Tupaia chinensis (Chinese tree shrew): 102484276 Help Entry 102484276         CDS       T02978                                  Symbol TSC2, Tuberin Name (RefSeq) tuberous sclerosis 2   KO K07207   tuberous sclerosis 2 Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup04072   Phospholipase D signaling pathway tup04115   p53 signaling pathway tup04140   Autophagy - animal tup04150   mTOR signaling pathway tup04151   PI3K-Akt signaling pathway tup04152   AMPK signaling pathway tup04211   Longevity regulating pathway tup04218   Cellular senescence tup04714   Thermogenesis tup04910   Insulin signaling pathway tup04919   Thyroid hormone signaling pathway tup05163   Human cytomegalovirus infection tup05165   Human papillomavirus infection tup05168   Herpes simplex virus 1 infection tup05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     102484276 (TSC2)    04151 PI3K-Akt signaling pathway     102484276 (TSC2)    04152 AMPK signaling pathway     102484276 (TSC2)    04150 mTOR signaling pathway     102484276 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102484276 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     102484276 (TSC2)    04218 Cellular senescence     102484276 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102484276 (TSC2)    04919 Thyroid hormone signaling pathway     102484276 (TSC2)   09149 Aging    04211 Longevity regulating pathway     102484276 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     102484276 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     102484276 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     102484276 (TSC2)    05163 Human cytomegalovirus infection     102484276 (TSC2)    05165 Human papillomavirus infection     102484276 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:tup01009]     102484276 (TSC2) Protein phosphatases and associated proteins [BR:tup01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102484276 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 HEAT Motif Other DBs NCBI-GeneID:  102484276 NCBI-ProteinID:  XP_014442478 LinkDB All DBs Position Un AA seq 1793 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPSPRSAEGRHTEFIVTADILRELSVECGLNNRIRV IGQICEVAKTKRFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMEVGLSSEFLLVL VNLVKFNSCYLDEYIAPMVHMICLLCVRTASAVDIEVSLQVLDAVVCYNCLPAGTLPLFV VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEGRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPTSVLPSFYEAMTCPNEVVSYEVVLSITRLIKKYRKELQAVTWDL LLNIMERLLQQLPCLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVEKCAGQRPE SSLLNLVSYRAQSIHPAKDGWIQSLQSLMERFFRSEPRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPDLEEGARATYSTSLEDVKTAVLGLLVILQTKLYTLPASHAVRVYARVCETLVGHLEL HYRHGYTLPVAASIRLQAFDFLLLLRADSLHRLGLPNKDGIVRFSPYCVCDCVEPERGAE KKASGPLSPPAGPPGPVPAGPAVRLGRLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPES LRYKVLVFTSPCSVDQLSSALCAMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISY HSYLDKTKQREVVYCLEQGLVYRCAGQCVLALAVCSVEMPDIIVKALPVLVVKLTHISAT ASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMW FIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSVRIARPPKHG SSHSPPVREREESAASEAFRCRSVSVSERVVRSRIQTSLTSASLGSADESSMAQADDSLR