KEGG   Thunnus thynnus (Atlantic bluefin tuna): 137200009
Entry
137200009         CDS       T11154                                 
Symbol
plcb2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
tty  Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty00562  Inositol phosphate metabolism
tty01100  Metabolic pathways
tty04020  Calcium signaling pathway
tty04070  Phosphatidylinositol signaling system
tty04081  Hormone signaling
tty04082  Neuroactive ligand signaling
tty04261  Adrenergic signaling in cardiomyocytes
tty04270  Vascular smooth muscle contraction
tty04310  Wnt signaling pathway
tty04371  Apelin signaling pathway
tty04540  Gap junction
tty04621  NOD-like receptor signaling pathway
tty04912  GnRH signaling pathway
tty04916  Melanogenesis
Module
tty_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:tty00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    137200009 (plcb2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    137200009 (plcb2)
   04371 Apelin signaling pathway
    137200009 (plcb2)
   04020 Calcium signaling pathway
    137200009 (plcb2)
   04070 Phosphatidylinositol signaling system
    137200009 (plcb2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    137200009 (plcb2)
   04081 Hormone signaling
    137200009 (plcb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    137200009 (plcb2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    137200009 (plcb2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    137200009 (plcb2)
   04916 Melanogenesis
    137200009 (plcb2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    137200009 (plcb2)
   04270 Vascular smooth muscle contraction
    137200009 (plcb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tty04131]
    137200009 (plcb2)
Enzymes [BR:tty01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     137200009 (plcb2)
Membrane trafficking [BR:tty04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    137200009 (plcb2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    137200009 (plcb2)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLC-beta_C PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 137200009
NCBI-ProteinID: XP_067470774
LinkDB
Position
16:complement(19657253..19681277)
AA seq 1273 aa
MNKKRYFLDPPEIKDYLVKGERFTRWSEDSTKTDHVTMKMDLKGFYLYWINQSKETTFVD
VATIRDTRTGKYAKLPKHSKVRNVFNLDFPDSNHLAKTLTIVSGPDTVNLTYHNFFASKE
KVTQNWANDILAIAYNAARNNACRQVFLEKIYTRISLQTNKDGKIPVKNIYKMFPADKKR
VESALASAHLPKGKYDTMKPDVFTEAAFKAFLSNLCPRPEIYEIFTSYSTKPTMTKENFT
KFLNEKQRDSRLNEELFPRLRQDQIKALIDKYEPLSANSNRGLISPEGLLCFLMGPETSV
VMQDRLAKCQDMTQPLPHYFIKSSHNTYLTAGQFSGVSSPEMYRQCLLSGCRCLELDCWK
GKPPDEEPIITHGFTMTTEILYKDVIEAIAESAFKTSQYPVILSFENHVDSVKQQEKMAN
YCKTIFGDALLTDPLDKYPLKPGQQIPSPSELMGKILIKNKKGSHEKPSQTKKTSTAASD
QTTATAAPTPDPKTTSQDPANPAAPSTQENQEGDAAVEDNEEQEETEEQDEEKMKTSDEG
TAGQEVTAYEEMSALVNYIQPHKFISFDNARKKNKSYVISSFVETKGEAMISKTAVEFVE
YNKRQMSRIYPKGTRMDSSNYSPQPFWNVGCQMVALNYQTMDFPMQLNMALFEFNGRTGY
LLKHDVLRRSDKKFDPFCDRIDTVVASTLTIKIYSGQFLSDKNVKTGVEVEVIGLPGDPK
KKYRTKWSTTPNAINPVWNEEPFVFEKILLPEMASLRIVVHEENGKFVGHRIIPLDAIQS
GFHHICLRSESNMLLTLPALFVYIEVKDYIPAAFADFTDALFNPTKGTEKTAKTTKESSS
DYISPYELPLVVQTPTEKAKKNEAPATEKASFEPATPVEANEQSLQSPSETSAEEAKEES
TPETPQPAAEPPQTPDTPPVEDVAPDAGNTTSETPRESPKEVPPEKEEPEATPEDKEEPD
TDSSANPEPVSDEKPCTETASTADEVQGEPTAVAEPCPASASPEPAGSDDLSHPPTCSEE
PSTVTTEELTQHKNYLKVIKRQEREMKEAEKKYLKKGEDLIQKYSDSFKAMKKKTSEKKK
EGGGNTSDSSVKTERVQEQKEKMQVELQALWREQSDQLKKRKEQCATERLAKLLEMATER
HTSELKTLESESKENKKKTLSKFSSSQKAKLKKAGSTELLDETSHSDGGSSDYSPQQEAL
IKKQAATLEEIKALTNQLNQEALREHEQKMRSLPAEVREAVNACVGAHFPKLVDQAGDNK
VECVGFYGDVFLG
NT seq 3822 nt   +upstreamnt  +downstreamnt
atgaataagaaaaggtactttctggatcctccagagatcaaagactatctggtcaaagga
gaaagatttaccaggtggtcagaggactcaacgaagactgatcatgtcaccatgaagatg
gatctgaaagggttttatctctactggatcaaccaaagcaaggaaacaacattcgtggat
