Tupaia chinensis (Chinese tree shrew): 102485847
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Entry
102485847 CDS
T02978
Symbol
MET
Name
(RefSeq) MET proto-oncogene, receptor tyrosine kinase
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521
EGFR tyrosine kinase inhibitor resistance
tup04010
MAPK signaling pathway
tup04014
Ras signaling pathway
tup04015
Rap1 signaling pathway
tup04020
Calcium signaling pathway
tup04151
PI3K-Akt signaling pathway
tup04360
Axon guidance
tup04510
Focal adhesion
tup04520
Adherens junction
tup05100
Bacterial invasion of epithelial cells
tup05144
Malaria
tup05200
Pathways in cancer
tup05202
Transcriptional misregulation in cancer
tup05205
Proteoglycans in cancer
tup05206
MicroRNAs in cancer
tup05208
Chemical carcinogenesis - reactive oxygen species
tup05211
Renal cell carcinoma
tup05218
Melanoma
tup05223
Non-small cell lung cancer
tup05225
Hepatocellular carcinoma
tup05226
Gastric cancer
tup05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102485847 (MET)
04014 Ras signaling pathway
102485847 (MET)
04015 Rap1 signaling pathway
102485847 (MET)
04020 Calcium signaling pathway
102485847 (MET)
04151 PI3K-Akt signaling pathway
102485847 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102485847 (MET)
04520 Adherens junction
102485847 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
102485847 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102485847 (MET)
05202 Transcriptional misregulation in cancer
102485847 (MET)
05206 MicroRNAs in cancer
102485847 (MET)
05205 Proteoglycans in cancer
102485847 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
102485847 (MET)
05230 Central carbon metabolism in cancer
102485847 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102485847 (MET)
05226 Gastric cancer
102485847 (MET)
05218 Melanoma
102485847 (MET)
05211 Renal cell carcinoma
102485847 (MET)
05223 Non-small cell lung cancer
102485847 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
102485847 (MET)
09174 Infectious disease: parasitic
05144 Malaria
102485847 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102485847 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102485847 (MET)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102485847 (MET)
Protein kinases [BR:
tup01001
]
Receptor tyrosine kinases (RTK)
MET family
102485847 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
PepSY_TM
Motif
Other DBs
NCBI-GeneID:
102485847
NCBI-ProteinID:
XP_006162438
LinkDB
All DBs
Position
Un
AA seq
1400 aa
AA seq
DB search
MKSNSEGLTECLARDKFLTMKAPTVLAPGILVLLFTLVQRSNGECTEALIKSKMNVDMEY
QLPNFTAATPIQNIVLHKNHIYLGAINYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQNC
RSKANSSGGTWKDNINMALLVDTYYDDQLISCGSVNRGTCLRHVFPRGNPADIQSEVHCM
FSPQADEEPSQCPDCVVSPLGTKVLLSEKNRFITFFVGNTINNSYLPDHSLHSISVRRLK
ETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQKETLDAQTFHTRIIR
FCSVDSGLHSYMEMPLECILTEKRRKRSTRKEVFNILQAAYVSKPGAHLAKQIGASQNDD
ILYGVFAQSKADSAEPVNRSAVCAFPVKYINEFFNKIVNKNNVRCLQHFYGPNHEHCFNR
TLLRNSTGCEVRSDEYRTEFTTALPRVDLFMGQFKEVLLTSISTFIKGDLTIANLGTAEG
RFMQVELSRSGSTPHVNFHLDSHPVSPDMIVKQRLNQSGYTLVVTGKKLTKIPLNGLGCG
HFQSCSQCLSAPPFVQCGWCHDKCVQLEDCPSGTWTQELCLPAIHKVFPTSAPLEGGTTL
TICGWDFGFRKNNKFDLKKTRVFLGNESCTLTLSESTKNMLKCTVGPLMTEHFNMSIIIS
NGRGTTQYNTFSYVDPIITSLSPSYGPKAGGTLLTLTGKYLSSGTSRHISIGGKTCTLKS
VSNSILECYTPAQTISTEFPVKLKIDLANRETSSFSYLENPIVHEIYPTKSFLSGGSTIT
GVGKNLNSVSVPKMVINVLEAEKNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
LLDGTPSRYFDLTYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
CENIHSHSEAVLCTVPNDLLKLNSELNIEWKQAVSSTLLGKVIVQPDQNFTGLIVGVAAI
STILLLLLGLFLWLKKRKRIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
DYRATFPEDQFPIASQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSTLNPE
LVQAVQHVVIGPNRLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEV
SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
IGFGLQVAQGMKYLASKNFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
LLQPEYCPDPLFEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
LAPYPSLLSSQDDIDGEVDT
NT seq
4203 nt
NT seq
+upstream
nt +downstream
nt
atgaagagtaattcagagggtttaacagaatgcctggcacgtgataaatttctcaccatg
aaggcccccactgtgcttgcacctggcatccttgtgctcctgtttaccttggtgcagagg