NLHLELTETCLDMMARYVFSNFTAVPRRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTG TRSLLGLDSGELQSGPESSADPGVRVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHG LRAGALDAPTSHFPSSPAAPGPQAAPVSKPEKASASTQAPASAKSNLAAYVPLLTQGWAE ILVRRPTGNTSWLMSLENPLSPFSSDIDNMPLQELSNALMAAERFKEHRDTALYKSLSVP AASTAKPPPLPRSNTVASLSSLCPAGCPGALRRSVSWADSAVVLEEGSPGETQVPVEPPE FEDFEAALATDQPCQHADVYSRSSSASSQEEKLSHAEGLAAGGIPIERAVCLEGGRPSVD LPFQPSQPLSKSSSSPELQTLQDVLGDPADKADVGRLSPEAKARSQSGTLGGEGAGWSAP GGENRGPGPAPPEGPMPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRAAASNA EKVPGINPSFVFLQLYHSPFFGDESNKPVLLPSEPFERSVQLLDQIPPYDTHKIAVLYVG EGQSSSELAILSNEHGSYRYAEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWH DDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHV IITPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSSST NPHPPTPTLPLAQAHPPAHSKAPAQVPAEPTPAYETGQRKRLLSSVDDFTEFV NT seq 5382 nt NT seq  +upstreamnt  +downstreamnt atggccaagccagcaagcaaggattcaggcctgaaggagaagttcaagatcctgctggga ctggggacgccgaggccgagccccaggtcggcggagggcaggcacacggagttcatcgtc acggccgacatcctccgggaactgagtgtggagtgtggcctcaataatcgcattcgggtc atagggcagatctgcgaagtggcaaaaacaaagagatttgaagagcatgcggtagaagcc ctctggaaagccgtcgcggacctgctgcaaccggagcggccaccagaggcccggcatgcg gtgctggccctgctgaaggccattgttcaggggcagggcgatcgcttgggggtcctcaga gccctcttctttaaggtcatcaaggattacccctccaacgaagacctccatgagcggctg gaggtgttcaaggccctcacggacaacgggaggcacatcacgtacttggaggaagagctg gccgagttcgtgctgcagtggatggaggtcggcctgtcctcggagtttctgctcgtgctg gtcaacttggtcaagttcaacagctgctacctggacgagtacatcgcgccgatggttcac atgatctgcctgctatgtgtccggactgcctcagctgtggacatagaggtctccctgcag gtgctggatgctgttgtttgctacaactgtctgccggctgggaccctgcccctgttcgtt gtcaccctttgccgaaccgtcaacgtcaaggagctctgtgagccctgctggaagctcatg cggaacctcctgggcacccacctgggccacagcgccatctacaacatgtgccgcatcatg gagggcagagcctacatggaggatgccccgctgctgcggggagctgtgttctttgtgggc atggcgctctggggggcccaccggctctactcgctcaggaactcgcccacgtccgtgctg ccgtcgttttatgaggctatgacctgcccgaacgaggtggtgtcctacgaggtcgtcctg tccatcaccaggctcatcaagaagtaccggaaagagctgcaggccgtgacatgggacctc ctgctcaacatcatggagcggctgctgcagcagctcccgtgtctagacagcccggagctc agggccatcgttcacgacctgctgaccacggtggaggagctgtgtgaccagaacgagttc cacggctcgcaggagaggtacttcgagctggtggagaagtgtgcgggccagaggccggag tcctccctcttgaacttggtatcctaccgagcccagtccattcacccggccaaggacggc tggatccagagcctgcagtcgctgatggagaggttcttcaggagcgagccgcgcagtgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacagacagttctac gaggaggagctgatcaactcggtggtcatctcacagctctcccacatccccgaggataag gacccccaggtccgaaagctggccacccagttgctggtggacctggcagagggctgtcac actcaccacttcaacagcctgctggacatcatcgagaaggtgatggcccgctcgctctct ccaccccctgacctggaagaaggggccagggccacctactcgacctccttggaggacgtg aagactgcagtcctcgggctcctggtcatcctgcagaccaagctgtacaccctgcctgcc agccacgccgtgcgcgtgtacgcgcgggtgtgcgagacgctcgtcggccaccttgagctg cactacaggcacggctacaccctgcccgtcgccgccagcatccggctgcaggccttcgac ttcctgctgctgctacgggctgactcgctgcatcgcctcggcctgcccaacaaggacggc atcgtgagattcagcccctactgcgtctgcgactgcgtggagccagagagaggcgctgag aagaaggccagcggtcccctctcgcctcctgcagggccgcctggcccggtgcctgcaggc cctgccgtgcggctcggccgcctgccctactccctgctcttccgtgtcttgctgcagtgt ctgaagcaggagaccgactggaaggtgctgaagctggtgctcagcaagctgcctgagtcg ctgcgctacaaggtccttgtcttcacctccccgtgcagcgtcgaccagctgtcttccgcc ctctgcgccatgctttcaggccccaagaccctcgaacgactccgaggcaccccggaaggg