Tupaia chinensis (Chinese tree shrew): 102484859
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Entry
102484859 CDS
T02978
Symbol
APC
Name
(RefSeq) APC, WNT signaling pathway regulator
KO
K02085
adenomatosis polyposis coli protein
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup04310
Wnt signaling pathway
tup04390
Hippo signaling pathway
tup04550
Signaling pathways regulating pluripotency of stem cells
tup04810
Regulation of actin cytoskeleton
tup04934
Cushing syndrome
tup05010
Alzheimer disease
tup05022
Pathways of neurodegeneration - multiple diseases
tup05165
Human papillomavirus infection
tup05200
Pathways in cancer
tup05206
MicroRNAs in cancer
tup05210
Colorectal cancer
tup05213
Endometrial cancer
tup05217
Basal cell carcinoma
tup05224
Breast cancer
tup05225
Hepatocellular carcinoma
tup05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
102484859 (APC)
04390 Hippo signaling pathway
102484859 (APC)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102484859 (APC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102484859 (APC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102484859 (APC)
05206 MicroRNAs in cancer
102484859 (APC)
09162 Cancer: specific types
05210 Colorectal cancer
102484859 (APC)
05225 Hepatocellular carcinoma
102484859 (APC)
05226 Gastric cancer
102484859 (APC)
05217 Basal cell carcinoma
102484859 (APC)
05213 Endometrial cancer
102484859 (APC)
05224 Breast cancer
102484859 (APC)
09172 Infectious disease: viral
05165 Human papillomavirus infection
102484859 (APC)
09164 Neurodegenerative disease
05010 Alzheimer disease
102484859 (APC)
05022 Pathways of neurodegeneration - multiple diseases
102484859 (APC)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102484859 (APC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
tup01009
]
102484859 (APC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tup03036
]
102484859 (APC)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
tup04812
]
102484859 (APC)
Protein phosphatases and associated proteins [BR:
tup01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
102484859 (APC)
Chromosome and associated proteins [BR:
tup03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
102484859 (APC)
Cytoskeleton proteins [BR:
tup04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
102484859 (APC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_rep
APC_u14
APC_u15
APC_u9
APC_N_CC
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
ARM_ARMC5
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
102484859
NCBI-ProteinID:
XP_006146951
LinkDB
All DBs
Position
Un
AA seq
2839 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPVGSFPR
RGLINGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAT
