Tupaia chinensis (Chinese tree shrew): 102485304 Help Entry 102485304         CDS       T02978                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup01522   Endocrine resistance tup03272   Virion - Hepatitis viruses tup04010   MAPK signaling pathway tup04012   ErbB signaling pathway tup04014   Ras signaling pathway tup04015   Rap1 signaling pathway tup04020   Calcium signaling pathway tup04066   HIF-1 signaling pathway tup04068   FoxO signaling pathway tup04072   Phospholipase D signaling pathway tup04144   Endocytosis tup04151   PI3K-Akt signaling pathway tup04510   Focal adhesion tup04520   Adherens junction tup04540   Gap junction tup04630   JAK-STAT signaling pathway tup04810   Regulation of actin cytoskeleton tup04912   GnRH signaling pathway tup04915   Estrogen signaling pathway tup04921   Oxytocin signaling pathway tup04926   Relaxin signaling pathway tup04928   Parathyroid hormone synthesis, secretion and action tup04934   Cushing syndrome tup05160   Hepatitis C tup05163   Human cytomegalovirus infection tup05165   Human papillomavirus infection tup05171   Coronavirus disease - COVID-19 tup05200   Pathways in cancer tup05205   Proteoglycans in cancer tup05206   MicroRNAs in cancer tup05207   Chemical carcinogenesis - receptor activation tup05208   Chemical carcinogenesis - reactive oxygen species tup05210   Colorectal cancer tup05212   Pancreatic cancer tup05213   Endometrial cancer tup05214   Glioma tup05215   Prostate cancer tup05218   Melanoma tup05219   Bladder cancer tup05223   Non-small cell lung cancer tup05224   Breast cancer tup05225   Hepatocellular carcinoma tup05226   Gastric cancer tup05230   Central carbon metabolism in cancer tup05231   Choline metabolism in cancer tup05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:tup00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03272 Virion - Hepatitis viruses     102485304 (EGFR)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     102485304 (EGFR)    04015 Rap1 signaling pathway     102485304 (EGFR)    04630 JAK-STAT signaling pathway     102485304 (EGFR)    04066 HIF-1 signaling pathway     102485304 (EGFR)    04068 FoxO signaling pathway     102485304 (EGFR)    04072 Phospholipase D signaling pathway     102485304 (EGFR)    04151 PI3K-Akt signaling pathway     102485304 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     102485304 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04915 Estrogen signaling pathway     102485304 (EGFR)    04921 Oxytocin signaling pathway     102485304 (EGFR)    04926 Relaxin signaling pathway     102485304 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     102485304 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102485304 (EGFR)    05206 MicroRNAs in cancer     102485304 (EGFR)    05205 Proteoglycans in cancer     102485304 (EGFR)    05207 Chemical carcinogenesis - receptor activation     102485304 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     102485304 (EGFR)    05230 Central carbon metabolism in cancer     102485304 (EGFR)    05231 Choline metabolism in cancer     102485304 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102485304 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     102485304 (EGFR)    05212 Pancreatic cancer     102485304 (EGFR)    05225 Hepatocellular carcinoma     102485304 (EGFR)    05226 Gastric