Tupaia chinensis (Chinese tree shrew): 102477344 Help Entry 102477344         CDS       T02978                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00230   Purine metabolism tup01100   Metabolic pathways tup01522   Endocrine resistance tup04015   Rap1 signaling pathway tup04020   Calcium signaling pathway tup04022   cGMP-PKG signaling pathway tup04024   cAMP signaling pathway tup04062   Chemokine signaling pathway tup04072   Phospholipase D signaling pathway tup04081   Hormone signaling tup04082   Neuroactive ligand signaling tup04114   Oocyte meiosis tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04261   Adrenergic signaling in cardiomyocytes tup04270   Vascular smooth muscle contraction tup04371   Apelin signaling pathway tup04540   Gap junction tup04611   Platelet activation tup04713   Circadian entrainment tup04714   Thermogenesis tup04723   Retrograde endocannabinoid signaling tup04724   Glutamatergic synapse tup04725   Cholinergic synapse tup04727   GABAergic synapse tup04750   Inflammatory mediator regulation of TRP channels tup04911   Insulin secretion tup04912   GnRH signaling pathway tup04913   Ovarian steroidogenesis tup04914   Progesterone-mediated oocyte maturation tup04915   Estrogen signaling pathway tup04916   Melanogenesis tup04918   Thyroid hormone synthesis tup04921   Oxytocin signaling pathway tup04923   Regulation of lipolysis in adipocytes tup04925   Aldosterone synthesis and secretion tup04926   Relaxin signaling pathway tup04927   Cortisol synthesis and secretion tup04928   Parathyroid hormone synthesis, secretion and action tup04934   Cushing syndrome tup04935   Growth hormone synthesis, secretion and action tup04961   Endocrine and other factor-regulated calcium reabsorption tup04962   Vasopressin-regulated water reabsorption tup04970   Salivary secretion tup04971   Gastric acid secretion tup04972   Pancreatic secretion tup04976   Bile secretion tup05032   Morphine addiction tup05163   Human cytomegalovirus infection tup05166   Human T-cell leukemia virus 1 infection tup05200   Pathways in cancer tup05207   Chemical carcinogenesis - receptor activation tup05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102477344 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102477344 (ADCY9)    04371 Apelin signaling pathway     102477344 (ADCY9)    04020 Calcium signaling pathway     102477344 (ADCY9)    04072 Phospholipase D signaling pathway     102477344 (ADCY9)    04024 cAMP signaling pathway     102477344 (ADCY9)    04022 cGMP-PKG signaling pathway     102477344 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102477344 (ADCY9)    04081 Hormone signaling     102477344 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102477344 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     102477344 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102477344 (ADCY9)    04062 Chemokine signaling pathway     102477344 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     102477344 (ADCY9)    04923 Regulation of lipolysis in adipocytes     102477344 (ADCY9)    04912 GnRH signaling pathway     102477344 (ADCY9)    04913 Ovarian steroidogenesis     102477344 (ADCY9)    04915 Estrogen signaling pathway     102477344 (ADCY9)    04914 Progesterone-mediated oocyte maturation     102477344 (ADCY9)    04921 Oxytocin signaling pathway     102477344 (ADCY9)    04926 Relaxin signaling pathway     102477344 (ADCY9)    04935 Growth hormone synthesis, secretion and action     102477344 (ADCY9)    04918 Thyroid hormone synthesis     102477344 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     102477344 (ADCY9)    04916 Melanogenesis     102477344 (ADCY9)    04925 