EAERSSQSKHDAGSREAEQQNEGQGVAETNMATSGGGQGSAPRVDPETASVLSSGSAHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNPRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
VDCEMHGLTSDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
ENKADICAVAGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDLGAVSMLKNLIHSKHKMIAM
GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
PKASHRSKQRHKPNLYGDYVFDSSRHDDNRSDSFNTGNMTVLSPYLNTTVLPSSSSSRGS
LESSRSEKDRSLERERGIGLSNYHPATENPGTSSKRGLQMSTTVAQIAKVMEEVSAIHTS
PEERSCGSTTELHGVADERNALRRSSAAHTHPNTYNFTKAENANRSCSMPYAKLEYKRSS
NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEEEIKQSEQRQSRSQSTTYPVYSE
STDDKHLKFQPHFGQQQRISPYRSRGASGSETNRVGSNHGLNQNVNQSLCQEDDYEDDKP
TNYSERYSEEEQHEEEERPTNYSMKYNEEKHHVDQPIDYSLKYATDIPPSQKPSFAFSKS
SSGQSTKTEHISSSGENTSTPPSNARRQSQPHPSSAQSRSGQTQKATSCKAPSVSQETVQ
TYCVEDTPICFSRCSSLSSLSSAEDEIGCDQTTQEAESANTLQITEMKENGGTRSADTPV
HEVPAVSQHVRTKSSRLPAPGLSSEPSRHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
PPPQTVQTKREVPKHKVPSAEKRESGPKPAAVNAAVQRVQVLPDVDTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESSENQEKEVEKPVDSE
KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPP
QNRLQAQKHVSFTPGDDMPRVYCVEGTPITFSTATSLSDLTIESPPNELAAGEGVRAGAQ
SGEKRDTIPTEGRSTDEAQRGKASAVTIPELEDSKTEEGDILAECINSAMPKGKSHKPFR
VKKIMDQVQQASAASSGTSKSQPDGKKKKPTSPVKPVPQNPEYRARGRRSTDSKNSLSAE
RAFSDSRDPKKQNSKNNPKDFSDKLPNNDDRVRGSFTFDSPHHYTPIEGTPYCFSRNDSL
SSLDFDDDDVDLSREKAELRKGKENKESEVKVTSHTEVASNQQSSNKTQAITKHSVSRCQ
PKPGLQKQSAFPQPSKDLPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNNN
KENEPVKETAPPASQGEPGKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE
CISSAMPKKKKPSRLKGDTEKHNPRNTSGILAEDLTLDLKDIQRPDSEHGLSPDSENFDW
KAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTS
NKGPRILKPGEKSTLETKKIESENKGIKGGKKVYKSLITGKVRSNSEVSSQLKQPLPTNM
PSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKPPASKSPSEGQAATTSPRGAKPSVRSE
LSPVSRQTAQIVGSNKGPSRSGSRDSTPSRPAQQPLSRPLQSPGRNSISPGRNGISPTNK
LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTAVSKNASSIPRSESASKGL
NQMSNGNGSNKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESAS
FESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYNDGR
PAKRHDIARSHSESPSRLPVNRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS
EKAKSEDEKHVNSTSGTKQTKESQVSTRGTWRKIKESEISPTNSTAQTTSSGASNGAESK
TLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGNPSVRENQGKQ
SVGNGSAPVRTAGLENRLNSFIQVDAPDQKGTETKPGQSNPVPASDTNESSVADRTPFSS
SSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSNSTKKRDSKTDSTE
SSGTQSPKRHSGSYLVTSV
NT seq
8520 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagcgtcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaaccttcgacaagaactagaagataattccaatcatcttacaaaactggaaactgag
gcctctaacatgaaggaagtacttaaacaacttcaaggaagtattgaagatgaagccatg
gcttcttctggacagattgatttgttagagcgtcttaaagagcttaacttagatagcagt
aatttccctggagtaaaactacggtcaaaaatgtccctccgttcttatggaagccgggaa