ttctccagaaccgacctgcatttggccgtggtccccgtgctgacggcgctgatctcctac cacagctacctggataagaccaagcagcgcgaggtggtgtactgcctggagcagggcctc gtgtaccgctgcgctggccagtgcgtgctggccctggcggtctgcagcgtagagatgccc gacatcatcgtcaaggcgctgccagtcctggtggtgaagctcactcacatctcagccaca gccagcatggccgtcccgctgctggagttcctgtccactctggccaggctgcctcacctc tacaggaactttgccgcggagcagtacgccagcgtgtttgccatctccctgccttacacc aacccctccaagttcaatcagtacatcgtgtgcctggcccaccacgtcatagccatgtgg ttcatcaggtgccgcctgcccttccggaaagactttgtcccttacatcaccaagggcctg cgctctaatgtcctcctgtcattcgatgacacccctgagaaagacagcttccgagcacgg agcaccagcctcaacgagaggcccaagagtgtgaggatagccagaccccccaaacacggc tcgagtcactccccgcccgtgagagaacgcgaggagagcgctgcatccgaggccttccgg tgccgcagcgtcagtgtgtctgagcgcgtggtccgcagcaggatccagacgtcactcacc agtgccagcctggggtctgccgacgagagctccatggcgcaggctgacgacagcctgaga aacctccacctggagctcaccgagacatgtctggacatgatggcccgttacgtgttctcc aacttcacggccgtccctaggaggtctcccgtgggcgagttcctcctggcaggcggcagg actaagacctggctggtggggaacaagcttgtcaccgtaacaacaagcgtgggcaccggg acccggtcgttgctgggcctggactcaggggagctgcagagtggcccagagtcgagcgct gaccctggtgtgcgtgtgaggcagaccaaagaggcgccggccaagctggagtcccaggct gggcagcaggtgtcccgcggggcccgggaccgcgtccgctccatgtcggggggccacggc cttcgtgccggggccctggacgcaccgacctcccacttcccaagcagccctgctgctcca ggcccgcaggctgccccagtctccaagcccgagaaggcctctgcgagcacccaggccccg gcctcggccaagtccaacctggccgcctatgtgcccctgctgacccagggctgggcggag atcttggtccggagacccacaggaaacaccagctggttgatgagcctggagaacccgctc agccccttctcctcggacatcgacaacatgcccctgcaggagctgtctaacgccctgatg gcagccgagcgcttcaaggagcaccgcgacaccgccctgtataagtcgctgtcggtgccg gccgctagcacagccaagccccctccactcccacgctccaacacagtggcctctctgtcc tccctgtgcccagctggctgcccgggagcactgcgcaggagcgtctcctgggcagactcc gcagtggtcctggaggaggggagtccaggcgagacgcaggtgccagtggagcccccagag ttcgaggacttcgaggcggccctggccacagaccagccctgccaacacgctgacgtgtac agcaggtcatcgtcggcatccagccaggaggagaagctgtcccacgcagaggggctggct gccgggggcatccccatcgagcgggcagtgtgcctggagggaggccggccctctgtggac ctccctttccagccctcacagcctctgagcaagtccagttcgtcacctgagctgcagacc ttgcaggacgtccttggggaccctgcggacaaggctgatgtcggccggctgagccctgaa gccaaggctcggtcacagtccggaaccctgggtggggaaggtgccggctggtctgcccca ggcggagagaaccggggcccaggcccggccccacctgagggccccatgccttccagctct ccccgctcacccagcggcctccggccccgaggttacaccatctccgattcggccccgtca cgcaggggcaagagggtggagagggatgcctttaagagcagagccgcagcctctaatgcc gagaaagtgccgggtatcaaccccagcttcgtgttcctgcagctgtaccactcgcccttc tttggagatgagtccaacaagcccgtcctgctgcccagtgagcccttcgagcggtcagtg cagctgctggatcagatcccgccgtacgacacgcacaagatcgcagtgctgtatgtgggg gaaggccagagcagcagcgagctcgccatcctgtccaacgagcacggctcctacaggtac gcggagttcctgacgggcctgggcaagctcatcgagctcaaggactgccagccggacaag gtgtacctgggcggcctggacgtgtgcggcgaggacggccagttcacctactgctggcac gacgacatcatgcaagccgtcttccacattgccaccctgatgcccaccaaggacgtggac aagcaccgctgtgacaagaagcgccacttgggcaacgacttcgtctctatcgtctacaac gactctggcgaggacttcaagctgggcacaatcaaaggccagttcaacttcgtccacgtg atcatcacccccctggactatgagtgcaacctggtgtcactgcagtgcaggaaagacatg gagggccttgtggacaccagcgtggccaagattgtgtctgaccgcaacctgcccttcgtg gcccgccagatggccctgcatgcaaacatggcctcgcaggtgcaccacagcagctccaca aacccccacccccccacccccaccctgccactggcgcaagcgcaccctccagcccacagc aaagccccggcacaggtcccggccgagcccacgccggcctatgagacaggccagcggaag cgcctcctctcctccgtggacgacttcacggagtttgtgtga

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