KEGG   Tupaia chinensis (Chinese tree shrew): 102486692
Entry
102486692         CDS       T02978                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04120  Ubiquitin mediated proteolysis
tup04380  Osteoclast differentiation
tup04630  JAK-STAT signaling pathway
tup04668  TNF signaling pathway
tup04910  Insulin signaling pathway
tup04917  Prolactin signaling pathway
tup04920  Adipocytokine signaling pathway
tup04930  Type II diabetes mellitus
tup04931  Insulin resistance
tup04932  Non-alcoholic fatty liver disease
tup04935  Growth hormone synthesis, secretion and action
tup05160  Hepatitis C
tup05164  Influenza A
tup05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:tup00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102486692 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102486692 (SOCS3)
   04668 TNF signaling pathway
    102486692 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102486692 (SOCS3)
   04920 Adipocytokine signaling pathway
    102486692 (SOCS3)
   04917 Prolactin signaling pathway
    102486692 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    102486692 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102486692 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102486692 (SOCS3)
   05164 Influenza A
    102486692 (SOCS3)
   05168 Herpes simplex virus 1 infection
    102486692 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102486692 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    102486692 (SOCS3)
   04931 Insulin resistance
    102486692 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:tup04121]
    102486692 (SOCS3)
Ubiquitin system [BR:tup04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     102486692 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 102486692
NCBI-ProteinID: XP_006145770
LinkDB
Position
Un
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPRQGSSFPSPPTEPSSQPASEPEPAQPLPGTAPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLGSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtacgcaag
ctgcaggagagcggcttctactggagcgctgtgactggcggtgaggcgaacctgctgctc
agcgccgagcccgcgggcaccttcctcatccgtgacagctcggaccagcgccacttcttc
acgctcagcgtcaagactcagtccgggaccaagaacctgcgcatccagtgcgaggggggc
agcttctcgctgcagagcgacccccgcagcacgcagccggtgccccgtttcgactgcgtg
ctcaagctggtgcatcattacatgccacggcagggctcttccttcccctcgccgcccacc
gagccctcctcccagccggcctcggagccggagcccgcccagcctctcccaggaaccgcc
cccaggagagcctactacatctactctgggggcgagaagatccccctggtgttgagccgg
cccctctcctccaatgtggccacccttcagcatctctgtcggaagactgtcaacggccac
ctgggttcctatgagaaggtcacccagttgcctgggcccatccgggagttcctggaccag
tatgatgccccgctttaa

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