ggatctgtatccagtcgttcaggagagtgtagtcctgttcctgtgggttcgtttccaaga
agagggcttataaacgggagcagagaaaatacggggtatttagaagaactggagaaagaa
agatccttacttcttgctgatcttgacaaagaagaaaaggaaaaagactggtattatgct
caacttcagaatctcactaaaaggatcgacagtcttcctttaactgagaatttttcctta
cagacagacatgaccagaaggcaactggaatatgaagcacggcaaatcagagttgcgatg
gaagagcagctaggcacctgccaggatatggagaagcgggcacagcggcgaatagccaga
attcagcaaatagagaaggatatacttcgtgtacgacagcttttacaatcccaagcaaca
gaagcagagaggtcatcccagagcaagcatgacgccggctcacgagaagccgaacagcag
aatgaaggtcaaggagtggcagagaccaacatggcaacttctggtggtggtcagggctca
gctccacgagtggaccctgagacggccagtgtcctgagctctggtagcgctcactccgct
ccgcgaagactgaccagtcacctgggcactaaggtggaaatggtgtactcgctgctgtcc
atgcttggcactcacgataaggacgacatgtcgcggaccttgctggctatgtccagctcc
caggacagctgcatatccatgcgacagtcggggtgtcttcctctcctcatccagctatta
catggcaatgacaaagactctgtgttgttgggaaacccccggggcagtaaagaggctcgg
gccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgcgcgtactgtgaaacctgt
tgggagtggcaggaagcccatgagcaaggcatggaccaggacaaaaatccaatgcccgcc
ccggtcgagcaccagatctgccctgcggtgtgtgtcttaatgaaactttcatttgatgaa
gaacatagacatgcaatgaatgagctcgggggactgcaggccatcgcagagttactgcag
gtggactgtgagatgcacggactcaccagtgaccactacagcatcacgctgaggcgctac
gccgggatggccctgacaaacctgaccttcggcgacgtcgccaacaaggcgacgctgtgc
tccatgaaaggctgcatgagagcgctagtggcccagctgaaatccgagagcgaagactta
cagcaggttattgcaagtgttctgaggaacctgtcctggcgagccgatgtaaatagtaag
aagactctgcgggaagttggaagtgtaaaagcattgatggaatgtgctttggaagttaaa
aaggaatcgaccctcaaaagcgtcctgagtgccttgtggaacctgtcagcgcactgcact
gagaacaaggccgacatctgcgccgtggcgggcgcgctggccttcctggtcggcacgctc
acctaccggagccagaccaacaccctagccattattgagagcggaggtgggatactccgg
aacgtgtccagcctcattgctaccaacgaggaccacagacagatcctaagagagaacaac
tgcctacagaccttgttacaacacctgaagtctcacagtttgacgatagtcagcaatgcc
tgtggcacgctgtggaacctttcagcaaggaatcctaaagaccaagaagcattatgggac
ctgggggcagtcagcatgctcaagaacctcattcattcaaagcacaaaatgatcgctatg
ggaagtgctgcggctctaaggaatctcatggcaaataggcctgccaagtacaaggatgcc
aacattatgtctcctggctcaagcttgccttctcttcacgttaggaaacaaaaagccctg
gaagcagaactagatgctcagcacttatcagaaacttttgacaacattgacaacctaagt
cccaaggcgtctcaccgtagtaagcagagacacaagccaaacctctatggagactatgtt
ttcgactccagtcgccatgatgataaccgatcagacagttttaatactggaaacatgact
gtcctttcaccatatttgaatacgacggtgttgcccagctcttcatcatcaaggggaagt
ttagaaagttctcgttctgaaaaagatagaagtttagagagagagcgaggaattggccta
agcaactaccatccagcaacagaaaatccgggaacctcttcaaagcgaggtttgcagatg
tccaccactgtggcccagatcgctaaagtcatggaagaagtatccgccattcatacttcc
ccagaggagagaagttgcgggtccaccaccgaattgcatggtgtggcagatgagagaaac
gcactgagaaggagctctgctgcccacacacatccaaacacttacaatttcactaaggca
gaaaatgcaaatcggtcatgttctatgccttatgccaaactggaatataagagatcttca
aatgatagtttaaatagtgtcagcagtagtgatggttatggtaaaagaggtcagatgaag
ccctccattgaatcctattctgaagacgatgaaagtaaattttgcagttatggtcaatat
ccagctgacctagctcataaaattcatagtgcaaaccatatggatgacaatgatggagaa