cancer     102485304 (EGFR)    05214 Glioma     102485304 (EGFR)    05218 Melanoma     102485304 (EGFR)    05219 Bladder cancer     102485304 (EGFR)    05215 Prostate cancer     102485304 (EGFR)    05213 Endometrial cancer     102485304 (EGFR)    05224 Breast cancer     102485304 (EGFR)    05223 Non-small cell lung cancer     102485304 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     102485304 (EGFR)    05171 Coronavirus disease - COVID-19     102485304 (EGFR)    05163 Human cytomegalovirus infection     102485304 (EGFR)    05165 Human papillomavirus infection     102485304 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102485304 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102485304 (EGFR)    01522 Endocrine resistance     102485304 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102485304 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:tup04147]     102485304 (EGFR) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102485304 (EGFR) Protein kinases [BR:tup01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    102485304 (EGFR) Exosome [BR:tup04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    102485304 (EGFR)   Exosomal proteins of pancreatic cancer cells    102485304 (EGFR)   Exosomal proteins of bladder cancer cells    102485304 (EGFR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like GAPT ABC1 Motif Other DBs NCBI-GeneID:  102485304 NCBI-ProteinID:  XP_006148980 LinkDB All DBs Position Un AA seq 1246 aa AA seqDB search MVIQQQKIKAPEAPRRLQYANQATVCSDHYWPQAGPSQEQRWPLLWEQGQPGRHSCDVAA AGDHGEVCQGTSNRLTQLGTFEDHFLSLQRILNNCEVVLGNLEITYVQRNYDLSFLKTIQ EVAGYVLIALNTVERIPLENLQIIRGNVLYENSYALAVLSNYGANKTGLRELPMRNLQEI LHGAVRFSNNPFLCNVESIQWRDIVNVNFLSNMSLDFRSHSSSCQKCNPGCPNGSCWGAG EENCQKLTKVICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDT CPPLMLYNPTTYQMDVNSEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDSYEMEEDGV RKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFKNCTSISGDLHILPVAFKGDSFTR TPPLDPKELDILKTVKEITGFLLIQAWPGNRTDLHAFENLEIIRGRTKQHGQFSLAVVGL NITSLGLRSLKEISDGDVIISGNPNLCYADTISWKTLFGTSSQKTKIMNNREENSCKTTD HICNALCSSEGCWGPEARDCVSCRNVSRGKECVERCNVLEGEPREFVENSECIQCHPECL PQDMNITCTGRGPDNCIKCAHFIDGPHCVKTCPAGIMGENNTLVWKYADANRVCHLCHSN CTYGCAGPGLEGCSINGPKIPSIATGIVGGLLLLLLVALGIGLFLRRRHIVRKRTLRRLL QERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVA IKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVR EHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLG AEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEI SSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQG DERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSVTSN NSTVACIDRNGQSYPVKEDSFIQRYSSDPTGALTEDNIDDIFLPVPEYINQSVPKRPAGS VQNPVYHNQPLNPAPGRDPHYQNPHSNAVDNPEYLNTAQPTCVNSVFDSPAHWAQKSNHQ ISLDNPDYQQDFFPKEAKPNGIFKGPAAENAEYLRVAPPSSEFIGA NT seq 3741 nt NT seq  +upstreamnt  +downstreamnt atggtcattcagcagcagaaaatcaaggcaccagaagcccctagacggctgcagtatgca aatcaggccacggtctgcagtgaccactactggccccaggcagggccctcccaggagcag aggtggcccctgctgtgggagcagggccagccagggcggcacagctgtgatgtggcagca gctggcgaccacggggaagtttgccagggcaccagtaacaggctcacacagttgggcacc tttgaagatcacttcctgagcctccagaggatactgaataactgtgaagtggtccttgga aatttggaaatcacctacgtgcaaaggaattacgacctttccttcttaaagaccattcag gaggttgctggttatgtcctcattgccctgaacacagtggagaggatccccttggaaaac ttgcagatcatcagaggaaatgtgctctatgaaaactcctatgccctggcagtcttgtcc