Tupaia chinensis (Chinese tree shrew): 102480558 Help Entry 102480558         CDS       T02978                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase 1   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00220   Arginine biosynthesis tup00330   Arginine and proline metabolism tup01100   Metabolic pathways tup04020   Calcium signaling pathway tup04081   Hormone signaling tup04145   Phagosome tup04371   Apelin signaling pathway tup04713   Circadian entrainment tup04730   Long-term depression tup04926   Relaxin signaling pathway tup04970   Salivary secretion tup05010   Alzheimer disease tup05014   Amyotrophic lateral sclerosis tup05022   Pathways of neurodegeneration - multiple diseases tup05410   Hypertrophic cardiomyopathy tup05412   Arrhythmogenic right ventricular cardiomyopathy tup05414   Dilated cardiomyopathy tup05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     102480558 (NOS1)    00330 Arginine and proline metabolism     102480558 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     102480558 (NOS1)    04020 Calcium signaling pathway     102480558 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102480558 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102480558 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     102480558 (NOS1)   09154 Digestive system    04970 Salivary secretion     102480558 (NOS1)   09156 Nervous system    04730 Long-term depression     102480558 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     102480558 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102480558 (NOS1)    05014 Amyotrophic lateral sclerosis     102480558 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     102480558 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     102480558 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     102480558 (NOS1)    05414 Dilated cardiomyopathy     102480558 (NOS1)    05416 Viral myocarditis     102480558 (NOS1) Enzymes [BR:tup01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      102480558 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  102480558 NCBI-ProteinID:  XP_006151632 LinkDB All DBs Position Un AA seq 1475 aa AA seqDB search MEDHVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTQPLGTPTKAVDLSHQPLASKEQPLLVDGATGPRGRVQHAQDNGQEARSLTHANGLAP RPASQDSDKKSARVGIQGSGENSELLKEIEPVLNLLTSGSHGVNGGGPAKAEMKDTGIQV DRDVDSKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS KCPRFLKVKNWETNMVLTDTLHLKSTLETGCTEHICMGSIMHPSQHVRRPEDVRTKEQLF PLAKEFIDQYYSSIKRFGSKAHMDRLEEVNKELETTSTYQLKDTELIYGAKHAWRNAARC VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW NSQLIRYAGYKQPDGSTLGDPANVEFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ EERKYPEPLRFFPRKGPSLSHGNTEVQGLAAARDSQHRSYKVRFNSVSSYSDSRKSSGDG PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT QGLSNVHRKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHE DLVNALIERLEDAPPANQMVKVELLEXXXXXXXXXXXALGVISNWTDEHRLPPCTIFQAF KYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFP SIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSW LNRIQADEVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSP CPMVLVFGCRQSKIDHIYKEETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAEP VYRALKEQGGHVYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDI FGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4428 nt NT seq  +upstreamnt  +downstreamnt atggaggatcacgtgttcagtgtccagcaaatccagcccaatgtcatttctgtccgcctc ttcaaacgcaaagtagggggcctgggattcctggtaaaggaacgggtcagcaagccacca gtgatcatctccgacctgatccgtgggggtgccgcggagcagagtggcctcatccaggcc ggggacatcattctcgccgtcaatggccggcccttggtggaccttagctacgatagtgcc ctagaggtgctcaggggcatcgcctctgagacccatgtggttctcattttgaggggccct gagggctttactacgcacctggagaccaccttcaccggagacgggacccccaagactatc cgggtgactcagcctctaggtacccccaccaaggcggtcgatctctctcaccagccactg gccagcaaagagcagccactgctggtagatggggccacaggtcccaggggcagagttcag catgcccaagacaatgggcaggaagccagatcactcacccatgccaatggcctggccccc aggcccgcaagccaggattctgacaagaaaagtgcccgggtgggcatccagggcagtggg