ctggatacaccgataaattatagtcttaaatattcagatgagcagttgaactctggaagg
caaagtccttcacagaatgaaagatgggcaagacccaaacacataatagaagaggaaata
aaacaaagtgagcagagacaatcaaggagtcaaagcacaacttaccctgtatattctgag
agcactgacgataaacatctcaagttccagccacattttgggcaacagcaacgcatttcc
ccatataggtcaaggggagccagtggctcagaaacaaatcgagtgggttctaatcacgga
cttaatcaaaatgtaaaccagtctttgtgtcaggaagatgactatgaagatgacaagcca
accaactacagtgaacgttactctgaggaagaacagcatgaagaagaagaaagaccaaca
aattatagcatgaaatataatgaagaaaaacaccatgtggaccagcctattgattatagt
ttaaaatatgccacagacattcctccctcacagaaaccatcatttgcattctctaagagc
tcatctggacaaagcactaaaaccgaacacatctcttcaagtggtgagaatacgtccaca
cctccatctaatgccaggaggcagagccagccccatccaagctccgcacagagcagaagt
ggccagactcagaaagctacctcttgcaaagccccctctgtcagccaggagacagtacag
acgtactgtgtagaagatacccccatatgtttttccaggtgtagctcattatcgtctttg
tcatctgctgaggatgaaataggatgtgatcagacaacacaagaagcagagtctgctaac
actcttcagatcacagaaatgaaggaaaacggtggaactaggtccgccgacacgcctgtg
catgaagtcccagcggtctcccagcatgtcagaaccaaatccagcaggctcccagctcct
ggcttgtcttcagaacccagcaggcacaaagctgttgaattttcttcaggggctaaatct
ccttccaaaagtggtgctcagacacccaaaagtccacccgagcactacgtccaggagacg
ccactcatgttcagcagatgcacgtccgtcagttccctcgacagttttgagagccgttcc
attgccagctccgttcagagtgaaccgtgcagtggaatggtaagcggcattataagtccc
agtgaccttccagatagccctggacaaaccatgccacccagcagaagtaaaacccctcca
cctcctccgcagacagttcagaccaagcgagaggtgcccaaacacaaggtcccatctgct
gaaaagagagagagcgggccgaagccagccgctgtgaatgctgctgtccagagggtccag
gtccttccggatgtggacacgttgctgcactttgccacagaaagtaccccagacgggttc
tcttgttcgtctagcctgagcgccctgagccttgatgagccttttatacagaaagatgtg
gaattaagaatcatgcctcctgtccaggagaatgacaatgggaatgaaacagaatcagag
cagcctgaagaatctagtgaaaaccaggaaaaggaggtggaaaagcctgttgattctgaa
aaagatctgctagatgattcagatgatgatgacattgaaatactggaggaatgtattatt
tccgccatgcccacgaagtcatcacgcaaagccaaaaagccagcccagactgcttccaaa
ttacctccacctgtggcaaggaagcccagtcagctgcccgtgtacaaacttctgccacca
caaaaccgcttacaggcacagaagcatgtgagttttacgccaggggatgacatgccacga
gtgtactgtgtagaggggacaccgatcactttttccacagccacgtcgctaagtgatcta
acaatagaatctcctccaaacgagctagctgctggagaaggggttcgagcaggggcacag
tcgggtgaaaagcgagacaccattcccacagaaggcagaagcacagacgaggcccaaaga
ggaaaagcctcagctgtaaccataccagaactggaggatagtaaaacagaggaaggtgat
attcttgcagagtgcattaattctgcaatgcccaaaggaaaaagtcacaagcctttccgt
gtgaaaaaaataatggaccaggtccagcaagcatcagcggcttcatccggaaccagcaaa
agccagccagatggtaagaaaaagaaacctacttcgccagtaaaacccgtgccccagaat
cctgagtatagggcacgggggaggagaagtacggactcgaaaaatagtttaagtgctgag
agagctttctcagacagcagagatccgaagaagcagaactcgaaaaataatcccaaggac
ttcagtgataagctgccaaataacgacgacagagtcagaggaagctttacttttgattca
cctcatcattacacgcctattgaagggacgccatactgcttttcacggaatgattctttg
agttctctagattttgacgatgatgatgttgatctttctagggagaaggctgaattaaga
aaggggaaagagaataaggaatcagaagttaaagttaccagccacacggaagtagcctcg
aaccagcagtcctctaataagacacaagctattaccaaacattcggtaagtcggtgtcag
cccaaacccggactgcagaagcagtccgcctttccccagccatccaaggatctgccagac
