Tenuifilum thalassicum: FHG85_02875
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Entry
FHG85_02875 CDS
T06728
Name
(GenBank) bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
KO
K01798
Alr-MurF fusion protein [EC:
5.1.1.1
6.3.2.10
]
Organism
ttz
Tenuifilum thalassicum
Pathway
ttz00300
Lysine biosynthesis
ttz00470
D-Amino acid metabolism
ttz00550
Peptidoglycan biosynthesis
ttz01100
Metabolic pathways
ttz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ttz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FHG85_02875
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
FHG85_02875
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FHG85_02875
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FHG85_02875
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ttz01011
]
FHG85_02875
Enzymes [BR:
ttz01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.1 Acting on amino acids and derivatives
5.1.1.1 alanine racemase
FHG85_02875
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FHG85_02875
Peptidoglycan biosynthesis and degradation proteins [BR:
ttz01011
]
Precursor biosynthesis
Amino acid ligase
FHG85_02875
Racemase
FHG85_02875
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ala_racemase_N
Ala_racemase_C
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QKG79249
UniProt:
A0A7D3Y371
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All DBs
Position
690633..693101
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AA seq
822 aa
AA seq
DB search
MINLSVTKIAEIVQGEVIGDSNRIVNNVLTDSRIPVSGSRVIFVAINGQNHNGHEFVYEL
YEYRDINVFLVEKDEVNYSLCPEASFVIVDDTLQALQKLAVYHRNRFAYPIIGITGSNGK
TIVKEWLNQLLSDEYQIVRSPRSYNSQVGVPLSVLQMDDHFDLGIFEAGISKPGEMVKLQ
PIIDPSIGIFTNIGMPHQENFDDIDEKVNEKLKLFREVNTLIYCKDHAVIDTIARENTLL
ADNQLLTWGQNPEANIKVRSIKRLESKTEVHVQYKQQEFNLTIPFIDGASYENAMHCVAT
MLLLGYKASDIEERLKRLQPVAMRLELLEGINGCSLINDSYNSDLGSLAIAVDFLMQQKQ
HDKHVVILSDILESGYAPEQLYSKVAQMLEDKGVDLLIGIGPEISRYDYAFDIDADFYTS
THEFLADLKRRELRDSAILIKGSRKFHFEQICSTLERKVHRTILEINLNAISHNLNHYRS
LLNPDVMIMAMVKAFSYGSGSFEIANLLQYHRVDYLGVAYTDEGVALREAGITLPIIVLN
PSFGTYEVMIEFNLEPEIYNFAGLREFISVLNRVGVSSYGIHLKIDSGMHRLGFLPVQVD
ELLDIIKSTNSVRVESIFSHLAASDEPQHDEFTKQQIEIFSSVYDKLSEGLGYKPVKHIL
NTGGIERFPEAQFDMVRLGIGLYGISPTQQDKLMPISTLRSKVIQVKYVQPGETIGYSRR
GVVEKPTTVVTIPVGYADGLSRLLGNGNYRMMLNGKLVPTIGNISMDTTMLDATGVDVKE
GDEVIVFGNEPTIADMAKAMGTIQYEVLTSISQRVKRVYFQE
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgattaatttatcagtcacaaagattgcggagatagttcaaggtgaagtaattggcgat
tctaatcggattgtcaataatgtacttaccgatagtagaattcctgtgtcagggagcagg
gtgatttttgttgctatcaatgggcaaaatcacaatggccatgagtttgtttatgagctt
tatgagtatcgcgatataaatgtttttctggtagaaaaggatgaggtaaattattctctc
tgtcctgaggcctcttttgtcatagttgatgacacacttcaagcactacaaaagttagct
gtttatcatcgaaatagatttgcatatcctattataggcatcaccggaagtaatggtaaa
accatagttaaggagtggctaaatcagctattatccgatgaataccagattgttcgcagc
cctcgtagttataattcacaggtgggggttcccttatcggttctgcagatggatgaccat
ttcgacttgggtatttttgaagcaggtatttctaagccaggagaaatggttaaacttcaa
cctattattgacccatcaatagggatattcacaaacataggaatgcctcatcaagagaat
tttgatgatattgacgaaaaggttaatgaaaagttaaagctattcagagaggtaaacact
ctcatttactgtaaggaccatgcagtaattgataccatagcaagggagaatactcttttg
gctgataatcagctgttaacatgggggcaaaatcctgaagcaaacatcaaagtaagaagc
attaaaagacttgaatctaaaaccgaagtacacgttcaatacaaacagcaggagtttaac
ctgacaattccatttatcgatggtgcatcgtacgaaaatgcgatgcattgcgtggcaacc
atgttgctgttgggttacaaggcttctgatatagaagagcgcctaaagcgcctgcaacct
gttgccatgcgacttgaactgcttgaaggtataaacggatgctctttaattaacgactcc
tacaactccgatttaggctctctagcaattgctgtcgattttttaatgcagcaaaagcag
catgataagcatgtagtaatcctttccgatattcttgaaagcggttatgctcctgagcag
ctctactctaaggtggcgcagatgttagaagataaaggcgttgatttgcttattggtatt
ggccctgaaataagccgatacgattacgcatttgatattgatgccgatttttacacatcg
acacatgaattccttgccgacttgaaacgtagggagttacgcgattctgcaatactgatt
aagggtagcagaaaatttcattttgagcagatatgctctactttagagcgcaaggtacat
cgaaccatactcgaaatcaaccttaatgccatatcacataatcttaaccactaccgcagc
ctgcttaatcctgatgtgatgattatggctatggtaaaggcattctcatacggaagtggt
tcctttgagattgctaatcttttacaatatcatcgtgtcgattaccttggagttgcttat
accgacgaaggtgttgcacttagagaagcaggaattaccttgccaataattgtacttaac
ccttcctttggtacttacgaggtgatgattgagtttaaccttgaacctgaaatatacaac
tttgctggtttaagagagtttatatccgtgctaaatagagtgggggttagctcctatggc
attcacctaaaaattgatagcggaatgcatcggttaggatttttacctgtccaggtagat
gagctcttagatataattaagtcaacaaattcggttcgagtcgagagtatattctcgcat
ctggcagcaagcgatgagccccagcacgatgagtttacaaaacaacagatagagatattt
tcaagtgtatacgataaactttccgaaggccttgggtataaacctgtcaaacatatttta
aatactggtggaattgagcgtttccccgaagctcagttcgatatggttcgtttaggaatc
ggcctatatggcattagtccaacccaacaggataagctaatgcctataagcacgttaagg
agtaaggtgatacaggttaagtacgttcaacctggcgaaacaattggttatagtcgaagg
ggcgtagttgagaaaccaacaacagttgtaaccattccggttggctatgccgatgggctt
tcgcgacttcttggaaatgggaattatagaatgatgcttaatggaaagctcgttcctact
attggtaacattagcatggatactaccatgctcgatgctacaggtgttgatgttaaagag
ggcgacgaagtaatcgtatttggcaatgagcccactattgccgatatggcaaaagcaatg
ggcaccattcaatacgaggtgctaacatcaatatcgcaaagggtgaaaagggtttatttt
caggaatag
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