Tupaia chinensis (Chinese tree shrew): 102473496
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Entry
102473496 CDS
T02978
Symbol
IGF1R
Name
(RefSeq) insulin like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521
EGFR tyrosine kinase inhibitor resistance
tup01522
Endocrine resistance
tup04010
MAPK signaling pathway
tup04014
Ras signaling pathway
tup04015
Rap1 signaling pathway
tup04066
HIF-1 signaling pathway
tup04068
FoxO signaling pathway
tup04081
Hormone signaling
tup04114
Oocyte meiosis
tup04140
Autophagy - animal
tup04144
Endocytosis
tup04150
mTOR signaling pathway
tup04151
PI3K-Akt signaling pathway
tup04152
AMPK signaling pathway
tup04211
Longevity regulating pathway
tup04213
Longevity regulating pathway - multiple species
tup04510
Focal adhesion
tup04520
Adherens junction
tup04550
Signaling pathways regulating pluripotency of stem cells
tup04730
Long-term depression
tup04913
Ovarian steroidogenesis
tup04914
Progesterone-mediated oocyte maturation
tup05200
Pathways in cancer
tup05202
Transcriptional misregulation in cancer
tup05205
Proteoglycans in cancer
tup05214
Glioma
tup05215
Prostate cancer
tup05218
Melanoma
tup05224
Breast cancer
tup05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102473496 (IGF1R)
04014 Ras signaling pathway
102473496 (IGF1R)
04015 Rap1 signaling pathway
102473496 (IGF1R)
04066 HIF-1 signaling pathway
102473496 (IGF1R)
04068 FoxO signaling pathway
102473496 (IGF1R)
04151 PI3K-Akt signaling pathway
102473496 (IGF1R)
04152 AMPK signaling pathway
102473496 (IGF1R)
04150 mTOR signaling pathway
102473496 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
102473496 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102473496 (IGF1R)
04140 Autophagy - animal
102473496 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102473496 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102473496 (IGF1R)
04520 Adherens junction
102473496 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102473496 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102473496 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102473496 (IGF1R)
09156 Nervous system
04730 Long-term depression
102473496 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102473496 (IGF1R)
04213 Longevity regulating pathway - multiple species
102473496 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102473496 (IGF1R)
05202 Transcriptional misregulation in cancer
102473496 (IGF1R)
05205 Proteoglycans in cancer
102473496 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102473496 (IGF1R)
05214 Glioma
102473496 (IGF1R)
05218 Melanoma
102473496 (IGF1R)
05215 Prostate cancer
102473496 (IGF1R)
05224 Breast cancer
102473496 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102473496 (IGF1R)
01522 Endocrine resistance
102473496 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102473496 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tup04090
]
102473496 (IGF1R)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102473496 (IGF1R)
Protein kinases [BR:
tup01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102473496 (IGF1R)
CD molecules [BR:
tup04090
]
Proteins
102473496 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102473496
NCBI-ProteinID:
XP_014448243
LinkDB
All DBs
Position
Un
AA seq
1344 aa
AA seq
DB search
MGQEPARVKISFSLKPCSTLSSHLPAVCGPGIDIRNDYQQLKRLENCTVIEGYLHILLIS
KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNL
KDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGT
MEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACSENSECCHPECLGSCSAPDND
TACVACRHYFYAGVCVPTCPPNTYRFEGWRCVDRDFCANITSAESSDSEGFVIHDGECMQ
ECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTVFKGNLLINIR
RGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDN
QNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGER
ASCESDVLHFTSTTTWKNRIIITWRRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACG
SNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIR
TNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQAPXXXXXXXXXXNY
CSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVF
ENFLHNSIFVPRPERRRRDVTQVANTTMASRSRNTTMVDTYNITDPEELETEYPFFESRV
DNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWES
RPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGNYT
ARIQATSLSGNGSWTDPVFFYVPTKGTYDTFIHLIVALPVAVLLIVGGLVIMLYVYHRKR
NNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVV
KDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGPPTTWVNNPV
LAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYET
DYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLR
FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPGFREVSFYYSE
ENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAENGPGPGVLVLRASFDER
QPYAHMNGGRKNERALPLPQSSTC
NT seq
4035 nt
NT seq
+upstream
nt +downstream
nt
atgggacaggaacccgctagggtaaagatttccttttcactgaagccatgttccaccttg
tcttctcatctccccgcagtctgtgggccgggcattgacatccggaacgactatcagcag
ctgaagcgcttggagaactgcacggtgatcgagggctacctccacatccttctcatctcc
aaggccgaggactaccgcagctaccgcttccccaagctcacggtcatcaccgagtacttg
ctgctgttccgtgtggctggccttgagagcctcggagacctcttcccaaacctcacggtc
atccgcggctggaagctcttctacaactacgccctggtgatcttcgagatgaccaacctc
aaggacattgggctttacaacttgaggaacatcactcggggcgccatcaggatcgagaag
aacgcagacctctgctacctctccaccgttgactggtccctgatcctggacgctgtgtcc
aataactacattgtggggaacaagcccccgaaggaatgtggggatctgtgtcctgggacc
atggaggagaaaccactgtgtgagaagaccaccatcaacaacgagtacaactaccgctgt
tggaccaccaatcgctgccagaaaatgtgcccgagcgcctgcgggaagcgggcgtgctcg
gagaacagtgagtgctgtcaccccgagtgcctgggcagctgcagcgcgcccgacaacgac
acagcctgcgtggcctgccggcactacttctacgccggcgtctgcgtgcccacctgccca
cccaacacctacaggttcgagggctggcgctgcgtggaccgcgacttctgcgccaacatc
accagcgccgagagcagcgactctgaaggcttcgtgatccacgacggcgagtgcatgcag
gagtgcccctcggggttcattcgcaacggcagccagagcatgtactgcatcccctgtgaa
ggcccgtgccccaaggtctgtgaagaagagaagaaaacaaagaccatcgattcggttact
tctgctcaaatgcttcaaggatgcaccgtcttcaagggcaatttgctcattaatatccgc
agaggcaataacatcgcctcggaactggagaacttcatggggctcatcgaggtggtgacg
ggctacgtgaagatccgccattcccatgccttggtctctttgtccttcctcaaaaacctc
cgccagatcttaggagaggagcagttggaagggaactactccttctacgtcctcgacaac
cagaacttgcagcagctgtgggactgggaccaccgcaacctgaccatcaaagcagggaaa
atgtacttcgctttcaaccccaaattgtgcgtttccgaaatctaccgcatggaggaagtg
acggggacgaaagggcggcagagcaaaggagacatcaacaccaggaacaacggggagcga
gcatcctgtgagagcgatgtcctgcatttcacctccaccaccacctggaagaaccgcatc
ataataacctggcgtcgctaccggccccctgactaccgggacctcatcagcttcacagtc
tactacaaggaagcaccctttaaaaacgtgacggagtatgatgggcaggacgcctgtggc
tccaacagctggaacatggtggatgtggacctgccccccaacaaggatgtcgagcctggc
attcttctgcacgggctgaagccctggactcagtacgccgtgtatgtcaaagccgtgacc
ctcaccatggtggagaacgaccacatccgcggggccaagagtgagatcttgtacattcgc
accaatgcttcagttccttccattcccctggatgtcctctcagcctccaactcgtcctcg
cagctgatcgtgaagtggaacccgccctcgctgcccaacggtaacctgagttactacatc
gtgcggtggcagcggcaggccccgnnnnnnnnnnnnnnnnnnnnnnnnnnnnncaactac
tgctccaaagacaaaatccccatcaggaagtatgccgacggcaccattgatgtggaggag
gtgaccgagaaccccaagaccgaagtgtgcggcggggagaaggggccgtgctgcgcatgc
cccaaaaccgaggccgagaagcaggctgagaaagaggaggccgagtaccgcaaagtcttc
gagaacttcctgcacaactccatcttcgtgcccagacctgagaggaggcggagagacgtc
acacaagtggccaacaccaccatggcgagtcgaagcaggaacaccaccatggtggacact
tacaacatcaccgacccggaagagctcgagaccgaatacccgttctttgagagcagagtg
gataacaaagagaggaccgtcatttccaacctccggcctttcactctctaccgcattgac
atccacagctgtaaccatgaggccgagaagctgggctgcagcgcctccaactttgtcttt
gcgagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgggagtcg
aggcctgaaaactccatctttctgaagtggcctgaacccgagaatcccaatggattgatc
ctaatgtatgaaataaaatacgggtcacagatcgaggaccagcgggagtgcgtgtccaga
caggaatacaggaagtacggaggggccaagcttaaccgactaaacccagggaactacaca
gcccggatccaggctacctctctgtctgggaatggctcgtggaccgatcccgtgttcttc
tatgtcccgaccaaaggaacgtacgataccttcatccatctcatcgtcgctctgcctgtc
gctgtcctgctcatcgtgggagggctggtgattatgttgtacgtctaccacaggaagaga
aataacagcaggttgggaaatggagtattgtatgcctctgtgaacccagagtacttcagt
gccgctgatgtgtacgttcccgatgaatgggaagtagcccgggagaagatcaccatgagc
cgagagctcggacaggggtccttcgggatggtctatgagggtgtcgccaagggcgtggtt
aaggacgaacctgaaaccagggtggccatcaagactgtgaacgaggccgcgagcatgcgt
gagaggattgagtttctcaacgaggcgtccgtgatgaaggagttcaactgtcaccacgtg
gtgcgtttgttgggtgtggtgtcccagggcccgccgacaacttgggtgaataacccagtc
ctcgcacctccaagcctcagcaagatgatccagatggctggcgagattgccgacggcatg
gcgtatctcaacgccaacaagttcgtccacagagacctggcagctcggaactgcatggtg
gctgaggatttcaccgtcaaaatcggagacttcgggatgacgcgagacatctacgagacc
gactactaccggaagggcgggaaggggctgctgcccgtgcgctggatgtcacccgagtcc
ctcaaggatggcgtcttcaccacccattccgacgtctggtccttcggggtcgtcctctgg
gaaatcgccacgctggccgagcagccgtaccagggcctgtccaacgagcaggtcctccgc
ttcgtcatggagggtggccttctggacaagccggacaactgccccgacatgctgttcgag
ctgatgcgcatgtgctggcaatacaaccccaagatgcggccatccttcctggagatcatc
ggcagcatcaaagacgagatggagcccggcttccgggaggtctccttctactacagcgaa
gagaacaagccccccgagcccgaggagctggacctggagcccgagaacatggagagcgtc
cccctggacccctcagcctcctcggcctccctgcctctgcccgacagacactcaggacac
aaagccgagaacggcccgggccctggggtgctggtcctccgagccagcttcgacgagaga
cagccttacgcgcacatgaacgggggacgcaagaacgagcgcgccctgccgctgccccag
tcttcgacctgctga
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integrated database retrieval system