agaggggcagcaaccgatgagaagctgcagaacttcgctattgaaaatactccagtctgc
ttttctcgtaattcttctctgagttctctcagtgacattgaccaagaaaacaacaacaac
aaagaaaacgaacctgtcaaagagactgcaccccctgcctctcagggagaaccaggcaaa
cctcaggcctccgggtatgctcctaaatcttttcatgttgaagatactcctgtttgtttc
tcaagaaacagttccctcagctctctcagcatcgactctgaagatgacctgttgcaggaa
tgtataagttctgccatgccgaaaaagaaaaagccttccagactcaagggtgatactgaa
aagcataatcccagaaatacgagtggcatattagcagaagatttgacacttgatttgaaa
gatatacagagaccagattcagaacatggtttatcccctgattccgaaaacttcgactgg
aaagctatccaggagggagcaaattccatagtgagtagtttacatcaggctgccgcggca
gcgtgtttgtctagacaggcttcctccgattccgattccatcctgtccctgaaatcgggg
atctccctgggatcaccatttcatctcacacccgatcaagaggagaagcccttcacaagt
aataaaggtccacgcattctgaaacctggggagaaaagtacgttggaaactaaaaagata
gaatctgaaaataaaggaatcaaaggaggaaagaaagtttataaaagtttgattactgga
aaagttcgatccaattcagaagtctcaagccagctgaagcagccccttccaacaaatatg
ccttccatctctcgaggtaggacaatgattcacatcccaggagttcgcaatagctcctca
agtacaagtcccgtctctaagaaaggcccaccccttaagcctccagcctccaaaagccct
agtgaaggccaggcagccaccacttctcctagaggagccaagccgtcggtgaggtcagag
ctaagccctgtgtccaggcagacagcgcagatcgtcgggtcaaataaagggccttctaga
tcggggtctagagactccaccccttccaggcctgcccagcagccgttaagtagaccgctg
cagtctccgggacgcaactccatctcccctggcaggaatggaatcagccctactaacaaa
ctgtcccagctgcccaggacatcatcccctagtactgcttccaccaagtcctcgggctca
gggaaaatgtcatacacgtccccaggcaggcagatgagccagcagaacctcaccaagcag
acggctgtgtccaagaatgccagtagcatcccaagaagtgagtctgcctccaaaggactg
aatcagatgagtaatggcaatgggtccaataaaaaggtagaactttctagaatgtcttcg
actaaatcaagtggaagtgaatctgataggtccgagagacctgtattagtacgccagtca
actttcatcaaagaggcgccaagcccaaccctgaggagaaagttggaggaatcggcttca
tttgaatctctgtccccctcttctagaccagactcccccactcggtcccaggcacagact
cccgtgttaagcccttccctcccagatatgtctctctccacgcatccgtctgtccaggct
ggcgggtggcggaaactcccgcccaatctcagtcccaccatcgaatacaacgacggcaga
ccggcgaagcggcacgacattgcacgttcccactccgaaagtccttccaggctgccagtc
aacaggtccggcacctggaagcgtgagcacagcaaacactcgtcgtcccttcctcgagtg
agcacgtggaggagaaccggaagctcgtcctcaattctgtctgcttcgtcagaatccagt
gaaaaagcaaagagtgaggatgaaaagcatgtgaactccacctcaggaaccaaacagaca
aaagaaagccaagtatccacaagaggaacgtggagaaaaatcaaagaaagtgaaatttct
cccacaaacagtactgctcagaccacttcctcaggtgcttcaaatggtgctgaatcaaag
actctcatctatcagatggcacctgctgtctctaaaacagaggacgtgtgggtgaggatc
gaggactgtcccattaacaaccctcggtctggaagatctcccacaggtaatactcccccg
gtgatcgacagtgtttcggaaaagggaaacccaagcgtcagagagaatcagggcaaacag
agcgtgggaaatggcagcgctcctgtgcgcaccgcgggtttggagaaccgcctgaactcc
tttattcaggtagatgccccagaccaaaaaggaaccgagacaaaacccggacaaagtaat
cccgtccccgcgtcagacactaacgagagttccgtggccgaccgaaccccgttcagctct
agcagctccagcaaacacagctcacccagtgggactgtggctgccagagtgactcctttc
aattacaacccgagccctaggaagagcagcgccgacagcacttcagcccggccctcgcag
atcccgaccccggtcagcaacagcacaaagaagcgagattccaaaactgacagcacagag
tccagcgggacgcaaagtccgaagcgccattctgggtcttaccttgtgacatctgtttaa
DBGET
integrated database retrieval system
