatttattcttgggataggagacaggcacaacagcaac
attatggtcaaagatgatggacagttgtttcatatagattttggccatttcctggatcat
aagaagaagaaatttggctacaagagagagcgagtgccctttgttctgacgcaagacttc
ctcatcgtcatcagcaaaggttcccaggagtgtgcaaagaccaaagagtttgaaaggttt
caggagatgtgttataaagcctacctggccatccggcagcatgctaacctgttcatcaac
ctgttctccatgatgctgggctccggcatgcctgagctgcagtcatttgatgacatcgcc
tacattaggaagacgctggccctggagaaaactgaacaggaggcgctggactactttatg
aaacagatgaacgatgctcaccatggaggatggaccaccaagatggactggattttccac
acaatcagacagcatgcactaaactga
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