Tupaia chinensis (Chinese tree shrew): 102484296 Help Entry 102484296         CDS       T02978                                  Symbol SIRT1 Name (RefSeq) sirtuin 1   KO K11411   NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00760   Nicotinate and nicotinamide metabolism tup01100   Metabolic pathways tup04068   FoxO signaling pathway tup04148   Efferocytosis tup04152   AMPK signaling pathway tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04218   Cellular senescence tup04310   Wnt signaling pathway tup04922   Glucagon signaling pathway tup04936   Alcoholic liver disease tup05031   Amphetamine addiction tup05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00760 Nicotinate and nicotinamide metabolism     102484296 (SIRT1)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     102484296 (SIRT1)    04068 FoxO signaling pathway     102484296 (SIRT1)    04152 AMPK signaling pathway     102484296 (SIRT1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102484296 (SIRT1)   09143 Cell growth and death    04218 Cellular senescence     102484296 (SIRT1)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     102484296 (SIRT1)   09149 Aging    04211 Longevity regulating pathway     102484296 (SIRT1)    04213 Longevity regulating pathway - multiple species     102484296 (SIRT1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102484296 (SIRT1)   09165 Substance dependence    05031 Amphetamine addiction     102484296 (SIRT1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102484296 (SIRT1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:tup03036]     102484296 (SIRT1)    03029 Mitochondrial biogenesis [BR:tup03029]     102484296 (SIRT1) Enzymes [BR:tup01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.286  protein acetyllysine N-acetyltransferase      102484296 (SIRT1) Chromosome and associated proteins [BR:tup03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     SIRTs (sirtuins, class III HDACs)      102484296 (SIRT1) Mitochondrial biogenesis [BR:tup03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Other regulator of mitochondrial biogenesis     102484296 (SIRT1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  SIR2 DUF592 Motif Other DBs NCBI-GeneID:  102484296 NCBI-ProteinID:  XP_014443465 LinkDB All DBs Position Un AA seq 744 aa AA seqDB search MADEAALALQPSGSPSAAAEREAASPPAGEPLRKRPRRDGPGPGWSPSEPLGAAPELEGP VAAAGCPAAAAALWREEAAAGGEREAQPAAAAGEGDNGPGLQGLSREPPPADDLYDDDDD DEGEEEDEAAVAAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGP YTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIE DAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRK DPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHG SFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHR AMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDV IINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQRELAHLSELPPTPLHISEDSSSPERT SPPDSSVLITLLDQAAKSNDDSDVSESKGCMEEKSQDIQTSTRNVESVPEQVENADLKDV GSNTGEKNERTSVAETVRKCWPNRLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSED DVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDDADVPERAEGTGFGADGGD QEPVNEAISMKQEVTDMNCPSNKS NT seq 2235 nt NT seq  +upstreamnt  +downstreamnt atggcggacgaggcggcgctcgcccttcagcccagcggctccccctcggctgcggccgaa agggaggccgcgtcgccgcctgctggggagccgctccgcaagaggccgcggagagacggt cccgggcccgggtggagccccagtgagcccctaggggcggctcccgagcttgaggggccg gtggcggccgcgggctgcccggcggccgcggctgcgctgtggcgggaggaggcggcggcg ggcggagagcgagaggcccagccggcggcggcggccggagaaggagacaatgggccgggc ctgcagggcctatcccgggagccgccgccggccgacgacttgtacgacgacgacgacgac gacgagggtgaggaggaggacgaggcggcggtggcggcggccgcgattgggtaccgagat aatcttctgtttggtgatgaaattatcaccaatggttttcattcctgtgaaagtgatgag gatgatagagcctcacatgcaagctctagtgactggactccaaggccacggataggtcca tatacttttgtccagcaacatctcatgatcggcacagatcctcgaacaattctcaaagac ttactaccagaaacaattcctccacctgaattggatgatatgacactgtggcagattgtt attaatatcctttcagaaccaccaaaaaggaaaaaaagaaaagatattaatacaattgaa gatgctgtgaaattactgcaagagtgcaaaaaaataatagttctaactggagctggggta tctgtttcatgtggaatacctgacttcaggtcaagagatggtatttatgctcgccttgca gtagacttcccagatcttccagatcctcaagcaatgtttgatatcgaatatttcagaaaa gatccaagaccattcttcaaattcgcaaaggaaatatatcctggacagttccaaccatct ctctgtcacaaattcatagccttgtcagataaggaaggaaaattacttcgcaactatact cagaacatagatacattggaacaggttgcaggaatccaaaggataattcagtgtcatggc tcctttgcaacagcatcttgcctgatttgtaaatataaagttgactgtgaagctgtacga ggagatatttttaatcaggtagttcctcgatgtcctaggtgcccagctgatgaaccactt gctattatgaaaccagagattgtcttttttggtgaaaatttaccagaacagtttcataga gccatgaagtatgacaaagatgaagttgatctcctcattgttattggatcttccctgaaa gtaagaccagtagcactaattccaagttccataccccatgaagtgcctcagatattaatt aatagggaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgatgtc ataataaatgaattgtgtcataggttaggtggtgaatatgccaaactttgctgtaaccct gtaaagctttcagaaattactgaaaaacctccacgaacacaaagagagttggctcatttg tcagagttaccaccaacacctcttcacatttcagaagactcaagttcaccagaaagaact tcaccgccggattcttcagtgcttattacacttttagaccaagcagctaagagtaatgat gattcagatgtgtctgaatcaaaaggttgtatggaagaaaaatcacaggacatacagact tcaactaggaatgttgaaagtgttcctgaacaggtcgaaaatgcagatttgaaggatgtt ggttcaaatactggggagaaaaatgaaagaacttcagttgctgaaacagtgagaaagtgc tggcccaatagacttgcaaaggagcagattagtaagcggcttgatggtaatcagtatttg tttttaccaccaaatcgttacattttccatggcgctgaggtatattcagactctgaagat gatgtcttatcctccagttcttgtggcagtaacagtgatagtggaacatgccagagtcct agtttagaagaacccatggaagatgagagtgagattgaagaattctacaatggcttggaa gacgatgctgacgttccagagagagctgaaggaactggatttggggctgatggaggtgat caagagccagttaatgaagctatatccatgaaacaggaagtaacagacatgaactgtcca tcaaataaatcataa

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