gagaacagtgagctgctcaaggagatagagcctgtgctgaaccttctcaccagtgggagc cacggggtcaacggagggggacctgccaaagcagagatgaaagacacaggcatccaggtg gacagagatgtggacagcaagtcacacaaacctctgcccctcggcgtggagaatgaccga gtcttcaatgacctgtggggaaagggcaatgtccccgtggtcctcaacaacccgtattca gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccatct aagtgtcctcgctttctcaaggtcaagaactgggagaccaacatggttctcacggatacc cttcacctgaagagcacgttggaaacaggctgcaccgagcacatctgcatgggctccatt atgcacccttcccagcacgttcgacggcccgaagatgtccgcacaaaggagcagctcttc cctctcgccaaagagtttatcgaccagtactactcgtcaattaaaagatttggctccaaa gctcacatggatcgcctggaagaggtgaacaaagaactcgagaccaccagcacctaccag ctcaaggacactgagctcatctacggggccaagcacgcctggcggaacgccgcccgctgc gttggcaggatccagtggtccaagctacaggtgttcgatgcccgtgattgtactactgct catgggatgttcaactacatctgcaaccacgtcaaatacgccaccaacaagggcaacctc aggtctgccatcactatatttccccagaggacagatggcaagcatgacttccgcgtctgg aactcccagctcatccgctatgctggctacaaacagcctgatggctccaccctgggagat ccagccaatgtggagttcacagagatttgcatacagcagggctggaaagccccgagaggc cgttttgatgtccttccactcttgctccaagccaacggcaatgaccccgagctcttccag attcctccagagctagtgttggaagtacccatcaggcaccccaagttcgagtggttcaag gacctggggctgaagtggtacggcctgcctgcggtgtccaacatgctgctggagattggg ggcctggagttcagcgcctgtcccttcagcggctggtatatgggcacagagattggcgtc cgcgactactgtgacaattcccgctacaacatcctggaggaagtagccaagaagatgaac ttggacatgaggaagacgtcctccctgtggaaggaccaggcactggtggagatcaatatc gctgttctctacagcttccagagtgacaaagtgaccatcgttgaccatcactctgccact gagtccttcattaaacacatggagaatgaataccgctgtcgggggggctgccctgctgac tgggtgtggatagtaccccccatgtctggcagcatcacccctgtcttccaccaggagatg ctcaactaccggctcaccccctcttttgaataccagcctgatccttggaacacccatgtc tggaaaggcaccaacgggacccccacaaagcggcgagccattggcttcaaaaagctggca gaagctgtcaaattctcagccaagctgatggggcaggcaatggccaagagggtcaaagcg accatcctctatgccaccgagacgggcaaatcacaagcctatgccaagaccttgtgtgag atcttcaaacacgccttcgatgccaaggtgatgtccatggaagaatatgacattgtacac ctggaacatgaaactctggtcctggtggtcaccagcacctttggcaatggggacccccct gagaatggagagaaattcggctgtgctttgatggaaatgaggcaccccaactctgtgcaa gaagaaaggaagtacccggaacccttgcgtttctttccccgtaaagggccttccctctcc catggcaacacagaagtccaaggtctggctgcagcccgtgacagccagcacaggagctac aaggtccgattcaatagtgtctcttcctactctgactcccgcaaatcatcaggggatggg cccgacctcagagacaactttgaaagtgctggacctctggctaacgtgaggttctcggtg tttggccttggctcgcgggcataccctcacttctgcgcctttggtcatgctgtggacacc ctcctggaagagttgggaggggagaggatcctgaagatgagggagggagatgagctctgt gggcaggaagaggctttcaggacctgggccaagaaggtcttcaaggcagcctgcgatgtg ttctgtgtgggagatgatgtcaatatcgagaaggcaaacaactccctcatcagcaacgac cgcagctggaagaggaacaagttccgcctcacctatgtggctgaagctccagaactcaca caaggtctatccaatgtccaccgaaagcgagtctctgctgctcgactcctcagccgtcaa aacctccagagtcctaagtccagccgatcaactatcttcgtgcgtctccacactaatggg aatcaggaactgcagtaccagcccggggaccacctgggcgtcttccctggcaatcatgag gaccttgtgaatgccctgattgagcggctggaggatgcaccccctgccaaccagatggtg aaagtggagctgctggaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnncagctttgggt gtcatcagtaactggacagacgaacaccgtcttccgccctgcaccatcttccaggccttc aagtattatctggacatcacgacgccgccaacgcctctgcagctgcagcagtttgcctcc ctggccaccagtgagaaagaaaagcagcgactactggttctcagcaagggtttgcaggag tatgaggaatggaaatggggcaagaaccccaccatcgtggaggtgttggaggagttcccg tccatccagatgcctgccaccctgctcctgacccagctgtcgctgctgcagcctcgctac tattccatcagttcctccccagacatgtaccccgacgaggtgcacctcactgtggccatc gtctcctaccgcacccgagatggagaaggaccaattcaccatggcgtgtgctcttcctgg ctcaaccggatacaggccgatgaagtggttccctgttttgtaagaggtgcacccagcttc cacctgccccgaaacccccaagtcccctgcatcctggttggcccaggcactggcatcgcc cccttccgaagcttctggcagcagcggcaatttgatatccagcacaaaggaatgagtccc tgccccatggttctggtcttcgggtgccggcagtccaagatagatcacatctacaaggag gagaccctacaggccaaaaacaagggggtcttcagagagctctacacagcctactcacgg gagccagacaaaccaaagaaatatgtgcaggacatcctgcaagaacagcttgctgaacct gtgtaccgagccctgaaggagcaagggggccacgtttatgtctgtggggatgtcaccatg gccgccgacgtcctcaaagccatccagcgcatcatgacccagcaggggaagctctcggcg gaggacgctggcgtgttcatcagcaggctgagagatgacaaccggtaccacgaggatatt ttcggagtcaccctgagaacatatgaagtgaccaaccgccttagatctgagtccattgcc ttcatcgaagagagcaaaaaagacaccgatgaggttttcagctcctaa

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