Aldosterone synthesis and secretion     102477344 (ADCY9)    04927 Cortisol synthesis and secretion     102477344 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102477344 (ADCY9)    04270 Vascular smooth muscle contraction     102477344 (ADCY9)   09154 Digestive system    04970 Salivary secretion     102477344 (ADCY9)    04971 Gastric acid secretion     102477344 (ADCY9)    04972 Pancreatic secretion     102477344 (ADCY9)    04976 Bile secretion     102477344 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102477344 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     102477344 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     102477344 (ADCY9)    04727 GABAergic synapse     102477344 (ADCY9)    04725 Cholinergic synapse     102477344 (ADCY9)    04723 Retrograde endocannabinoid signaling     102477344 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102477344 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     102477344 (ADCY9)    04213 Longevity regulating pathway - multiple species     102477344 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     102477344 (ADCY9)    04714 Thermogenesis     102477344 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102477344 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     102477344 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102477344 (ADCY9)    05163 Human cytomegalovirus infection     102477344 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     102477344 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102477344 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102477344 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102477344 (ADCY9) Enzymes [BR:tup01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102477344 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  102477344 NCBI-ProteinID:  XP_006140810 LinkDB All DBs Position Un AA seq 1353 aa AA seqDB search MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSQPKHCKYSISSSCSSSGDS GGLPRRVGGGGRLRRQRKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYIGFACLLWSIYFAVHMRAKLIVMVAPALCFLAVCVGFFLFTFTKLYARHYAWTSLVLT LLVFTLTLAAQFQVLTPLSGRVDSSNHTAAAKSTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFRDEDCFPWPGARALHWELLGRALLHVCIHAIGVHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMRQGDEESENSVKR HATSSPKNRKKKSSIQKTPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEAIGSSRVS SGPRGQGTASSGSVSDLAQTVQTFDNLKTCPSCGITFAPKAEASAEGGAVQNGCPDERAN STKASGGSNAKTQNGLLSPPQEEKLTSSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVVKNSPVKTF ASATFSSLLDVFLSTTVFLILSVTCFLKYGATATPPPPAALAVFGAALLLELLSLAVSIR MVFFLEDVMACTKRLLEWVAGWLPRHCIGAVLVSLPALAVYSHVTSEFERNVHVTVFTGS AVLVAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYISLCPDSSIVMSPLDAVQNFSSGR SPCDSSLLRADGRPATLIGQELILVFFPLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPGYSSIEKIKTIGATYMAASGLNTAQRQDGSHPQEHLQVLFE FAKEMMRVVDDFNNNMLWFNFKLRVGFHHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESFRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCAGNGVVPQHQLSISP DIRVQVDGSIGRSPTDEIASLVLAGQYSDKVSLGSASSTQAKDAHLASERAWREPASTEE RCRLGKAAERNGCEEPGVDEADELTKLNVSKSV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcctcccctccccaccagcagctgctgcatcaccacagcaccgaggtgagctgcgac tccagcggggacagcaacagcgtgagggtcaagatcaaccccaagcagctgtcctccaac agccagcccaagcactgcaagtacagcatctcttccagctgcagcagctccggggactcc ggggggctcccccggagagtgggcggtgggggccgcctgcgcaggcagaggaagctgccc cagcttttcgagagggcttccagcaggtggtgggaccccaagttcgactccgtgaacctg gaggaggcctgcctggagcgctgcttcccgcagacccagcgccggttccgatacgcgctt ttctacatcggcttcgcctgccttctctggagcatctattttgctgtccacatgagagcc aaactgatcgtcatggttgccccggctctgtgcttcctagcggtatgcgtgggctttttt