aactatggtgcaaataaaactggactaagggagctgcccatgaggaacttacaggaaatc ctgcatggtgctgtgcgattcagcaacaaccccttcctctgcaacgtggagtccatccag tggcgggacatcgtcaacgtcaacttcctgagcaatatgtcactggacttccggagccat tcaagcagttgccagaagtgcaatccgggctgtcctaatggaagctgctggggtgcaggc gaagaaaactgccagaagctgaccaaagtcatctgtgcccagcagtgttcggggcgctgc cgcggcaagtcccccagtgactgctgtcacaaccagtgtgctgccggctgcaccgggccc cgtgagagcgactgcctggtctgccgcaagttccgagatgaagccacgtgcaaggacacg tgtcccccgctcatgctatacaaccctaccacgtaccagatggacgtcaactccgagggg aagtacagctttggtgccacctgtgtgaagaaatgcccccgtaactacgtggtgacagat cacggctcgtgcgtccgcgcctgcggacctgacagctacgagatggaggaagatggcgtc cgcaagtgcaaaaagtgcgaagggccttgtcgcaaagtgtgtaacggaataggaattggt gaattcaaagatacgctttccataaatgctacaaatatcaaacacttcaaaaactgcacc tccatcagcggagatctgcacatcctgccggtcgcatttaagggcgactccttcacacgc actcctcctctggatccgaaggaactggacattctaaaaaccgtaaaggaaataacaggg ttcttgctgatccaggcatggcctggaaacaggactgacctacatgctttcgagaaccta gaaatcattcgcggcaggacaaagcaacatggtcagttttctctcgcagttgttggcctg aacataacgtccttgggattacggtccctcaaggagatcagtgatggagatgtgatcatt tcgggaaacccaaatttgtgctatgcagacacaatcagctggaaaacactgtttgggacc tccagtcagaaaaccaaaattatgaacaacagagaggaaaacagctgcaagaccacagac cacatctgtaacgcgttatgctcctcagagggctgctggggtccggaggccagggactgt gtctcctgccgaaacgtcagccgtggcaaggagtgtgtggagaggtgcaacgtgctggag ggagagccgcgggagttcgtggagaattccgagtgtatccagtgccatccggaatgtctg ccccaggacatgaacataacctgcacgggacggggaccagacaactgcatcaagtgtgcc cacttcattgatggccctcactgtgtcaagacctgcccagctggaatcatgggagaaaat aacaccctggtctggaagtacgccgatgccaaccgcgtatgtcacctgtgccattccaac tgcacctatggatgtgctgggccaggtcttgaaggctgttcaatcaatgggcccaagatc ccttccatcgccaccgggattgtgggcggcctcctcttgctgctgctggtggccctcggg atcggccttttcctgcgcaggcgccacatcgtccggaagcgcaccctgcgccgactgctg caggaaagagagctcgttgagcctctcacgcccagtggagaagctcccaaccaggctctc ttgaggatcttaaaggaaacggaattcaaaaagatcaaagtgctgggttctggagcgttc ggtactgtgtacaagggactctggatcccagaaggtgagaaagttaaaattcctgtggcc atcaaggaattgagagaagcgacgtctccaaaagccaacaaggaaatcctcgatgaggcc tatgtgatggccagcgtggacaatccccatgtgtgccggctcctgggcatctgcctgacc tccacagtccagctcatcacacagctcatgcccttcggctgcctcctggactacgtccgt gagcacaaggacaacataggctcccagtacctcctcaactggtgtgtgcagattgccaag ggaatgaactacctggaagaccggcgcttggtgcaccgtgacctggcagccaggaatgtc ctggtgaagaccccacagcatgtgaagatcacagattttgggttggccaaactgcttggt gctgaagagaaggaatatcatgcagaaggaggcaaagtgcccatcaagtggatggccttg gaatcgattttacaccgcatctatacccaccaaagtgatgtctggagctatggagtcact gtttgggagttgatgacctttgggtccaagccttatgacgggatccctgcaagtgagatc tcgtcgatcctggagaaaggggagcgtctgccgcagccacccatatgcaccatcgacgtc tacatgatcatggtcaagtgctggatgatagatgcagacagtcgccctaagttccgagaa ttgatcatcgaattctccaaaatggcccgagacccccaacgttaccttgtcattcagggg gatgaaagaatgcacctgccgagccctacagactccaacttctaccgggccctgatggac gaagaggacatggaagacgtcgtagacgctgacgagtacctcatcccacagcagggcttc ttcaacagcccttccacctcccgcactcccctcttgagttctctgagtgtgaccagcaac aactccaccgtggcttgcatcgacagaaatgggcagagctaccctgtcaaagaagacagc ttcatccagcgctacagctcagaccccactggtgccttgactgaggacaacatagatgac atcttccttccagtgccagaatacataaaccagtcggttcccaaaaggcctgcaggctct gtgcagaatcctgtctatcacaatcagcctctgaatcctgctcctgggagagacccacac taccaaaacccccacagcaatgcagtggacaaccctgagtatctcaacaccgcccagcct acctgtgtcaacagtgtatttgacagccctgcccactgggcccagaaaagcaaccaccag attagcctggacaaccctgactaccaacaggacttctttcccaaggaagctaagccaaat ggtatctttaagggtcctgcagctgaaaatgcagaatacctaagggtagcaccaccgagc agtgaattcattggagcgtga

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