Tupaia chinensis (Chinese tree shrew): 102475423 Help Entry 102475423         CDS       T02978                                  Symbol RPS6KB2 Name (RefSeq) ribosomal protein S6 kinase B2   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup01522   Endocrine resistance tup04012   ErbB signaling pathway tup04066   HIF-1 signaling pathway tup04140   Autophagy - animal tup04150   mTOR signaling pathway tup04151   PI3K-Akt signaling pathway tup04152   AMPK signaling pathway tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04350   TGF-beta signaling pathway tup04371   Apelin signaling pathway tup04666   Fc gamma R-mediated phagocytosis tup04714   Thermogenesis tup04910   Insulin signaling pathway tup04931   Insulin resistance tup05163   Human cytomegalovirus infection tup05165   Human papillomavirus infection tup05170   Human immunodeficiency virus 1 infection tup05200   Pathways in cancer tup05205   Proteoglycans in cancer tup05207   Chemical carcinogenesis - receptor activation tup05210   Colorectal cancer tup05212   Pancreatic cancer tup05221   Acute myeloid leukemia tup05224   Breast cancer tup05225   Hepatocellular carcinoma tup05226   Gastric cancer tup05231   Choline metabolism in cancer tup05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04350 TGF-beta signaling pathway     102475423 (RPS6KB2)    04066 HIF-1 signaling pathway     102475423 (RPS6KB2)    04151 PI3K-Akt signaling pathway     102475423 (RPS6KB2)    04152 AMPK signaling pathway     102475423 (RPS6KB2)    04150 mTOR signaling pathway     102475423 (RPS6KB2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102475423 (RPS6KB2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     102475423 (RPS6KB2)   09149 Aging    04211 Longevity regulating pathway     102475423 (RPS6KB2)    04213 Longevity regulating pathway - multiple species     102475423 (RPS6KB2)   09159 Environmental adaptation    04714 Thermogenesis     102475423 (RPS6KB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102475423 (RPS6KB2)    05205 Proteoglycans in cancer     102475423 (RPS6KB2)    05207 Chemical carcinogenesis - receptor activation     102475423 (RPS6KB2)    05231 Choline metabolism in cancer     102475423 (RPS6KB2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102475423 (RPS6KB2)   09162 Cancer: specific types    05210 Colorectal cancer     102475423 (RPS6KB2)    05212 Pancreatic cancer     102475423 (RPS6KB2)    05225 Hepatocellular carcinoma     102475423 (RPS6KB2)    05226 Gastric cancer     102475423 (RPS6KB2)    05221 Acute myeloid leukemia     102475423 (RPS6KB2)    05224 Breast cancer     102475423 (RPS6KB2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102475423 (RPS6KB2)    05163 Human cytomegalovirus infection     102475423 (RPS6KB2)    05165 Human papillomavirus infection     102475423 (RPS6KB2)   09167 Endocrine and metabolic disease    04931 Insulin resistance     102475423 (RPS6KB2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102475423 (RPS6KB2)    01522 Endocrine resistance     102475423 (RPS6KB2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102475423 (RPS6KB2) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      102475423 (RPS6KB2) Protein kinases [BR:tup01001]  Serine/threonine kinases: AGC group   RSK family [OT]    102475423 (RPS6KB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7 Motif Other DBs NCBI-GeneID:  102475423 NCBI-ProteinID:  XP_006171348 LinkDB All DBs Position Un AA seq 388 aa AA seqDB search MKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELF THLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCK ESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKT MDKIIKGKLVLPPYLTPDARDLVKKFLKRNPSQRIGGGPADAADVQRHPFFRHINWDDLL ARRIDPPFRPSLQSEEDVSQFDTRFTRQTPVDSPDDTSLSESANQAFLGFTYVAPSVLDS IKEGFSFQPKVRSPRRLNSSPRTPISPLKFSPFEGFRPSPGPPEPMEPPLPPLLPPPTPP PPSSTAPLPIRPPSGTKKSKRGRGRPGR NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt atgaaagtcctgaggaaggccaaaatcgtgcgcaatgccaaggacacagcacacacgcgg gctgagcggaatattctagagtcagtgaaacaccccttcattgtggaactggcctatgcc ttccagactggtggcaaactctacctcatcctcgagtgcctcagtggtggtgagctcttc acacatctggagcgagaaggcatcttcctggaagacacggcctgcttctacctagctgag atcacactggccctgggccatctccactcccaaggcatcatctaccgagacctcaaacct gagaacatcatgctcaacagccagggccacatcaaactgacagacttcgggctctgcaag gagtccatccacgagggtgctgtcactcacaccttctgcggcaccattgagtacatggct cctgagattctggtgcgcagtggccacaaccgggcggtggactggtggagtttgggggcc ctgatgtacgacatgctcactggatcgccaccctttactgcagagaaccggaagaaaacc atggataagattatcaagggaaagctggtgctgcccccctacctcacgccagatgcccgg gatctagtcaaaaagtttctgaagcggaatcccagccaacggattgggggtggccctgca gatgctgctgatgtgcagaggcaccctttcttccggcatatcaattgggatgacctcctg gcccgccgcatagacccccctttcaggccctctctgcagtccgaggaggacgtgagccag tttgacacacgcttcacgcggcagacaccagtggacagtccagatgacacatccctcagc gagagtgccaatcaggccttcctgggcttcacatacgtggcgccctccgtcctggacagc ataaaggagggcttctccttccaacccaaggtgcgctccccccgacgcctcaacagcagt ccccggacccccatcagccccctcaagttctcccccttcgaggggttccggcccagccct ggcccaccagagcccatggagccacctctccctccactcctgccaccaccgacgccgcca ccaccttcaagcactgcccccctccccatccgtcctccctcagggaccaagaagtccaag aggggccgtgggcgccctgggcgctag

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