gttgctaccatcagagataccagaacagggaaatatgcaaaacttcccaaacactcaaag
gtccgcaatgtgttcaacctggacttcccagacagcaaccaccttgccaaaaccctgacc
atcgtctcaggtccagacacagtgaatctgacctatcataacttctttgcatccaaggag
aaagtaacacagaactgggcaaatgacatccttgcaattgcctacaacgctgcaagaaac
aatgcatgcagacaagtcttcctggaaaaaatatacacccggatttctcttcaaaccaac
aaggacggcaagatccctgtgaaaaatatttacaagatgttccctgcggataagaagagg
gtagagagtgccctggcgtcagcacacctccccaaaggaaagtatgacaccatgaagcct
gatgtcttcactgaagctgccttcaaggccttcctgtcaaatctctgccctcgacctgag
atctatgagatcttcacttcttactccaccaaacccaccatgacaaaggagaacttcacc
aagttcctcaatgagaaacagagggactcccgcctcaacgaggagctgtttccacgactg
cggcaggaccagatcaaggctttaatagacaaatatgaacctctctctgctaattctaac
agaggcctgatctctccagaaggccttttatgcttcctgatggggccggagacgtcagta
gtgatgcaggacaggctggcaaagtgtcaggacatgactcagcccttaccccactacttc
atcaagtcctcccacaacacatacctgacagctggtcagttttctggcgtgtcttctccg
gagatgtaccgtcagtgtctgctgtccggctgccggtgtctggagctggactgctggaag
ggaaaacctccagatgaagagcccatcatcacccacggcttcaccatgacgactgagatt
ctctacaaggatgtgattgaggccattgctgagagtgccttcaagacctcacagtaccct
gttatcctctcatttgagaaccacgttgactcggtgaaacagcaggagaagatggcaaac
tactgcaaaaccatatttggtgatgccctgctgacagacccgctggacaaataccctctt
aaaccaggccagcagatccccagcccatctgagctcatgggcaagatccttatcaagaat
aaaaagggcagccatgagaagccaagccagactaagaaaaccagcacagcagccagtgac
cagaccacagccacagctgcacccaccccagacccaaaaaccacttcccaggatcctgct
aacccagcagcacccagcacccaggagaaccaagaaggggacgcagctgtggaggacaac
gaggagcaggaggaaacggaggaacaggatgaggagaaaatgaagacatccgatgagggc
acagctggacaagaagtaacagcgtacgaggaaatgtcagccctggtcaactacatccaa
ccccacaaattcatctcttttgacaatgccagaaagaaaaacaagagttacgtcatctca
tcttttgtggagactaaaggggaggcaatgatttccaagactgctgttgagtttgtcgaa
tacaacaagaggcagatgagtaggatttaccccaaaggaacaagaatggactcatccaat
tacagtccccagccgttttggaacgtaggctgccagatggtggcgctcaactaccagacg
atggatttccccatgcagctgaacatggctctgtttgaattcaacgggagaacgggctac
ctgctcaagcatgatgttctgcgtcgcagtgacaagaagtttgaccctttctgtgacagg
atcgacaccgttgtggcaagcacgctgaccataaagatctattccggccagtttctgtct
gacaagaatgtcaaaacaggggttgaggtggaggtgattgggctgccgggggaccccaag
aagaaatatcgcactaagtggtccaccacacccaacgccattaaccctgtgtggaatgag
gagccttttgtctttgagaagattctgctcccagaaatggcctctttgagaattgtagtc
catgaagaaaacggtaaattcgtggggcacaggatcatccctcttgatgctatccaatca
ggcttccatcacatctgcctgcgcagcgagagcaacatgctgctcactctgcctgctctc
tttgtgtacatcgaggtcaaggactacatccctgctgccttcgcagatttcacagatgcc
ttatttaacccaacaaagggcacagagaagactgcaaagaccacaaaggagtcatcttct
gactacatttctccttatgagctgcctctcgtggtacaaacccccactgagaaggccaag
aaaaatgaagcccctgctacagaaaaggcatcatttgaacctgcaacacccgttgaggcc
aatgaacaatcattgcagtctccatctgaaacaagtgcagaagaagctaaagaagagagc
acaccagagactccacaacctgcagcagagcctcctcaaactcctgatacccctcctgtt
gaagatgtagcaccggatgcaggaaacaccacatctgaaactccccgtgaatctcctaaa
gaagttccccctgagaaggaagagcctgaggcaactcctgaagacaaagaggagccggac
actgactccagtgcaaatcctgagcctgtttcagatgaaaaaccgtgcacagaaactgcc
agcacggctgacgaggttcaaggagagcctactgctgtggctgaaccctgtccagcaagt
gcatctcccgagcctgcaggatcagatgacttatctcacccgccaacatgtagcgaagag
ccttcaactgtgactactgaagaactgacacagcataagaactatctgaaggtcatcaag
cgtcaagagagagagatgaaagaagcagaaaagaaatatctgaaaaaaggagaggatcta
attcagaaatactctgactccttcaaggccatgaagaagaagacctcagagaagaaaaaa
gagggagggggaaacacatctgactccagtgtgaagacggagcgggtgcaggaacagaag
gaaaaaatgcaggttgagctgcaagctttgtggcgggagcagtctgatcagctgaaaaag
aggaaagagcagtgtgccacagagagactggccaaactgctggagatggccacagagaga
cacaccagtgaactgaagactctggagagtgaaagcaaagaaaataagaagaaaacgctc
tcaaaattctcatcctcacagaaagcaaagctgaaaaaggcaggaagtacagagctgttg
gatgagactagtcactctgatggtggatcttcagattacagtcctcagcaagaggctctg
atcaagaagcaggctgctacactggaggagatcaaggcactgactaatcagctcaatcag
gaggccctgagggagcacgagcagaaaatgaggtctctgccagccgaggtgagggaggct
gtcaacgcctgtgtgggggctcacttccccaaacttgtcgaccaggctggggacaataag
gtggaatgtgtgggcttctatggagatgtcttcttgggttag

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