ctgtttaccttcaccaagctgtatgcccggcactacgcctggacctcgctggttctcacc ctgctggtgttcaccctaaccctggctgcgcagtttcaggttttgacgcctctctcagga cgtgttgacagctccaatcacactgctgcagccaaatccacagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagtgctctttttgctctacaccgtcatgcactta cccttgtacttgagtttgtttctgggggtggcctattcggttctctttgagacctttggc taccatttccgagatgaagactgcttcccctggcctggagcccgggccctgcactgggag ctgctgggcagggccctgctgcacgtctgcatccacgccatcggggtccacctcttcatc atgtctcaggtgcggtccaggagcaccttcctcaaggtgggacagtcgatcatgcatggg aaagacctagaagtagagaaagccctgaaagaaaggatgattcattctgtgatgccgaga atcatagctgatgacctcatgagacagggggacgaggagagcgagaattctgtcaaaagg catgccacctccagtcccaagaacaggaagaaaaagtcttccatacagaaaactcccatc gcattccgccctttcaagatgcagcagattgaagaagtcagtattttatttgcagatatc gtgggttttaccaagatgagtgccaacaagtctgctcacgccctggtgggtctcctgaat gatctgtttggtcgctttgaccgcttgtgtgaagagaccaagtgtgagaagatcagcacc ctgggagactgctactactgcgtggcaggctgtcccgagccccgggcagaccatgcctac tgctgcatcgagatggggttaggcatgataaaggccattgagcagttctgccaggagaag aaggaaatggtgaacatgcgtgttggggttcacacggggactgtcttgtgtggcattttg ggaatgaggaggttcaaattcgacgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtagccggcaaagttcacatttccgaggccacagcaaaatacttagat gaccggtacgaaatggaagatgggaaagttattgagcgccttggccagagtgtagttgct gaccagttgaaaggtttgaagacatacctgatatcgggtcagagagccaaggagtctcac tgcagctgtgcagaggccttgctttctggctttgaggccattggcagctcccgggtgtcc tcaggccctaggggacaggggacagcatcatcagggagtgtcagtgacttggcgcagact gtccaaacctttgataaccttaagacctgcccgtcgtgtggaatcacctttgctcccaaa gctgaagccagtgcagaaggaggcgctgtccagaacggctgtccagacgagcgtgcgaac agcaccaaggcttctggaggatctaatgccaaaactcagaatggccttctgagccctccc caagaggagaagctcactagcagtcagacctcgctgtgtgagatcttacaggaaaagggg aggtgggcaggggtcagcttggaccagtcggctctccttccgctgagattcaagaacatc cgcgagaagaccgacgcccactttgtggatgtcatcaaagaagacagcctgatgaaagac tacttttttaagccgcccattaaccagttcagcctgaacttcctggatcaggagctggag cgatcctacaggaccagctatcaggaagaggtcgtgaagaactctcctgtgaagactttc gccagtgccaccttcagctccctcctggacgtgttcctgtccacaacggtattcctcatc ctgtctgtcacctgcttcctgaagtacggggccaccgccacgcctcccccgcccgccgcg ctggccgtcttcggggcggccttgctgctggagctgctgtccctggccgtgtccatcagg atggtgtttttcctggaagacgtgatggcttgcacgaagcgcctgctggagtgggtggcc ggctggctcccacgccactgcatcggggccgtgctggtgtcactgcccgccctcgcagtc tactctcacgtcacctccgagtttgagagaaacgtgcatgtcacggtgttcacgggctcc gccgtgctggtggccgtcgtgcactactgcaacttctgccagctcagctcctggatgagg tcgtccctcgccaccgtcgtgggggccgggccgctgctcctgctgtacatctccctgtgc cccgacagttccatagtaatgtctcccctcgatgcagtacagaatttcagctccgggagg agtccatgcgacagctcgttgctgcgggccgacggaagaccagccaccctcatcggccag gagctgatcttggtcttcttcccgctgctcttgctggtctggttcctgaaccgcgagttc gaggtcagctaccgccttcactaccacggggacgtggaggcggacctgcaccgcaccaag atccagagcatgagggaccaggccgactggctgctcaggaacatcatcccctaccacgtg gccgagcagctgaaggtgtcacagacctactccaagaaccacgacagcggcggcgtgatc tttgccagcatcgtcaacttcagcgagttctacgaggagaactacgagggcggcaaggag tgctaccgcgtcctcaacgagctgatcggggacttcgacgagctcctgagcaagccgggc tacagcagcatcgagaagatcaagaccatcggggccacctacatggcggcgtcggggctg aacacggcgcagcgccaggatggcagccacccgcaggagcacctgcaggtcctgttcgag ttcgccaaggagatgatgcgcgtggtggacgacttcaacaacaacatgctgtggttcaac ttcaagctcagagtgggcttccaccacgggcccctcacggcgggcgtcatcggcaccacc aagctgctgtacgacatctggggggacacggtcaacatcgccagcaggatggacaccacc ggcgtcgagtgccgcatccaggtgagcgaggagagcttccgcgtcttgagcaagatgggc tatgacttcgactaccgggggacggtgaacgtcaaggggaagggccagatgaagacctac ctttaccccaagtgcgcgggcaatggggtggtgccgcagcaccaactgtccatctccccc gacatccgcgtgcaggtggacggcagcatcggacgctcgcccacagacgagatcgccagc ctggtgctggccgggcagtactcggacaaggtgtccctgggctccgccagcagcactcag gccaaggatgctcacctggcctctgagagagcctggagggagcccgccagcaccgaagag aggtgccgacttggcaaagccgcagagagaaacggctgcgaggagccgggggtggacgaa gccgatgaactcaccaagctcaatgtctcaaagagcgtgtga

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