agcaatggggagtgtacagaggcactgataaagtccaagatgaatgtcgatatggagtat
cagcttcccaacttcactgcagcaacacccatacagaatattgttctacataagaatcac
atttacctcggcgccattaactacatttatgttttaaatgataaagaccttcagaaggtt
gctgagtacaagactgggcccgtgctagaacacccagattgttttccatgtcagaactgc
aggagcaaggccaattcatcaggtggcacttggaaagataacatcaacatggctctgctt
gttgacacgtactatgatgaccaactcattagctgtggcagtgtcaacagagggacctgc
ctacgacacgtctttccccgtggtaatcctgctgatatacagtcagaggtgcattgcatg
ttctccccacaggcagacgaggagcccagccagtgtcctgactgtgtggtgagccccctg
ggaaccaaagtcctcctgtctgaaaagaaccggttcatcaccttctttgtaggcaatacc
ataaataattcttaccttccagatcattcactgcattcgatatcggtgagaagactaaag
gaaacacaagatggttttaagtttttgacagaccagtcatatattgatgttttacctgag
ttccgggattcttaccccattaagtatgtccatgccttcgaaagcaaccattttatttac
tttttgacagtccaaaaagaaactctagatgctcaaacttttcacacgcgaatcatcaga
ttctgttctgtggactctgggttgcattcttacatggaaatgcctctggaatgtattctc
acggaaaagagaagaaagagatccacaagaaaggaagtattcaatatccttcaggctgca
tatgtcagtaaacctggggcccatcttgctaagcaaataggagccagccagaatgatgac
attctctacggggtgttcgcacaaagcaaggcagattctgccgaaccagtgaatcgatct
gctgtctgcgcattccctgtcaaatatatcaatgaattcttcaataagatcgtcaacaaa
aacaatgtgagatgtctccagcacttttatggacccaatcatgagcactgttttaatagg
acacttctgagaaattcaacaggctgtgaagtacgcagtgatgaataccgaacagagttt
accacagctttgccgcgcgttgacttattcatgggccaattcaaagaagtcctcttaaca
tctatatccaccttcattaagggagacctcactattgctaatcttgggaccgcagagggt
cgcttcatgcaggttgaactttctagatctggatcaactcctcatgtgaattttcacctg
gattcccaccctgtgtctccagatatgattgtgaaacaacgattaaaccaaagtggctac
acactggttgtcactgggaagaagctcaccaagatcccattaaatggcttgggctgtgga
catttccaatcctgcagtcagtgtctctctgcccctccctttgtgcagtgtggctggtgt
catgataaatgtgtgcaattggaggattgtcccagcgggacctggactcaagagctctgt
ctacctgcaatccataaggttttcccaactagtgcaccccttgaaggagggacaacgttg
accatatgtggctgggactttggattcagaaagaataataaattcgatttaaagaaaact
agagttttcctcggaaatgagagctgcaccttgaccttaagtgagagcacaaaaaatatg
ttgaaatgtacagttggtcctctaatgactgagcattttaatatgtccataattatttca
aatggccgagggacaacacaatataatacattttcttatgtggatcctatcattacaagt
ctttctccaagctatggtccaaaggctggcggcactttacttactttaactggaaagtac
ctaagcagtgggacttctagacacatttcaattggtggaaaaacatgtactttaaaaagt
gtgtcaaatagtattcttgaatgttataccccagcgcaaactatttcaactgagtttcct
gttaaattgaaaattgacttagccaaccgagagaccagcagcttcagttacctggaaaac
cctattgtccatgaaatttatccaaccaagtcttttcttagtggtgggagcacaataaca
ggtgttggaaaaaatttgaattcagttagtgtcccaaagatggtaataaatgtgcttgaa
gcagaaaagaacttcacagtggcctgtcaccatcgctctaattcagagataatatgctgt
acaactccttcattacaacagctgaatctgcagctccctctgaaaaccaaagcctttttc
ctgttagatgggaccccttccagatactttgatctcacttatgtacataatcctgtgttt
aagccttttgaaaagccagtgatgatctcaatgggcaatgaaaatgtactggaaattaag
ggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataagagc
tgtgagaacatacactcacattctgaagccgttttatgtacagtccccaatgacctgctg
aaattgaacagcgagctaaatatagagtggaagcaagcagtttcttcaaccttacttggg
aaagtaatagttcaacctgaccagaattttacaggactgattgtgggtgttgccgcaata
tcaacaatactcttattactactcgggcttttcctgtggctgaaaaagagaaagcgaatt
aaagacctgggcagtgaattagttcgctatgatgcaagagttcacacccctcatttggac
aggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaatctgta
gactaccgagctacttttccagaagaccagtttcccattgcatctcagaatggatcatgc
cgacaagtgcagtatcctctgacggacctgtcccccatcctaacaagtggggactctgat
atatccagtccattactgcaaaatactgtccacattgacctcagcactctaaatccagag
ctggtccaggcagtgcagcatgtggtgattgggccgaacaggctgatcgtgcatttcaat
gaagtcataggaagaggacattttggttgtgtatatcatgggaccttgttggacaatgac
gacaaaaaaattcactgtgctgtgaaatccttgaacagaattactgacataggagaagtt
tcccagtttctaaccgagggaatcatcatgaaagactttagccatcccaatgtcctctcc
ctgctgggaatctgccttcgaagtgaagggtctcccctggtggtcttaccatacatgaaa
catggagatcttcgaaatttcattcgaaatgagactcataacccaactgtaaaagattta
attggctttggtcttcaagtagcccaaggcatgaaataccttgcaagcaaaaattttgtc
cacagagacttggctgcaagaaactgtatgctggatgaaaaatttaccgtcaaggttgct
gattttggtctcgccagagatatgtatgataaagaatactatagtgtacacaacaaaaca
ggtgcaaaactgccagtgaagtggatggctttggaaagtctgcaaactcagaagttcacc
accaagtcagatgtgtggtcctttggtgtgctcctctgggagctaatgacaagaggagcc
cctccgtaccctgatgtgaacacctttgatataaccgtttacttgttgcaaggcagaagg
ctcttgcagcccgaatactgcccggaccccttgtttgaagtgatgctaaaatgctggcat
cctaaagccgaaatgcgcccatccttttctgaactggtctcgaggatatcggccatcttc
tctactttcatcggggagcactatgtccatgtgaacgccacttatgtgaatgtgaaatgt
ctagctccatatccttctctgttgtcatcacaggatgacattgatggagaggtggacacc
tga
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